A comparison of mathematical model predictions to experimental measurements for growth and recombinant protein production in induced cultures ofEscherichia coli

Michael J. Betenbaugh; Prasad Dhurjati

doi:10.1002/bit.260360204

A comparison of mathematical model predictions to experimental measurements for growth and recombinant protein production in induced cultures ofEscherichia coli

Biotechnology and Bioengineering ◽

10.1002/bit.260360204 ◽

1990 ◽

Vol 36 (2) ◽

pp. 124-134 ◽

Cited By ~ 22

Author(s):

Michael J. Betenbaugh ◽

Prasad Dhurjati

Keyword(s):

Mathematical Model ◽

Recombinant Protein ◽

Recombinant Protein Production ◽

Protein Production ◽

Ofescherichia Coli ◽

Experimental Measurements ◽

Model Predictions

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Metabolic adaptation ofEscherichia coli during temperature-induced recombinant protein production: 2. Redirection of metabolic fluxes

Biotechnology and Bioengineering ◽

10.1002/bit.10380 ◽

2002 ◽

Vol 80 (3) ◽

pp. 320-330 ◽

Cited By ~ 38

Author(s):

Jan Weber ◽

Frank Hoffmann ◽

Ursula Rinas

Keyword(s):

Recombinant Protein ◽

Recombinant Protein Production ◽

Protein Production ◽

Ofescherichia Coli ◽

Metabolic Adaptation ◽

Metabolic Fluxes

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Metabolic adaptation ofEscherichia coli during temperature-induced recombinant protein production: 1. Readjustment of metabolic enzyme synthesis

Biotechnology and Bioengineering ◽

10.1002/bit.10379 ◽

2002 ◽

Vol 80 (3) ◽

pp. 313-319 ◽

Cited By ~ 52

Author(s):

Frank Hoffmann ◽

Jan Weber ◽

Ursula Rinas

Keyword(s):

Recombinant Protein ◽

Recombinant Protein Production ◽

Protein Production ◽

Enzyme Synthesis ◽

Ofescherichia Coli ◽

Metabolic Adaptation ◽

Metabolic Enzyme

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Continuous bleed recycling significantly increases recombinant protein production yield in perfusion cell cultures

Biochemical Engineering Journal ◽

10.1016/j.bej.2021.107966 ◽

2021 ◽

Vol 169 ◽

pp. 107966

Author(s):

Jean-Marc Bielser ◽

Mathieu Aeby ◽

Stefania Caso ◽

Anaïs Roulet ◽

Hervé Broly ◽

...

Keyword(s):

Recombinant Protein ◽

Cell Cultures ◽

Recombinant Protein Production ◽

Protein Production ◽

Production Yield

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Transfection of miR-31* boosts oxidative phosphorylation metabolism in the mitochondria and enhances recombinant protein production in Chinese hamster ovary cells

Journal of Biotechnology ◽

10.1016/j.jbiotec.2021.04.012 ◽

2021 ◽

Author(s):

Jesus E. Martinez-Lopez ◽

Orla Coleman ◽

Paula Meleady ◽

Martin Clynes

Keyword(s):

Recombinant Protein ◽

Oxidative Phosphorylation ◽

Chinese Hamster Ovary ◽

Recombinant Protein Production ◽

Protein Production ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Ovary Cells

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Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells

ACS Omega ◽

10.1021/acsomega.0c06030 ◽

2021 ◽

Author(s):

Saumel Pérez-Rodriguez ◽

Tune Wulff ◽

Bjørn G. Voldborg ◽

Claudia Altamirano ◽

Mauricio A. Trujillo-Roldán ◽

...

Keyword(s):

Recombinant Protein ◽

Chinese Hamster Ovary ◽

Recombinant Protein Production ◽

Protein Production ◽

Secretory Pathway ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Proteomic Profiling ◽

Ovary Cells

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Chromatin-modifying elements for recombinant protein production in mammalian cell systems

Critical Reviews in Biotechnology ◽

10.1080/07388551.2020.1805401 ◽

2020 ◽

Vol 40 (7) ◽

pp. 1035-1043

Author(s):

Xiao Guo ◽

Chong Wang ◽

Tian-Yun Wang

Keyword(s):

Recombinant Protein ◽

Mammalian Cell ◽

Recombinant Protein Production ◽

Protein Production ◽

Cell Systems

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Construction of a binary transgenic gene expression system for recombinant protein production in the middle silk gland of the silkworm Bombyx mori

Transgenic Research ◽

10.1007/s11248-009-9328-2 ◽

2009 ◽

Vol 19 (3) ◽

pp. 473-487 ◽

Cited By ~ 56

Author(s):

Ken-ichiro Tatematsu ◽

Isao Kobayashi ◽

Keiro Uchino ◽

Hideki Sezutsu ◽

Tetsuya Iizuka ◽

...

Keyword(s):

Gene Expression ◽

Recombinant Protein ◽

Bombyx Mori ◽

Recombinant Protein Production ◽

Protein Production ◽

Expression System ◽

Silk Gland ◽

Gene Expression System ◽

Silkworm Bombyx Mori

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Improved recombinant protein production in Aspergillus oryzae lacking both α-1,3-glucan and galactosaminogalactan in batch culture with a lab-scale bioreactor

Journal of Bioscience and Bioengineering ◽

10.1016/j.jbiosc.2021.09.010 ◽

2021 ◽

Author(s):

Hikaru Ichikawa ◽

Ken Miyazawa ◽

Keisuke Komeiji ◽

Shunya Susukida ◽

Silai Zhang ◽

...

Keyword(s):

Recombinant Protein ◽

Batch Culture ◽

Aspergillus Oryzae ◽

Recombinant Protein Production ◽

Protein Production

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Investigation of CHO Secretome: Potential Way to Improve Recombinant Protein Production from Bioprocess

Journal of Bioprocessing & Biotechniques ◽

10.4172/2155-9821.1000240 ◽

2015 ◽

Vol 05 (07) ◽

Author(s):

Susmita Chaudhuri

Keyword(s):

Recombinant Protein ◽

Recombinant Protein Production ◽

Protein Production

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Engineering of the Human Cell Line HEK-293 to Enhance Recombinant Protein Production

IFAC Proceedings Volumes ◽

10.3182/20100707-3-be-2012.0110 ◽

2010 ◽

Vol 43 (6) ◽

pp. 473-478

Author(s):

Olivier Henry ◽

Yves Durocher

Keyword(s):

Recombinant Protein ◽

Cell Line ◽

Human Cell ◽

Recombinant Protein Production ◽

Protein Production ◽

Human Cell Line ◽

Hek 293

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