Design of cellular porous biomaterials for wall shear stress criterion

2010 ◽  
Vol 107 (4) ◽  
pp. 737-746 ◽  
Author(s):  
Yuhang Chen ◽  
Shiwei Zhou ◽  
Joseph Cadman ◽  
Qing Li
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Stress Criterion ◽  
Wall Shear ◽  
Porous Biomaterials

Design Optimization of Scaffold Microstructures Using Wall Shear Stress Criterion Towards Regulated Flow-Induced Erosion

2011 ◽  
Vol 133 (8) ◽  
Author(s):  
Yuhang Chen ◽  
Michiel Schellekens ◽  
Shiwei Zhou ◽  
Joseph Cadman ◽  
Wei Li ◽  
...  
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Design Optimization ◽  
Cellular Response ◽  
Polymer Scaffold ◽  
Erosion Process ◽  
Stress Criterion ◽  
A Cell ◽  
Wall Shear ◽  
Biomechanical Features

Tissue scaffolds aim to provide a cell-friendly biomechanical environment for facilitating cell growth. Existing studies have shown significant demands for generating a certain level of wall shear stress (WSS) on scaffold microstructural surfaces for promoting cellular response and attachment efficacy. Recently, its role in shear-induced erosion of polymer scaffold has also drawn increasing attention. This paper proposes a bi-directional evolutionary structural optimization (BESO) approach for design of scaffold microstructure in terms of the WSS uniformity criterion, by downgrading highly-stressed solid elements into fluidic elements and/or upgrading lowly-stressed fluidic elements into solid elements. In addition to this, a computational model is presented to simulate shear-induced erosion process. The effective stiffness and permeability of initial and optimized scaffold microstructures are characterized by the finite element based homogenization technique to quantify the variations of mechanical properties of scaffold during erosion. The illustrative examples show that a uniform WSS is achieved within the optimized scaffold microstructures, and their architectural and biomechanical features are maintained for a longer lifetime during shear-induced erosion process. This study provides a mathematical means to the design optimization of cellular biomaterials in terms of the WSS criterion towards controllable shear-induced erosion.

Correction: Development of a Two-Dimensional Wall Shear Stress Sensor for Wind Tunnel Applications

2019 ◽  
Author(s):  
Brett Freidkes ◽  
David A. Mills ◽  
Casey Keane ◽  
Lawrence S. Ukeiley ◽  
Mark Sheplak
Keyword(s):  
Shear Stress ◽  
Wind Tunnel ◽  
Wall Shear Stress ◽  
Two Dimensional ◽  
Stress Sensor ◽  
Shear Stress Sensor ◽  
Wall Shear

Basic study on estimation method of wall shear stress in common carotid artery using blood flow imaging

2020 ◽  
Vol 59 (SK) ◽  
pp. SKKE16 ◽  
Author(s):  
Ryo Nagaoka ◽  
Kazuma Ishikawa ◽  
Michiya Mozumi ◽  
Magnus Cinthio ◽  
Hideyuki Hasegawa
Keyword(s):  
Blood Flow ◽  
Shear Stress ◽  
Carotid Artery ◽  
Wall Shear Stress ◽  
Common Carotid Artery ◽  
Estimation Method ◽  
Flow Imaging ◽  
Basic Study ◽  
Blood Flow Imaging ◽  
Wall Shear

scholarly journals The Effect of Wall Shear Stress on Two Phase Fluctuating Flow of Dusty Fluids by Using Light Hill Technique

Water ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1587
Author(s):  
Dolat Khan ◽  
Ata ur Rahman ◽  
Gohar Ali ◽  
Poom Kumam ◽  
Attapol Kaewkhao ◽  
...  
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Base Fluid ◽  
Perturbation Technique ◽  
Fluid Velocity ◽  
Dust Particles ◽  
Stress Effect ◽  
Parallel Plates ◽  
Dusty Fluid ◽  
Wall Shear

Due to the importance of wall shear stress effect and dust fluid in daily life fluid problems. This paper aims to discover the influence of wall shear stress on dust fluids of fluctuating flow. The flow is considered between two parallel plates that are non-conducting. Due to the transformation of heat, the fluid flow is generated. We consider every dust particle having spherical uniformly disperse in the base fluid. The perturb solution is obtained by applying the Poincare-Lighthill perturbation technique (PLPT). The fluid velocity and shear stress are discussed for the different parameters like Grashof number, magnetic parameter, radiation parameter, and dusty fluid parameter. Graphical results for fluid and dust particles are plotted through Mathcad-15. The behavior of base fluid and dusty fluid is matching for different embedded parameters.

scholarly journals Numerical modeling in arterial hemodynamics incorporating fluid-structure interaction and microcirculation

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Fan He ◽  
Lu Hua ◽  
Tingting Guo
Keyword(s):  
Numerical Modeling ◽  
Shear Stress ◽  
Wall Shear Stress ◽  
Fluid Structure Interaction ◽  
Rigid Wall ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Arterial Hemodynamics ◽  
Wall Compliance ◽  
Wall Shear

Abstract Background The effects of arterial wall compliance on blood flow have been revealed using fluid-structure interaction in last decades. However, microcirculation is not considered in previous researches. In fact, microcirculation plays a key role in regulating blood flow. Therefore, it is very necessary to involve microcirculation in arterial hemodynamics. Objective The main purpose of the present study is to investigate how wall compliance affects the flow characteristics and to establish the comparisons of these flow variables with rigid wall when microcirculation is considered. Methods We present numerical modeling in arterial hemodynamics incorporating fluid-structure interaction and microcirculation. A novel outlet boundary condition is employed to prescribe microcirculation in an idealised model. Results The novel finding in this work is that wall compliance under the consideration of microcirculation leads to the increase of wall shear stress in contrast to rigid wall, contrary to the traditional result that wall compliance makes wall shear stress decrease when a constant or time dependent pressure is specified at an outlet. Conclusions This work provides the valuable study of hemodynamics under physiological and realistic boundary conditions and proves that wall compliance may have a positive impact on wall shear stress based on this model. This methodology in this paper could be used in real model simulations.

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