scholarly journals Risk of local recurrence of rectal cancer and circumferential resection margin: population-based cohort study

2020 ◽  
Vol 107 (5) ◽  
pp. 580-585 ◽  
Author(s):  
E. A. Agger ◽  
F. H. Jörgren ◽  
M.-L. A. Lydrup ◽  
P. L. Buchwald
Keyword(s):  
Rectal Cancer ◽  
Cohort Study ◽  
Local Recurrence ◽  
Circumferential Resection Margin ◽  
Resection Margin ◽  
Population Based ◽  
Recurrence Of Rectal Cancer

Pathology Studies of Combined Radical Resection of Seminal Vesicle in the Treatment of Rectal Cancer

2011 ◽  
Vol 96 (1) ◽  
pp. 51-55 ◽  
Author(s):  
Koji Komori ◽  
Takashi Hirai ◽  
Yukihide Kanemitsu ◽  
Yasuhiro Shimizu ◽  
Tsuyoshi Sano ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Local Recurrence ◽  
Seminal Vesicle ◽  
Circumferential Resection Margin ◽  
Resection Margin ◽  
Radical Resection ◽  
Seminal Vesicles ◽  
Recurrence Of Rectal Cancer

Abstract To inhibit local recurrence of rectal cancer, it is very important to ensure that there is a sufficient circumferential resection margin. We evaluated pathology studies of combined radical resection of seminal vesicles in the treatment of rectal cancer. We analyzed data from 7 cases of combined radical resection of the seminal vesicle in the treatment of rectal cancer; we also analyzed data from 35 control cases without seminal vesicle resection. The circumferential resection margin averaged 5.97 mm for cases that had combined radical resection of the seminal vesicle, and this was significantly longer than for cases without resection (P < 0.001). Local recurrence was not seen in cases that had combined radical resection of the seminal vesicle, whereas 3 cases (5.9%) occurred in the group that did not undergo resection. Combined radical resection of the seminal vesicle in patients with rectal cancer ensures that the distance of the circumferential resection margin is sufficient to inhibit local recurrence.

The Prognostic Value of Circumferential Resection Margin Involvement in Patients with Extraperitoneal Rectal Cancer

2016 ◽  
Vol 82 (4) ◽  
pp. 348-355 ◽  
Author(s):  
Dong Woo Shin ◽  
Jin Yong Shin ◽  
Sung Jin Oh ◽  
Jong Kwon Park ◽  
Hyeon Yu ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Local Recurrence ◽  
Circumferential Resection Margin ◽  
Resection Margin ◽  
Cox Model ◽  
Prognostic Significance ◽  
Multivariate Logistic Regression Analysis ◽  
T3 Rectal Cancer ◽  
Circumferential Resection Margin Involvement ◽  
Cox Analysis

The prognostic influence of circumferential resection margin (CRM) status in extraperitoneal rectal cancer probably differs from that of intraperitoneal rectal cancer because of its different anatomical and biological behaviors. However, previous reports have not provided the data focused on extraperitoneal rectal cancer. Therefore, the aim of this study was to examine the prognostic significance of the CRM status in patients with extraperitoneal rectal cancer. From January 2005 to December 2008, 248 patients were treated for extraperitoneal rectal cancer and enrolled in a pro-spectively collected database. Extraperitoneal rectal cancer was defined based on tumors located below the anterior peritoneal reflection, as determined intraoperatively by a surgeon. Cox model was used for multivariate analysis to examine risk factors of recurrence and mortality in the 248 patients, and multivariate logistic regression analysis was performed to identify predictors of recurrence and mortality in 135 patients with T3 rectal cancer. CRM involvement for extraperitoneal rectal cancer was present in 29 (11.7%) of the 248 patients, and was the identified predictor of local recurrence, overall recurrence, and death by multivariate Cox analysis. In the 135 patients with T3 cancer, CRM involvement was found to be associated with higher probability of local recurrence and mortality. In extraperitoneal rectal cancer, CRM involvement is an independent risk factor of recurrence and survival. Based on the results of the present study, it seems that CRM involvement in extraperitoneal rectal cancer is considered an indicator for (neo)adjuvant therapy rather than conventional TN status.

scholarly journals Oncologic superiority of extralevator abdominoperineal excision for low rectal cancer

2013 ◽  
Vol 21 (1) ◽  
pp. 11-13
Author(s):  
Dejan Lukic ◽  
Zoran Radovanovic ◽  
Tomislav Petrovic ◽  
Milan Breberina ◽  
Andrija Golubovic ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Local Recurrence ◽  
Circumferential Resection Margin ◽  
Resection Margin ◽  
Abdominoperineal Excision ◽  
Low Rectal Cancer ◽  
Margin Involvement ◽  
Radio Therapy ◽  
Circumferential Resection Margin Involvement ◽  
Prone Jackknife Position

Background: Rectal cancer treatment has been dramatically improved during the last two decades in terms of a lower local recurrence rate and prolonged survival. This improvement was achieved mainly due to a better surgical technique (implementation of a total mesorectal excision-TME) and neoadjuvant chemo and radio therapy. A more radical approach to abdominoperineal excision, extralevator abdominoperineal excision technique in the prone Jackknife position, may improve the oncological outcome. The aim of this study is to show our early experience by using extralevator abdominoperineal excision. Methods: Extralevator abdominoperineal excision has been used routinely at Oncology Institute of Vojvodina since 2011. In the last 23 months, we had 11 operations. Clinical and pathological data were obtained from operative protocols, histopathological data and patients? medical history. Results: An audit of results showed reduced rate of intra-operative perforations and circumferential resection margin involvement. Late postoperative complications have occurred in two patients, sexual dysfunction in one and pelvic pain in the other. The follow up period is too short (min 2 months, max 23 months, median 8 months) for analysis of local recurrence. Conclusion: Extralevator abdominoperineal excision, with the emphasis on the perienal dissection and prone Jackknife position, may help achieve the goals of radical resections for low rectal cancer. This technique could be associated with less intra-operative perforations and circumferential resection margin involvement.

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