Simultaneous determination of fimasartan, a novel antihypertensive agent, and its active metabolite in rat plasma by liquid chromatography-tandem mass spectrometry

Beom Soo Shin; Tae Hwan Kim; Soo Heui Paik; Yong Ha Chi; Joo Han Lee; Hyun Kwang Tan; Yohan Choi; Minki Kim; Sun Dong Yoo

doi:10.1002/bmc.1592

Simultaneous determination of fimasartan, a novel antihypertensive agent, and its active metabolite in rat plasma by liquid chromatography-tandem mass spectrometry

Biomedical Chromatography ◽

10.1002/bmc.1592 ◽

2011 ◽

Vol 25 (11) ◽

pp. 1208-1214 ◽

Cited By ~ 14

Author(s):

Beom Soo Shin ◽

Tae Hwan Kim ◽

Soo Heui Paik ◽

Yong Ha Chi ◽

Joo Han Lee ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Active Metabolite ◽

Antihypertensive Agent ◽

Rat Plasma ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Enantioselective determination of 1-[4-(2-methoxyethyl)phenoxy]-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanol hydrochloride, a novel antihypertensive agent, in rat plasma and tissues by liquid chromatography-tandem mass spectrometry

Journal of Separation Science ◽

10.1002/jssc.201700710 ◽

2017 ◽

Vol 40 (21) ◽

pp. 4135-4141 ◽

Cited By ~ 3

Author(s):

Sijie He ◽

Sanlan Wu ◽

Wenwen Zhu ◽

Yeli Guan ◽

Gao Li ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Antihypertensive Agent ◽

Rat Plasma ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Simultaneous determination of asperosaponin VI and its active metabolite hederagenin in rat plasma by liquid chromatography–tandem mass spectrometry with positive/negative ion-switching electrospray ionization and its application in pharmacokinetic study

Journal of Chromatography B ◽

10.1016/j.jchromb.2011.09.014 ◽

2011 ◽

Vol 879 (30) ◽

pp. 3407-3414 ◽

Cited By ~ 21

Author(s):

He Zhu ◽

Li Ding ◽

Shailendra Shakya ◽

Xiemin Qi ◽

Linlin Hu ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Active Metabolite ◽

Rat Plasma ◽

Negative Ion ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Simultaneous determination of thienorphine and its active metabolite thienorphine-glucuronide in rat plasma by liquid chromatography–tandem mass spectrometry and its application to pharmacokinetic studies

Journal of Chromatography B ◽

10.1016/j.jchromb.2007.09.028 ◽

2007 ◽

Vol 859 (1) ◽

pp. 52-61 ◽

Cited By ~ 7

Author(s):

Qi Kong ◽

Jianzhong Qiao ◽

Xiaoying Wang ◽

Shulan Yuan ◽

Zhenqing Zhang ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Active Metabolite ◽

Rat Plasma ◽

Pharmacokinetic Studies ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Determination of cefuroxime in liver-injured rat plasma by ultra fast liquid chromatography-tandem mass spectrometry via acidified protein precipitation

Chinese Journal of Chromatography ◽

10.3724/sp.j.1123.2012.03001 ◽

2013 ◽

Vol 30 (7) ◽

pp. 705-710 ◽

Cited By ~ 3

Author(s):

Longshan ZHAO ◽

Qing LI ◽

Wei YANG ◽

Bosai HE ◽

Binbin WEI ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Rat Plasma ◽

Protein Precipitation ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Fast Liquid Chromatography

Download Full-text

Quantitative determination of proxalutamide in rat plasma and tissues using liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.9003 ◽

2020 ◽

Vol 35 (3) ◽

Author(s):

Hua Sang ◽

Yu Wang ◽

Yunxi Zhong ◽

Shiyin Gu ◽

Guangji Wang ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Quantitative Determination ◽

Rat Plasma ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Simultaneous determination of 3‐ n ‐butylphthalide and its metabolite 10‐hydroxy‐butylphthalide in rat plasma by using liquid chromatography tandem mass spectrometry and application to a pharmacokinetic study

Biomedical Chromatography ◽

10.1002/bmc.5184 ◽

2021 ◽

Author(s):

Li‐Shu Lin ◽

Li‐Ling Lin ◽

Tao Lin ◽

Yan‐An Wu

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Simultaneous Determination ◽

Pharmacokinetic Study ◽

Rat Plasma ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Determination of BAPTA-AM, the acetoxymethyl tetraester of BAPTA, in rat plasma by liquid chromatography tandem mass spectrometry

Journal of Mass Spectrometry ◽

10.1002/jms.1125 ◽

2006 ◽

Vol 41 (12) ◽

pp. 1615-1622 ◽

Cited By ~ 3

Author(s):

Feng Zheng ◽

Taijun Hang ◽

Chunyong Wu ◽

Bin Di ◽

Wenyin Liu ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Rat Plasma ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Simultaneous determination of amodiaquine and its active metabolite in human blood by ion-pair liquid chromatography–tandem mass spectrometry

Journal of Chromatography B ◽

10.1016/j.jchromb.2007.09.040 ◽

2007 ◽

Vol 860 (1) ◽

pp. 18-25 ◽

Cited By ~ 14

Author(s):

X CHEN ◽

P DENG ◽

X DAI ◽

D ZHONG

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Human Blood ◽

Active Metabolite ◽

Ion Pair ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text

Development and validation of a liquid chromatography–tandem mass spectrometry method for the determination of zofenopril and its active metabolite zofenoprilat in human plasma

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2011.02.010 ◽

2011 ◽

Vol 55 (3) ◽

pp. 527-532 ◽

Cited By ~ 3

Author(s):

Yuan Jiang ◽

Fang Yan ◽

Bin Di ◽

Fang Feng ◽

Linjun You ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Active Metabolite ◽

Tandem Mass ◽

Spectrometry Method ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Development And Validation

Download Full-text

Liquid chromatography/tandem mass spectrometry for the determination of carbamazepine and its main metabolite in rat plasma utilizing an automated blood sampling system

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2004.11.058 ◽

2005 ◽

Vol 38 (1) ◽

pp. 119-125 ◽

Cited By ~ 37

Author(s):

Yongxin Zhu ◽

Hwa Chiang ◽

M. Wulster-Radcliffe ◽

Rita Hilt ◽

Philip Wong ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Rat Plasma ◽

Tandem Mass ◽

Sampling System ◽

Main Metabolite ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass

Download Full-text