Peptide synthesis enzymatically catalyzed in a biphasic system: Water-water-immiscible organic solvent

1981 ◽  
Vol 23 (2) ◽  
pp. 355-360 ◽  
Author(s):  
Anatole N. Semenov ◽  
Ilya V. Berezin ◽  
Karel Martinek
Tetrahedron ◽  
1984 ◽  
Vol 40 (21) ◽  
pp. 4425-4432 ◽  
Author(s):  
Yu.L. Khmel'Nitski ◽  
Fam Khyu Dien ◽  
A.N. Semenov ◽  
Karel Martinek ◽  
B. Veruovič ◽  
...  

2021 ◽  
pp. 39-50
Author(s):  
Kuan Shiong Khoo ◽  
Kin Loong Tan ◽  
Sze Ying Lee ◽  
Pau Loke Show

2019 ◽  
Vol 37 (3) ◽  
pp. 863-870 ◽  
Author(s):  
Dandan Hou ◽  
Weiting Yu ◽  
Demeng Zhang ◽  
Lili Zhao ◽  
Xiudong Liu ◽  
...  

2007 ◽  
Vol 40 (5) ◽  
pp. 1305-1311 ◽  
Author(s):  
Yong-Ning Li ◽  
Xian-Ai Shi ◽  
Min-Hua Zong ◽  
Chun Meng ◽  
Ya-Qin Dong ◽  
...  

2018 ◽  
Vol 921 ◽  
pp. 54-59
Author(s):  
Zhi Hin Ou ◽  
Jia Hui Xu

S-licarbazepine was synthesized by asymmetric reduction of oxcarbazepine in organic solvent/phosphate buffer biphasic system with Bacillus anthracis CGMCC No.12337 as catalyst. Effects of many factors on reduction were studied. Dibutyl phthalate/phosphate buffer was selected as the optimal biphasic system for reduction. The optimum reduction conditions are as follows: volume ratio of dibutyl phthalate and phosphate buffer 1:1, 30 g/L iospropanol as co-substrate, phosphate buffer pH 5, substrate concentration 7.92 mmol/L, cell concentration 30 g/L, 32°C,180 rpm. The conversion and enantiometric excess of S-licarbazepine reached 97.32% and 99.80%. An efficient method for synthesis of S-licarbazepine was provided.


1993 ◽  
Vol 66 (5) ◽  
pp. 1566-1568 ◽  
Author(s):  
Sunil Kumar Ghosh ◽  
Usha Singh ◽  
Mohindra S. Chadha ◽  
Vasant R. Mamdapur

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