Kinetic study of hybridoma cell growth in continuous culture. I. A model for non-producing cells

1991 ◽  
Vol 37 (1) ◽  
pp. 55-64 ◽  
Author(s):  
Kelly K. Frame ◽  
Wei-Shou Hu
Author(s):  
A. Gfrörer ◽  
J. Spahn ◽  
W.-D. Wagner ◽  
W. Waidelich

1976 ◽  
Vol 22 (5) ◽  
pp. 611-618 ◽  
Author(s):  
P. W. Hine ◽  
H. Lees

Azotobacter chroococcum (ATCC 7493) was grown in continuous culture with intense vortex aeration (stirring rate 1750 rpm) with up to 50% O2 in the gas phase. Under these conditions the dissolved O2 generally remained at zero while the cell growth rose to about twice the normally accepted value. The meaning of the term "O2-limitation" in N2-fixing A. chroococcum cultures is critically examined.


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