Rectal cancer risk in patients treated for familial adenomatous polyposis

1993 ◽  
Vol 80 (6) ◽  
pp. 808-808
Author(s):  
F. Seow-Choen ◽  
A. F. P. K. Leong ◽  
T. A. Teoh
Keyword(s):  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Cancer Risk ◽  
Adenomatous Polyposis

Rectal cancer risk in patients treated for familial adenomatous polyposis

1992 ◽  
Vol 79 (12) ◽  
pp. 1372-1375 ◽  
Author(s):  
J. J. De Cosse ◽  
S. Bülow ◽  
K. Neale ◽  
H. Järvinen ◽  
T. Alm ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Cancer Risk ◽  
Adenomatous Polyposis

scholarly journals Surgical complications and metachronous rectal cancer risk in patients with classic familial adenomatous polyposis

2015 ◽  
Vol 35 (1) ◽  
pp. 8-13
Author(s):  
Paulo Roberto Stevanato Filho ◽  
Samuel Aguiar ◽  
Fábio O. Ferreira ◽  
Wilson T. Nakagawa ◽  
Ranyell M. Spencer ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Cancer Risk ◽  
Surgical Complications ◽  
Adenomatous Polyposis ◽  
Metachronous Rectal Cancer

scholarly journals A Support Vector Machine Model Predicting the Risk of Duodenal Cancer in Patients with Familial Adenomatous Polyposis at the Transcript Levels

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Weiqing Liu ◽  
Jian Dong ◽  
Shumin Ma ◽  
Lei Liang ◽  
Jun Yang
Keyword(s):  
Support Vector Machine ◽  
Familial Adenomatous Polyposis ◽  
Cancer Risk ◽  
Prediction Model ◽  
Differentially Expressed Genes ◽  
Differentially Expressed ◽  
Duodenal Cancer ◽  
Support Vector ◽  
Adenomatous Polyposis ◽  
Transcript Levels

Objective. Familial adenomatous polyposis (FAP) is one major type of inherited duodenal cancer. The estimate of duodenal cancer risk in patients with FAP is critical for selecting the optimal treatment strategy. Methods. Microarray datasets related with FAP were retrieved from the Gene Expression Omnibus (GEO) database. Differentially expressed genes were identified by FAP vs. normal samples and FAP and duodenal cancer vs. normal samples. Furthermore, functional enrichment analyses of these differentially expressed genes were performed. A support vector machine (SVM) was performed to train and validate cancer risk prediction model. Results. A total of 196 differentially expressed genes were identified between FAP compared with normal samples. 177 similarly expressed genes were identified both in FAP and duodenal cancer, which were mainly enriched in pathways in cancer and metabolic-related pathway, indicating that these genes in patients with FAP could contribute to duodenal cancer. Among them, Cyclin D1, SDF-1, AXIN, and TCF were significantly upregulated in FAP tissues using qRT-PCR. Based on the 177 genes, an SVM model was constructed for prediction of the risk of cancer in patients with FAP. After validation, the model can accurately distinguish FAP patients with high risk from those with low risk for duodenal cancer. Conclusion. This study proposed a cancer risk prediction model based on an SVM at the transcript levels.

Attenuated Familial Adenomatous Polyposis Associated with Advanced Rectal Cancer in a 16-Year-Old Boy: Report of a Case

Surgery Today ◽  
2001 ◽  
Vol 31 (11) ◽  
pp. 1020-1023 ◽  
Author(s):  
Shigetoshi Matsuo ◽  
Susumu Eguchi ◽  
Takashi Azuma ◽  
Masaaki Hidaka ◽  
Satoshi Yamaguchi ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Advanced Rectal Cancer ◽  
Adenomatous Polyposis ◽  
Attenuated Familial Adenomatous Polyposis

Risk of Rectal Cancer in Patients After Colectomy and Ileorectal Anastomosis for Familial Adenomatous Polyposis

2003 ◽  
Vol 46 (9) ◽  
pp. 1175-1181 ◽  
Author(s):  
James Church ◽  
Carol Burke ◽  
Ellen McGannon ◽  
Olivia Pastean ◽  
Bryan Clark
Keyword(s):  
Rectal Cancer ◽  
Familial Adenomatous Polyposis ◽  
Ileorectal Anastomosis ◽  
Adenomatous Polyposis
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