Second axillary sentinel node biopsy for ipsilateral breast tumour recurrence

2007 ◽  
Vol 94 (10) ◽  
pp. 1216-1219 ◽  
Author(s):  
M. Intra ◽  
G. Trifirò ◽  
V. Galimberti ◽  
O. Gentilini ◽  
N. Rotmensz ◽  
...  
Keyword(s):  
Sentinel Node ◽  
Sentinel Node Biopsy ◽  
Breast Tumour ◽  
Tumour Recurrence ◽  
Ipsilateral Breast ◽  
Node Biopsy ◽  
Ipsilateral Breast Tumour Recurrence

scholarly journals When can a second conservative approach be considered for ipsilateral breast tumour recurrence?

2007 ◽  
Vol 18 (3) ◽  
pp. 468-472 ◽  
Author(s):  
O. Gentilini ◽  
E. Botteri ◽  
N. Rotmensz ◽  
B. Santillo ◽  
N. Peradze ◽  
...  
Keyword(s):  
Breast Tumour ◽  
Tumour Recurrence ◽  
Conservative Approach ◽  
Ipsilateral Breast ◽  
Ipsilateral Breast Tumour Recurrence

scholarly journals Unavoidable mastectomy for ipsilateral breast tumour recurrence after conservative surgery: patient outcome

2009 ◽  
Vol 20 (6) ◽  
pp. 1008-1012 ◽  
Author(s):  
E. Botteri ◽  
N. Rotmensz ◽  
C. Sangalli ◽  
A. Toesca ◽  
N. Peradze ◽  
...  
Keyword(s):  
Patient Outcome ◽  
Conservative Surgery ◽  
Breast Tumour ◽  
Tumour Recurrence ◽  
Ipsilateral Breast ◽  
Surgery Patient ◽  
Ipsilateral Breast Tumour Recurrence

scholarly journals Repeat Breast-Conserving Surgery Versus Salvage Mastectomy for Ipsilateral Breast Tumour Recurrence After Breast-Conserving Surgery in Breast Cancer Patients: A Meta-Analysis

2021 ◽  
Vol 11 ◽  
Author(s):  
Caiqin Mo ◽  
Weihong Ruan ◽  
Junyu Lin ◽  
Huaying Chen ◽  
Xiangjin Chen
Keyword(s):  
Meta Analysis ◽  
Breast Conserving Surgery ◽  
Breast Tumour ◽  
Tumour Recurrence ◽  
Salvage Radiotherapy ◽  
Ipsilateral Breast ◽  
Radiotherapy Group ◽  
Significant Difference ◽  
Ipsilateral Breast Tumour Recurrence ◽  
Salvage Mastectomy

BackgroundSalvage mastectomy (SM) is the standard surgery for ipsilateral breast tumour recurrence (IBTR). However, whether repeat breast-conserving surgery (RBCS) is an alternative method remains unclear. We performed a meta-analysis to compare the effects of RBCS and SM after IBTR for breast-conserving surgery (BCS).MethodsWe searched PubMed, Cochrane, Wiley Online and Embase for controlled studies comparing RBCS and SM after IBTR for BCS (published between 1993 and 2019, published in English). Our main endpoints were the secondary local recurrence rate (SLRR), distant metastasis rate (DMR) and overall survival (OS). We used a random-effects model or fixed-effects model for data pooling.ResultsFifteen of the 424 eligible studies were ultimately included, and all studies were retrospective cohort studies (n=2532 participants). 1) SLRR: The SLRR of RBCS was higher than SM (pooled relative rate (pRR) = 1.87, 95% CI 1.22 - 2.86, P=0.004). Stratified analysis was performed according to whether radiotherapy was performed after salvage surgery (radiotherapy group: 2ndRT, no radiotherapy group: no-2ndRT), and the following results were revealed: pRR=0.43 (95% CI 0.20-0.95, P=0.04) for group 2ndRT; and pRR=2.30 (95% CI 1.72-3.06, P<0.00001) for group no-2ndRT. These results showed that the main cause of heterogeneity was salvage radiotherapy. 2) DMR: No significant difference in the DMR was observed between RBCS and SM (pRR = 0.61, 95% CI 0.37 - 1.01, P=0.05). 3) OS: No significant difference in OS was observed between RBCS and SM (pRR=0.65, 95% CI 0.39 - 1.08, P=0.10).ConclusionsThe SLRR of RBCS was higher than SM for ITBR after BCS, but survival was not affected. RBCS may be used as an alternative for IBTR patients after BCS with strict control for several indications, such as tumor size, recurrence interval and biological behavior, and attaching importance to subsequent salvage radiotherapy and systematic therapy.

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