scholarly journals Use of a structured kinetic model of antibody synthesis and secretion for optimization of antibody production systems: II. Transient analysis

1993 ◽  
Vol 41 (6) ◽  
pp. 683-683
Author(s):  
Theodora A. Bibila ◽  
Micheal C. Flickinger
2006 ◽  
Vol 93 (4) ◽  
pp. 779-790 ◽  
Author(s):  
Prashant M. Bapat ◽  
Sharad Bhartiya ◽  
K.V. Venkatesh ◽  
Pramod P. Wangikar

1996 ◽  
Vol 42 (2-3) ◽  
pp. 187-195 ◽  
Author(s):  
F. García-Ochoa ◽  
V.E. Santos ◽  
A. Alcón

1963 ◽  
Vol 117 (6) ◽  
pp. 1053-1062 ◽  
Author(s):  
Thomas F. O'Brien ◽  
Maria C. Michaelides ◽  
Albert H. Coons

The in vitro anamnestic antibody response of popliteal lymph node fragments to additions of antigen closely resembles the in vivo anamnestic antibody response in its sensitivity to antigen, in the time course of antibody production, and in the sequence of appearance and the morphology of the antibody containing cells. Most of the cells responsible for antibody synthesis remain in the explant and do not migrate, although a few can be found in the outgrowing sheet of cells. The smallest concentration of bovine serum albumin which stimulates an anamnestic response in vitro is about 1 x 10–9 gm/ml.


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