A Novel Approach to Residence Time Distribution Characterization in a mAb Continuous Process

2021 ◽  
Author(s):  
Tim Brantley ◽  
Jon Bogue ◽  
Kurtis Denny ◽  
Sanaa Elouafiq ◽  
Seth Madren ◽  
...  
Keyword(s):  
Residence Time ◽  
Time Distribution ◽  
Residence Time Distribution ◽  
Continuous Process ◽  
Novel Approach

scholarly journals A novel technique for residence time distribution (RTD) measurements in solids unit operations

2021 ◽  
Vol 32 (2) ◽  
pp. 611-618
Author(s):  
Atena Dehghani Kiadehi ◽  
Mikel Leturia ◽  
Franco Otaola ◽  
Aissa Ould-Dris ◽  
Khashayar Saleh
Keyword(s):  
Residence Time ◽  
Time Distribution ◽  
Residence Time Distribution ◽  
Novel Technique ◽  
Unit Operations

scholarly journals Effects of Salt Tracer Volume and Concentration on Residence Time Distribution Curves for Characterization of Liquid Steel Behavior in Metallurgical Tundish

Metals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 430
Author(s):  
Changyou Ding ◽  
Hong Lei ◽  
Hong Niu ◽  
Han Zhang ◽  
Bin Yang ◽  
...  
Keyword(s):  
Residence Time ◽  
Time Distribution ◽  
Residence Time Distribution ◽  
Mass Concentration ◽  
Distribution Curve ◽  
Navier Stokes ◽  
Navier Stokes Equation ◽  
Residence Time Distribution Curve ◽  
Tracer Solution ◽  
Time Distribution Curve

The residence time distribution (RTD) curve is widely applied to describe the fluid flow in a tundish, different tracer mass concentrations and different tracer volumes give different residence time distribution curves for the same flow field. Thus, it is necessary to have a deep insight into the effects of the mass concentration and the volume of tracer solution on the residence time distribution curve. In order to describe the interaction between the tracer and the fluid, solute buoyancy is considered in the Navier–Stokes equation. Numerical results show that, with the increase of the mass concentration and the volume of the tracer, the shape of the residence time distribution curve changes from single flat peak to single sharp peak and then to double peaks. This change comes from the stratified flow of the tracer. Furthermore, the velocity difference number is introduced to demonstrate the importance of the density difference between the tracer and the fluid.

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