scholarly journals Structural genomics and high-throughput structural biology

2007 ◽  
Vol 35 (6) ◽  
pp. 483-484
Author(s):  
Gale Rhodes
Keyword(s):  
Structural Biology ◽  
High Throughput ◽  
Structural Genomics

scholarly journals NIGMS PSI:Biology Initiative ‐ Enabling High‐Throughput Structural Biology and Structural Genomics

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Peter C. Preusch ◽  
Ravi Basavappa ◽  
Jean Chin ◽  
Charles Edmonds ◽  
Paula Flicker ◽  
...  
Keyword(s):  
Structural Biology ◽  
High Throughput ◽  
Structural Genomics

Automated seeding for the optimization of crystal quality

2010 ◽  
Vol 43 (4) ◽  
pp. 752-756 ◽  
Author(s):  
Sahir Khurshid ◽  
Lesley F. Haire ◽  
Naomi E. Chayen
Keyword(s):  
High Throughput ◽  
Structural Genomics ◽  
Optimization Method ◽  
Crystal Quality ◽  
Routine Manner

With the advent of structural genomics a variety of crystallization techniques have been automated and applied to high-throughput pipelines, yet seeding, which is the most common and successful optimization method, is still being performed predominantly manually. The aim of this study was to devise simple automated seeding techniques that can be applied in a routine manner using existing robots and not requiring special tools. Two alternative protocols for automated seeding experiments are described. One involves the delivery of microcrystals from stock to target wells using the robot dispensing tip as a seeding tool. The second harnesses an animal whisker as the seeding tool. Larger and better ordered crystals were obtained using both techniques.

scholarly journals NIGMS PSI:Biology Initiative -- High-Throughput-Enabled Structural Biology

2010 ◽  
Vol 98 (3) ◽  
pp. 250a
Author(s):  
Peter C. Preusch ◽  
Ravi Basavappa ◽  
Jean Chin ◽  
Charles Edmonds ◽  
Ward Smith ◽  
...  
Keyword(s):  
Structural Biology ◽  
High Throughput

RIKEN structural genomics beamlines at the SPring-8; high throughput protein crystallography with automated beamline operation

2006 ◽  
Vol 7 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Go Ueno ◽  
Hiroyuki Kanda ◽  
Raita Hirose ◽  
Koh Ida ◽  
Takashi Kumasaka ◽  
...  
Keyword(s):  
High Throughput ◽  
Structural Genomics ◽  
Protein Crystallography

scholarly journals Automated cryo-lamella preparation for high-throughput in-situ structural biology

2020 ◽  
Vol 210 (2) ◽  
pp. 107488 ◽  
Author(s):  
Genevieve Buckley ◽  
Gediminas Gervinskas ◽  
Cyntia Taveneau ◽  
Hariprasad Venugopal ◽  
James C. Whisstock ◽  
...  
Keyword(s):  
Structural Biology ◽  
High Throughput
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