Randomized study of adjusted versus fixed low dose heparin prophylaxis of deep vein thrombosis in hip surgery

1989 ◽  
Vol 76 (9) ◽  
pp. 933-935 ◽  
Author(s):  
D. A. Taberner ◽  
L. Poller ◽  
J. M. Thomson ◽  
G. Lemon ◽  
F. J. Weighill
Keyword(s):  
Deep Vein Thrombosis ◽  
Low Dose ◽  
Randomized Study ◽  
Hip Surgery ◽  
Vein Thrombosis ◽  
Dose Heparin ◽  
Deep Vein ◽  
Low Dose Heparin ◽  
Heparin Prophylaxis

LOW-DOSE HEPARIN PROPHYLAXIS AGAINST DEEP-VEIN THROMBOSIS AFTER ACUTE STROKE

The Lancet ◽  
1978 ◽  
Vol 311 (8056) ◽  
pp. 160-161
Author(s):  
O.J.S. Buruma ◽  
A.R. Wintzen ◽  
E. Briët
Keyword(s):  
Deep Vein Thrombosis ◽  
Acute Stroke ◽  
Low Dose ◽  
Vein Thrombosis ◽  
Dose Heparin ◽  
Deep Vein ◽  
Low Dose Heparin ◽  
Heparin Prophylaxis

Deep vein thrombosis and low-dose heparin prophylaxis in neurosurgical patients

1978 ◽  
Vol 49 (3) ◽  
pp. 378-381 ◽  
Author(s):  
Dario Cerrato ◽  
Cesare Ariano ◽  
Folco Fiacchino
Keyword(s):  
Deep Vein Thrombosis ◽  
Low Dose ◽  
Motor Deficit ◽  
Control Group ◽  
Heparin Group ◽  
Vein Thrombosis ◽  
Dose Heparin ◽  
Deep Vein ◽  
Low Dose Heparin ◽  
Heparin Prophylaxis

✓ By the use of 125I-labeled fibrinogen test, the incidence of postoperative deep vein thrombosis (DVT) and the effectiveness of prophylactic low-dose heparin treatment were investigated in 110 patients who underwent elective neurosurgical procedures. Fifty patients were appointed randomly to a control group and 50 to a heparin group (10 patients were excluded since they had DVT before surgery). The incidence of DVT was reduced from 34% in the control group to 6% in the heparin group (p < 0.005). No statistically significant differences were observed in transfusion requirements, postoperative hemoglobin concentration, and the occurrence of postoperative hematomas between the two groups. Positive correlation was observed between DVT and motor deficit (p < 0.05). Preoperative assessment of patients' sensitivity to the standard 5000-unit dose of heparin was performed in all treated patients and is thought an important factor in improving the safety of heparin prophylaxis.

Low-Dose Heparin and Deep-Vein Thrombosis after Total Hip Replacement

1976 ◽  
Vol 36 (01) ◽  
pp. 157-164 ◽  
Author(s):  
P. M Mannucci ◽  
Luisa E. Citterio ◽  
N Panajotopoulos
Keyword(s):  
Deep Vein Thrombosis ◽  
Total Hip Replacement ◽  
Hip Replacement ◽  
Low Dose ◽  
Control Group ◽  
Total Hip ◽  
Vein Thrombosis ◽  
Dose Heparin ◽  
Deep Vein ◽  
Low Dose Heparin

SummaryThe effect of subcutaneous low-dose heparin on postoperative deep-vein thrombosis (D. V. T.) (diagnosed by the 125I-labelled fibrinogen test) has been investigated in a trial of 143 patients undergoing the operation of total hip replacement. Two randomized studies were carried out: in one the scanning for D.V.T. was carried out daily for 7 days post operatively and in the other for 15 days. In both, the incidence of D.V.T. was significantly lower in the heparin-treated patients (P<0.005). Bilateral D.V.T. was also prevented (P<0.05), through the extension of D.V.T. to the distal veins of the thigh was not significantly reduced. Heparin treatment was, however, followed by a higher incidence of severe postoperative bleeding (P< 0.02) and wound haematoma formation (P< 0.005), and the postoperative haemoglobin was significantly lower than in the control group (P<0.005). A higher number of transfused blood units was also needed by the heparin treated patients (P<0.001).

The Prophylaxis of Deep Vein Thrombosis with Low-Dose Heparin: A Trial

1974 ◽  
Vol 44 (3) ◽  
pp. 289-291 ◽  
Author(s):  
J. Propsting ◽  
O. Williams ◽  
M. Stathis ◽  
J. F. Mccaffrey
Keyword(s):  
Deep Vein Thrombosis ◽  
Low Dose ◽  
Vein Thrombosis ◽  
Dose Heparin ◽  
Deep Vein ◽  
Low Dose Heparin

Low-Dose Heparin in Proximal Femoral Fractures:Failure to Prevent Deep-Vein Thrombosis

1981 ◽  
Vol 52 (1) ◽  
pp. 77-80 ◽  
Author(s):  
H. Svend-Hansen ◽  
V. Bremerskov ◽  
J. Gøtrich ◽  
P. Ostri
Keyword(s):  
Deep Vein Thrombosis ◽  
Low Dose ◽  
Vein Thrombosis ◽  
Dose Heparin ◽  
Deep Vein ◽  
Low Dose Heparin
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