Viral adventitious agent detection using Laser Force Cytology: Intrinsic cell property changes with infection and comparison to in vitro testing

2021 ◽  
Author(s):  
Peter R. Hayes ◽  
Todd Przybycien ◽  
James W. Schneider
Keyword(s):  
In Vitro Testing ◽  
Cell Property ◽  
Property Changes

Urokinase Evaluated with the Experimental Radioactive Embolus

1967 ◽  
Vol 17 (03/04) ◽  
pp. 405-411
Author(s):  
M Hume
Keyword(s):  
Animal Experiment ◽  
Blood Clot ◽  
In Vitro Testing ◽  
Effective Agent

SummaryUrokinase and urokinase-activated plasmin have been given to the dog and rabbit. A thrombolytic state has been induced. Purified urokinase has induced lysis of the experimental radioactive blood clot embolus in the circulation. Demonstration of effectiveness in this animal experiment is hampered by inhibition of the agents in the circulation to a degree much greater than was noted in previous experiments with streptokinase. In vitro testing indicates that under proper conditions urokinase will be an effective agent in the treatment of human thromboembolism.

scholarly journals Syringeal vocal folds do not have a voice in zebra finch vocal development

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Alyssa Maxwell ◽  
Iris Adam ◽  
Pernille S. Larsen ◽  
Peter G. Sørensen ◽  
Coen P. H. Elemans
Keyword(s):  
Zebra Finch ◽  
Neural Circuit ◽  
Vocal Folds ◽  
Pressure Control ◽  
The Body ◽  
Vocal Development ◽  
Postnatal Maturation ◽  
Song System ◽  
Property Changes

AbstractVocal behavior can be dramatically changed by both neural circuit development and postnatal maturation of the body. During song learning in songbirds, both the song system and syringeal muscles are functionally changing, but it is unknown if maturation of sound generators within the syrinx contributes to vocal development. Here we densely sample the respiratory pressure control space of the zebra finch syrinx in vitro. We show that the syrinx produces sound very efficiently and that key acoustic parameters, minimal fundamental frequency, entropy and source level, do not change over development in both sexes. Thus, our data suggest that the observed acoustic changes in vocal development must be attributed to changes in the motor control pathway, from song system circuitry to muscle force, and not by material property changes in the avian analog of the vocal folds. We propose that in songbirds, muscle use and training driven by the sexually dimorphic song system are the crucial drivers that lead to sexual dimorphism of the syringeal skeleton and musculature. The size and properties of the instrument are thus not changing, while its player is.

In vitro testing of a first-in-class tri-alkylnorspermidine-biaryl antibiotic in an anti-biofilm silicone coating

2019 ◽  
Vol 93 ◽  
pp. 25-35 ◽  
Author(s):  
Nicholas N. Ashton ◽  
Gina Allyn ◽  
Scott T. Porter ◽  
Travis J. Haussener ◽  
Paul R. Sebahar ◽  
...  
Keyword(s):  
In Vitro Testing ◽  
Silicone Coating

In vivo and in vitro testing of gloves for protection against UV-curable acrylate resin systems

1984 ◽  
Vol 11 (5) ◽  
pp. 279-282 ◽  
Author(s):  
Robert L. Rietschel ◽  
Ronald Muggins ◽  
Nicole Levy ◽  
Pat M. Pruitt
Keyword(s):  
In Vitro Testing ◽  
Uv Curable ◽  
Acrylate Resin
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