Liver damage during organ donor procurement in donation after circulatory death compared with donation after brain death

2012 ◽  
Vol 100 (3) ◽  
pp. 381-386 ◽  
Author(s):  
F. Ausania ◽  
S. A. White ◽  
R. Coates ◽  
W. Hulme ◽  
D. M. Manas
Keyword(s):  
Brain Death ◽  
Liver Damage ◽  
Organ Donor ◽  
Donation After Circulatory Death ◽  
Donation After Brain Death ◽  
Circulatory Death

Donation after Brain Death versus Donation after Circulatory Death: Lung Donor Management Issues

2018 ◽  
Vol 39 (02) ◽  
pp. 138-147 ◽  
Author(s):  
Bronwyn Levvey ◽  
Kovi Levin ◽  
Miranda Paraskeva ◽  
Glen Westall ◽  
Gregory Snell
Keyword(s):  
Brain Death ◽  
Ex Vivo ◽  
Scoring Systems ◽  
Donation After Circulatory Death ◽  
Donor Pool ◽  
Ex Vivo Lung Perfusion ◽  
Conversion Rates ◽  
Donor Lung ◽  
Donation After Brain Death ◽  
Circulatory Death

AbstractLung transplantation (LTx) has traditionally been limited by a lack of suitable donor lungs. With the recognition that lungs are more robust than initially thought, the size of the donor pool of available lungs has increased dramatically in the past decade. Donation after brain death (DBD) and donation after circulatory death (DCD) lungs, both ideal and extended are now routinely utilized. DBD lungs can be damaged. There are important differences in the public's understanding, legal and consent processes, intensive care unit strategies, lung pathophysiology, logistics, and potential-to-actual donor conversion rates between DBD and DCD. Notwithstanding, the short- and long-term outcomes of LTx from any of these DBD versus DCD donor scenarios are now similar, robust, and continue to improve. Large audits suggest there remains a large untapped pool of DCD (but not DBD) lungs that may yet further dramatically increase lung transplant numbers. Donor scoring systems that might predict the donor conversion rates and lung quality, the role of ex vivo lung perfusion as an assessment and lung resuscitation tool, as well as the potential of donor lung quality biomarkers all have immense promise for the clinical field.

Nitric oxide levels following perfusion differ in donation after circulatory death and donation after brain death transplants

2013 ◽  
Vol 95 (5) ◽  
pp. e10-e10
Author(s):  
R Johns ◽  
A Chaudry ◽  
E Khanafer ◽  
A Ilham ◽  
M Stephens ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Brain Death ◽  
Joint Meeting ◽  
Donation After Circulatory Death ◽  
Donation After Brain Death ◽  
Hilton Hotel ◽  
Transplantation Society ◽  
Circulatory Death

Affiliated to the Association of Surgeons in Training and the British Transplantation Society, the Carrel Club is the transplant trainee surgical society. The Carrel Club held a joint meeting with the Chapter of Transplant Surgeons, a subsidiary organisation of the British Transplantation Society, at the Manchester Hilton Hotel on 31 January and 1 February 2013. As part of the meeting, ten abstracts were presented. A selection is printed below. The winner of the Best Presentation award was Mr Mownah.

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