scholarly journals Randomized clinical trial of goal-directed fluid therapy within an enhanced recovery protocol for elective colectomy

2012 ◽  
Vol 100 (1) ◽  
pp. 66-74 ◽  
Author(s):  
S. Srinivasa ◽  
M. H. G. Taylor ◽  
P. P. Singh ◽  
T.-C. Yu ◽  
M. Soop ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Fluid Therapy ◽  
Enhanced Recovery ◽  
Goal Directed Fluid Therapy ◽  
Enhanced Recovery Protocol ◽  
Elective Colectomy

scholarly journals Enhanced Recovery Protocol After Hand-Assisted Laparoscopic Donor Nephrectomy: A Randomized Clinical Trial

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Alberts Victor P ◽  
Minnee Robert C ◽  
Bemelman Frederike J ◽  
Pant Karlijn AMI van der ◽  
Hollmann Markus W ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Enhanced Recovery ◽  
Donor Nephrectomy ◽  
Laparoscopic Donor Nephrectomy ◽  
Enhanced Recovery Protocol

Goal-directed Fluid Therapy Does Not Reduce Primary Postoperative Ileus after Elective Laparoscopic Colorectal Surgery

2017 ◽  
Vol 127 (1) ◽  
pp. 36-49 ◽  
Author(s):  
Juan C. Gómez-Izquierdo ◽  
Alessandro Trainito ◽  
David Mirzakandov ◽  
Barry L. Stein ◽  
Sender Liberman ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Fluid Therapy ◽  
Postoperative Ileus ◽  
Enhanced Recovery ◽  
Laparoscopic Colorectal Surgery ◽  
Enhanced Recovery After Surgery ◽  
Therapy Group ◽  
Control Group ◽  
Goal Directed Fluid Therapy ◽  
The Impact

Abstract Background Inadequate perioperative fluid therapy impairs gastrointestinal function. Studies primarily evaluating the impact of goal-directed fluid therapy on primary postoperative ileus are missing. The objective of this study was to determine whether goal-directed fluid therapy reduces the incidence of primary postoperative ileus after laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Methods Randomized patient and assessor-blind controlled trial conducted in adult patients undergoing laparoscopic colorectal surgery within an Enhanced Recovery After Surgery program. Patients were assigned randomly to receive intraoperative goal-directed fluid therapy (goal-directed fluid therapy group) or fluid therapy based on traditional principles (control group). Primary postoperative ileus was the primary outcome. Results One hundred twenty-eight patients were included and analyzed (goal-directed fluid therapy group: n = 64; control group: n = 64). The incidence of primary postoperative ileus was 22% in the goal-directed fluid therapy and 22% in the control group (relative risk, 1; 95% CI, 0.5 to 1.9; P = 1.00). Intraoperatively, patients in the goal-directed fluid therapy group received less intravenous fluids (mainly less crystalloids) but a greater volume of colloids. The increase of stroke volume and cardiac output was more pronounced and sustained in the goal-directed fluid therapy group. Length of hospital stay, 30-day postoperative morbidity, and mortality were not different. Conclusions Intraoperative goal-directed fluid therapy compared with fluid therapy based on traditional principles does not reduce primary postoperative ileus in patients undergoing laparoscopic colorectal surgery in the context of an Enhanced Recovery After Surgery program. Its previously demonstrated benefits might have been offset by advancements in perioperative care.

scholarly journals Restrictive versus Liberal Fluid Therapy for Post-Cesarean Acute Kidney Injury in Severe Preeclampsia: a Pilot Randomized Clinical Trial

Clinics ◽  
2020 ◽  
Vol 75 ◽  
Author(s):  
Wallace Andrino da Silva ◽  
Carlo Victor A. Varela ◽  
Aline Macedo Pinheiro ◽  
Paula Castro Scherer ◽  
Rossana P.V. Francisco ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Acute Kidney Injury ◽  
Randomized Clinical Trial ◽  
Fluid Therapy ◽  
Kidney Injury ◽  
Severe Preeclampsia
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