scholarly journals Long-term functional outcomes and quality of life in patients with Hirschsprung's disease

2019 ◽  
Vol 106 (4) ◽  
pp. 499-507 ◽  
Author(s):  
R. J. Meinds ◽  
A. F. W. van der Steeg ◽  
C. E. J. Sloots ◽  
M. J. Witvliet ◽  
I. de Blaauw ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Functional Outcomes ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease

Long-Term Outcomes and Quality of Life in Patients after Soave Pull-Through Operation for Hirschsprung's Disease: An Observational Retrospective Study

2017 ◽  
Vol 28 (05) ◽  
pp. 445-454 ◽  
Author(s):  
Tania Mahler ◽  
Martine Dassonville ◽  
Dinh Truong ◽  
Annie Robert ◽  
Philippe Goyens ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Fecal Incontinence ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Bowel Function ◽  
Long Term Outcomes ◽  
Neurologic Impairment ◽  
Pull Through

Introduction Patients after pull-through operation for Hirschsprung's disease (HD) are at high risk of defecation disorders. This study aimed at investigating their long-term outcomes and quality of life (QoL) in comparison with controls. Patients and Methods Patients older than 5 years operated on for HD were interviewed to complete detailed questionnaires on bowel function. Patients without neurologic impairment were enrolled in a QoL survey to compare with controls matched for sex and age and selected randomly from the general population using sampling set in a ratio of four controls to one case of HD. Results In total, 53 operated patients were enrolled. Mean age of the patients was 16 ± 8 years, with 68% boys. Rectosigmoid aganglionosis was the most seen form of HD in 38 (72%) cases. Open Soave was performed in 40 (75.5%) cases, and minimally invasive surgery Soave (MIS Soave) in 13 (24.5%) cases. At investigation, prevalence of fecal incontinence and constipation were 22.6 and 13.2%, respectively. Regarding QoL survey, 45 patients and 180 controls were enrolled, excluding 8 patients with neurologic impairment. Thirty-seven (82.2%) patients were classified as having a good QoL (score ≥ 9 points); whereas six had a fair QoL (5–8 points) and two had a poor QoL (< 5 points). QoL score in the cases and the controls were 10.2 ± 2.5 and 11.9 ± 0.4 points, respectively. Long aganglionosis form of HD was significantly associated with a low QoL (score < 8 points), adjusted odds ratio = 9, 95% confidence interval [1.3; 64.1] (p < 0.05). In subscales analyses, the prevalence of each dimension including fecal continence, school absenteeism, unhappiness or anxiety, food restriction, and peer rejection was significantly higher in operated patients than in controls (p <0.001). Conclusion Although the QoL of patients operated on for HD in general was with good outcomes, fecal incontinence and constipation still are problematic issues and challenges in a high percentage of patients. Therefore, a long-term and multidisciplinary follow-up is essentially required for these patients.

Long-term outcome and quality of life after the Swenson procedure for Hirschsprung's disease

2002 ◽  
Vol 37 (4) ◽  
pp. 639-642 ◽  
Author(s):  
YuZuo Bai ◽  
Hui Chen ◽  
Jing Hao ◽  
Ying Huang ◽  
WeiLin Wang
Keyword(s):  
Quality Of Life ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Term Outcome ◽  
Long Term Outcome

Long-term bowel function and quality of life in children with Hirschsprung's disease

2008 ◽  
Vol 43 (5) ◽  
pp. 899-905 ◽  
Author(s):  
Jessica L.A. Mills ◽  
David E. Konkin ◽  
Ruth Milner ◽  
Janice G. Penner ◽  
Monica Langer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Bowel Function

Social Morbidity in Relation to Bowel Functional Outcomes and Quality of Life in Anorectal Malformations and Hirschsprung's Disease

2017 ◽  
Vol 28 (06) ◽  
pp. 522-528 ◽  
Author(s):  
Malla Neuvonen ◽  
Mikko Pakarinen ◽  
Risto Rintala ◽  
Kristiina Kyrklund
Keyword(s):  
Quality Of Life ◽  
Functional Outcomes ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Social Problems ◽  
Bowel Function ◽  
Anorectal Malformations ◽  
Minimal Risk ◽  
The Social

Background Anorectal malformations (ARMs) and Hirschsprung's disease (HD) are chronic bowel conditions associated with varying degrees of fecal incontinence. We aimed to discuss the contemporary status of social morbidity associated with ARMs and HD in the long term after contemporary treatments. Materials and Methods The bowel functional outcomes of our recent institutional series up to adulthood were reviewed and compared for ARMs and HD. The Rintala score was used to evaluate bowel function, which includes an assessment of the social effects of the condition. In this study, the social outcomes in our population of patients with ARMs and HD were specifically analyzed in relation to the surveyed functional outcomes, our previously collected data on quality of life (QoL) and the current literature. Results Mild ARMs were associated with a minimal risk of social morbidity consistent with good outcomes. In severe ARMs and HD, social problems were reported steadily among all age groups studied. Impairment of domains of fecal control were present among 53 to 89% of patients with social problems, including frequent symptoms (>1/week) in up to 39%. Involuntary gas leakage contributed to social morbidity in 15 to 27%. Comparison with QoL data suggested that social morbidity experienced during childhood may continue to affect emotional domains of QoL in later life, despite improvements in bowel function by adulthood. Conclusion Patients with severe ARMs and HD are at risk of social restrictions from impairment of bowel function despite contemporary surgical treatments. However, the QoL outcomes in adulthood may be more influenced by self-perceptions of illness formed from childhood than disease-specific factors. Strategies to reduce the psychological morbidity associated with these conditions that includes parental involvement from the outset may improve outcomes.

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