Identification of cell culture conditions to controlN-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells

2009 ◽  
Vol 103 (6) ◽  
pp. 1164-1175 ◽  
Author(s):  
Martin Gawlitzek ◽  
Michael Estacio ◽  
Tobias Fürch ◽  
Robert Kiss
2021 ◽  
pp. 22-26
Author(s):  
Vera Vyacheslavovna Eliseeva ◽  
Aleksandr Alekseevich Smirnov ◽  
Denis Alekseevich Mazalyov ◽  
Viktor Andreevich Kuvshinov

Chinese hamster ovary (CHO) cells cultured in bioreactors to produce various recombinant proteins for therapeutic applications. The concentration of carbon dioxide dissolved in the medium is one of the key components affecting the growth and productivity of CHO cells. Researching the effect of different concentrations рCO₂ on cells is necessary for optimization of cell culture conditions and increasing protein production. The review deals with research in this field.


2021 ◽  
Vol 1885 (3) ◽  
pp. 032004
Author(s):  
Qichao Pan ◽  
Zuwei Zhang ◽  
Yaqiong Zhang ◽  
Yaopeng Zhang ◽  
Bo Zhu

1989 ◽  
Vol 25 (9) ◽  
pp. 806-812 ◽  
Author(s):  
Tarek Bisat ◽  
Terry R. Brown ◽  
Claude J. Migeon ◽  
Gary D. Berkovitz

2011 ◽  
Vol 104 (6) ◽  
pp. 968-970 ◽  
Author(s):  
S Piaskowski ◽  
M Bienkowski ◽  
E Stoczynska-Fidelus ◽  
R Stawski ◽  
M Sieruta ◽  
...  

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