Simulation of pH level distribution inside a coiled flow inverter for continuous low pH viral inactivation

2019 ◽  
Vol 117 (2) ◽  
pp. 429-437 ◽  
Author(s):  
Laura David ◽  
Lisa Marie Waldschmidt ◽  
Martin Lobedann ◽  
Gerhard Schembecker
Keyword(s):  
Low Ph ◽  
Viral Inactivation ◽  
Ph Level

Design of a novel continuous flow reactor for low pH viral inactivation

2017 ◽  
Vol 115 (3) ◽  
pp. 606-616 ◽  
Author(s):  
Stephanie A. Parker ◽  
Linus Amarikwa ◽  
Kevin Vehar ◽  
Raquel Orozco ◽  
Scott Godfrey ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Flow Reactor ◽  
Low Ph ◽  
Viral Inactivation ◽  
Continuous Flow Reactor

Retrospective Evaluation of Low-pH Viral Inactivation and Viral Filtration Data from a Multiple Company Collaboration

2016 ◽  
Vol 70 (3) ◽  
pp. 293-299 ◽  
Author(s):  
J. Mattila ◽  
M. Clark ◽  
S. Liu ◽  
J. Pieracci ◽  
T. R. Gervais ◽  
...  
Keyword(s):  
Low Ph ◽  
Retrospective Evaluation ◽  
Viral Inactivation

Continuous viral inactivation at low pH value in antibody manufacturing

2016 ◽  
Vol 102 ◽  
pp. 88-101 ◽  
Author(s):  
Stephan Klutz ◽  
Martin Lobedann ◽  
Christian Bramsiepe ◽  
Gerhard Schembecker
Keyword(s):  
Ph Value ◽  
Low Ph ◽  
Viral Inactivation

scholarly journals Protein aggregation and mitigation strategy in low pH viral inactivation for monoclonal antibody purification

mAbs ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1479-1491 ◽  
Author(s):  
Weixin Jin ◽  
Zizhuo Xing ◽  
Yuanli Song ◽  
Chao Huang ◽  
Xuankuo Xu ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Protein Aggregation ◽  
Low Ph ◽  
Mitigation Strategy ◽  
Viral Inactivation ◽  
Antibody Purification

scholarly journals The Effect Of Giving Honey on The Process of Wound Healing in Burned Patients

2021 ◽  
Vol 5 (1) ◽  
pp. 51-56
Author(s):  
Intan Pramesty
Keyword(s):  
Staphylococcus Aureus ◽  
Wound Healing ◽  
Healing Process ◽  
Health Sector ◽  
Antimicrobial Properties ◽  
High Viscosity ◽  
Low Ph ◽  
Wound Healing Process ◽  
Burn Patients ◽  
Ph Level

Backgroud: Burns are one of the most dangerous injuries and the main cause of disability to death. Burns can be interpreted as one of the serious problems in society and are recorded to cause around 265,000 deaths each year. Honey can maintain the wound condition to keep it moist and in high viscosity to prevent infection. Method: This study was conducted to determine the effect of honey on the wound healing process in burn patients. This study uses a literature review method. The population in this study is a journal with a background in the health sector with 10 international journals on burns with the qualifications of 9 SCIMAGO indexed journals and 1 SINTA indexed journal published from 2015 to 2020. Results: Burns that treated in the form of pure honey can generate good results and heal in an average of 20 days. The healing process will be better, if the wound given a mixture of other ingredients which also have a low acidity such as garlic, chitosan and beeswax and olive oil. Honey has antimicrobial properties and a low pH level. The microbe most sensitive to honey is Staphylococcus aureus. Conclusion: The conclusion from this study, honey can be used as an alternative treatment for burns.

scholarly journals Acellular probiotics and asparagic acid in the prevention of postpartum endometritis in cows

2020 ◽  
pp. 14-20
Author(s):  
P. Krasochko ◽  
T. Snitko
Keyword(s):  
Lactic Acid ◽  
Aspartic Acid ◽  
Uterine Cavity ◽  
Animal Husbandry ◽  
Low Ph ◽  
Stress Factors ◽  
Acid Complex ◽  
Local Immunity ◽  
Fermentation Products ◽  
Ph Level

Postpartum endometritis is one of the most widespread pathologies in animal husbandry. They often occur on the background of exposure on animals stress factors, microclimate disorders, complete feeding, which is accompanied by decrease of the resistance, leads to increasing morbidity, etc. The aim of the research is to develop a method of prevention of postpartum endometritis in cows using cell-free probiotics "Bacinil" and "Lactimet" with 4 % suspension of aspartic acid. Complex use of integrated cell-free probiotics "Bacinyl" and "Lactimet" with 4% suspension of asparagic acid for the prevention of postpartum endometritis in doses of 7.5 and 10 ml each at 3-fold use once a day for 3 days in a row allowed to obtain 100% preventive efficacy. The mechanism of action of probiotic "Bacinil" is based on the high activity of components of its composition - immunostimulants (lipopolysaccharides), bacteriocins and enzymes, probiotic "Lactimet" due to biosynthetic lactic acid and a complex of fermentation products. Complex application of probiotics and aspartic acid increases their bacteriostatic activity, which allows more actively suppress the proliferation of pathogenic and opportunistic microflora, complicating the flowing of postpartum endometritis; promotes liquefaction of exudate accumulated in the uterine cavity due to enzymes included in probiotic "Bacinil"; leads to activation of local immunity of endometrial tissues due to immunostimulating activity of components of "Bacinil" and "Lactimet" probiotics; creation of low pH level in the uterine cavity due to aspartic acid and biosynthetic lactic acid. Key words: cows, postpartum endometritis, prophylaxis, acellular probiotics, aspartic acid.

A POTATO TUBERS TREATMENT INFLUENCE ON PHYTOSANITARY STATE OF POTATO PLANTINGS AND YIELD

1970 ◽  
pp. 71-73
Author(s):  
М. N. Zakharova ◽  
L. V. Rozhkova
Keyword(s):  
Sandy Loam ◽  
Humus Content ◽  
Field Tests ◽  
Low Ph ◽  
High Yield ◽  
Potato Tubers ◽  
Collective Farm ◽  
Colorado Beetle ◽  
Phosphorous Content ◽  
Ph Level

According to ISA - a branch of the FSBNU FNAC VIM in the conditions of the region from weed vegetation, pathogens of fungal, bacterial and viral diseases, a complex of soil-killing and terrestrial pests the loss of potato harvest is 30-40%. In 2019-2020 the preparations for the treatment of Gala tubers variety were tested on the V.I. Lenin collective farm in the Kasimovskiy district (Ryazan region) in accordance with the following scheme: 1. Tabu Super, VSK – 0.5 l/t + Maxim, KS – 0.4 l/t; 2. Tabu Super, VSK – 0.5 l/t + Sinclair, SC – 0.2 l/t; 3. Prestige, KS – 1.0 l/t + Regent, VDG – 0.08 kg/t + Aktara,VDG – 0.1 kg/t + Maxim, KS – 0.4 l/t. 4. Quadris, SK – 0.4 l/t + Regent, VDG – 0.08 kg/t (economic option). The area of cultivated plot is 10 hectares, the accounting area is 10 m2 and the four-time replication. The soil of the site is sod-podzolic-gley sandy loam, humus content is 0.9%, potassium – content is medium, phosphorous content is low, pH level – 5.1, the predecessor was winter wheat. As a result of field tests of fungicides and insecticides used for pre-planting treatment of potato tubers, it was found that in the region the tested drugs effectively protected the crop plants from risoctoniasis and damage to the Colorado beetle. The use of the drugs studied contributed to a high yield of potato tubers 55.5 - 60.0 tons/ha and high - above 89% output of standard tubers.

Viral Inactivation: Low pH and Detergent

2015 ◽  
Vol 69 (1) ◽  
pp. 163-172 ◽  
Author(s):  
L. Durno ◽  
O. Tounekti
Keyword(s):  
Low Ph ◽  
Viral Inactivation

Virus study for continuous low pH viral inactivation inside a coiled flow inverter

2018 ◽  
Vol 116 (4) ◽  
pp. 857-869 ◽  
Author(s):  
Laura David ◽  
Benjamin Maiser ◽  
Martin Lobedann ◽  
Peter Schwan ◽  
Michael Lasse ◽  
...  
Keyword(s):  
Low Ph ◽  
Viral Inactivation

Electroless plating of copper at a low pH level

1993 ◽  
Vol 37 (2) ◽  
pp. 117-124 ◽  
Author(s):  
R. Jagannathan ◽  
M. Krishnan
Keyword(s):  
Electroless Plating ◽  
Low Ph ◽  
Ph Level
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