Prospective study of carotid endarterectomy and contralateral carotid occlusion

1996 ◽  
Vol 83 (10) ◽  
pp. 1370-1372 ◽  
Author(s):  
A. F. Da Silva ◽  
P. McCollum ◽  
T. Szymanska ◽  
L. De Cossart
1998 ◽  
Vol 88 (4) ◽  
pp. 892-897 ◽  
Author(s):  
Robert E. Grady ◽  
Margaret R. Weglinski ◽  
Frank W. Sharbrough ◽  
William J. Perkins

Background Carotid endarterectomy necessitates temporary unilateral carotid artery occlusion. Critical regional cerebral blood flow (rCBF) has been defined as the rCBF below which electroencephalographic (EEG) changes of ischemia occur. This study determined the rCBF50, the rCBF value at which 50% of patients will not demonstrate EEG evidence of cerebral ischemia with carotid cross-clamping. Methods Fifty-two patients undergoing elective carotid endarterectomy were administered 0.6-1.2% (0.3-0.6 minimum alveolar concentration) sevoflurane in 50% nitrous oxide (N2O). A 16-channel EEG was used for monitoring. The washout curves from intracarotid 133Xenon injections were used to calculate rCBF before and at the time of carotid occlusion by the half-time (t(1/2)) technique. The quality of the EEG with respect to ischemia detection was assessed by an experienced electroencephalographer. Results Ischemic EEG changes developed in 5 of 52 patients within 3 min of carotid occlusion at rCBFs of 7, 8, 11, 11, and 13 ml x 100 g(-1) x min(-1). Logistic regression analysis was used to calculate an rCBF50 of 11.5 +/- 1.4 ml x 100 g(-1) x min(-1) for sevoflurane. The EEG signal demonstrated the necessary amplitude, frequency, and stability for the accurate detection of cerebral ischemia in all patients within the range of 0.6-1.2% sevoflurane in 50% N2O. Conclusions The rCBF50 of 0.6-1.2% sevoflurane in 50% N2O, as determined using logistic regression analysis, is 11.5 +/- 1.4 ml 100 g(-1) x min(-1). Further, in patients anesthetized in this manner, ischemic EEG changes due to carotid occlusion were accurately and rapidly detected.


1986 ◽  
Vol 14 (1) ◽  
pp. 32-36 ◽  
Author(s):  
A. B. Baker ◽  
A. J. Roxburgh

A prospective study was undertaken in twenty patients undergoing carotid endarterectomy using computerised EEG monitoring in the form of a density-modulated spectral array, spectral edge frequency and integrated EEG power for monitoring cerebral ischaemia. This form of monitoring proved to be easy to use and understand. Because ischaemic EEG events longer than one minute were not necessarily followed by postoperative deficits, the definition of significant events that would cause ischaemia may need to be modified.


Vascular ◽  
2019 ◽  
Vol 27 (6) ◽  
pp. 595-603 ◽  
Author(s):  
Wen-Qiang Xin ◽  
Yan Zhao ◽  
Tie-Zhu Ma ◽  
Yi-Kuan Gao ◽  
Wei-Han Wang ◽  
...  

Objectives The purpose of this study was to conduct a meta-analysis to systematically compare the safety and efficacy of carotid endarterectomy and carotid artery stenting in contralateral carotid occlusion patients who needed reperfusion. Methods This study retrieved potential academic articles comparing results between carotid endarterectomy and carotid artery stenting for patients with contralateral carotid occlusion from the MEDLINE database, the PubMed database the EMBASE database, and the Cochrane Library from January 1990 to May 2018. The reference articles for the identified studies were carefully reviewed to ensure that all available documents were represented in the study. Results Four retrospective cohort study involving 6252 patients with contralateral carotid occlusion were included in our meta-analysis. During 30-day follow-up, there is significant difference in post-procedure mortality (odds ratio (OR) = 0.476, 95% confidence interval (CI) (0.306–0.740), P = 0.001); no significant differences are not found in post-procedure stroke (risk difference (RD) = 0.002, 95%CI (–0.007 to 0.011); P = 0.631), myocardial infarction (RD = 0.003, 95%CI (–0.002 to 0.008); P = 0.301), and transient cerebral ischemia (RD = 1.059, 95%CI (–0.188 to 5.964); P = 0.948). Conclusions Carotid endarterectomy was associated with a lower incidence of mortality compared to carotid artery stenting for patients with contralateral carotid occlusion. Regarding stroke, myocardial infarction, and transient ischemic attack, there was no significant difference between the two groups. More randomized controlled trials and prospective cohorts are necessary to help further clarify the ideal approach for these patients.


2005 ◽  
Vol 41 (5) ◽  
pp. 789-793 ◽  
Author(s):  
Ali F. AbuRahma ◽  
Patrick A. Stone ◽  
Christine A. Welch ◽  
Matthew J. Hofeldt ◽  
Stephen M. Hass ◽  
...  

2017 ◽  
Vol 23 (5) ◽  
pp. 227-232 ◽  
Author(s):  
Jie Kong ◽  
Jinyong Li ◽  
Zhidong Ye ◽  
Xueqiang Fan ◽  
Jianyan Wen ◽  
...  

1997 ◽  
Vol 84 (4) ◽  
pp. 585-586
Author(s):  
A. J. McCleary ◽  
A. F. Da Silva ◽  
P. McCollum ◽  
T. Szymanska ◽  
L. De Cossart

2001 ◽  
Vol 34 (3) ◽  
pp. 532-540 ◽  
Author(s):  
Masaaki Uno ◽  
Fusamitsu Hamazaki ◽  
Takeshi Kohno ◽  
Akira Sebe ◽  
Hidehisa Horiguchi ◽  
...  

1994 ◽  
Vol 19 (1) ◽  
pp. 15-22 ◽  
Author(s):  
Stuart I. Myers ◽  
R.James Valentine ◽  
Arun Chervu ◽  
Benjamin L. Bowers ◽  
G.Patrick Clagett

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