Increased recombinant protein production inEscherichia coli strains with overexpressed water-forming NADH oxidase and a deleted ArcA regulatory protein

G.N. Vemuri; M.A. Eiteman; E. Altman

doi:10.1002/bit.20853

Increased recombinant protein production inEscherichia coli strains with overexpressed water-forming NADH oxidase and a deleted ArcA regulatory protein

Biotechnology and Bioengineering ◽

10.1002/bit.20853 ◽

2006 ◽

Vol 94 (3) ◽

pp. 538-542 ◽

Cited By ~ 48

Author(s):

G.N. Vemuri ◽

M.A. Eiteman ◽

E. Altman

Keyword(s):

Recombinant Protein ◽

Recombinant Protein Production ◽

Protein Production ◽

Nadh Oxidase ◽

Regulatory Protein ◽

Inescherichia Coli

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Strain engineering to prevent norleucine incorporation during recombinant protein production inEscherichia coli

Biotechnology Progress ◽

10.1002/btpr.1999 ◽

2014 ◽

Vol 31 (1) ◽

pp. 204-211 ◽

Cited By ~ 9

Author(s):

Karthik Veeravalli ◽

Michael W. Laird ◽

Mark Fedesco ◽

Yu Zhang ◽

X. Christopher Yu

Keyword(s):

Recombinant Protein ◽

Recombinant Protein Production ◽

Protein Production ◽

Strain Engineering ◽

Inescherichia Coli

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Effect of modified glucose uptake using genetic engineering techniques on high-level recombinant protein production inescherichia coli dense cultures

Biotechnology and Bioengineering ◽

10.1002/bit.260440811 ◽

1994 ◽

Vol 44 (8) ◽

pp. 952-960 ◽

Cited By ~ 66

Author(s):

Chih-Hsiung Chou ◽

George N. Bennett ◽

Ka-Yiu San

Keyword(s):

Genetic Engineering ◽

Recombinant Protein ◽

Glucose Uptake ◽

Recombinant Protein Production ◽

Protein Production ◽

Inescherichia Coli ◽

High Level

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Metabolic load of recombinant protein production: Inhibition of cellular capacities for glucose uptake and respiration after induction of a heterologous gene inEscherichia coli

Biotechnology and Bioengineering ◽

10.1002/bit.10645 ◽

2003 ◽

Vol 83 (1) ◽

pp. 53-64 ◽

Cited By ~ 78

Author(s):

P. Neubauer ◽

H. Y. Lin ◽

B. Mathiszik

Keyword(s):

Recombinant Protein ◽

Glucose Uptake ◽

Recombinant Protein Production ◽

Protein Production ◽

Heterologous Gene ◽

Inescherichia Coli ◽

Metabolic Load

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Elevated Fis expression enhances recombinant protein production inEscherichia coli

Biotechnology and Bioengineering ◽

10.1002/(sici)1097-0290(19971020)56:2<138::aid-bit3>3.0.co;2-q ◽

1997 ◽

Vol 56 (2) ◽

pp. 138-144 ◽

Cited By ~ 4

Author(s):

Richard Richins ◽

Tin Htay ◽

Pauli Kallio ◽

Wilfred Chen

Keyword(s):

Recombinant Protein ◽

Recombinant Protein Production ◽

Protein Production ◽

Inescherichia Coli

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Process simulation for recombinant protein production: Cost estimation and sensitivity analysis for heparinase I expressed inEscherichia coli

Biotechnology and Bioengineering ◽

10.1002/(sici)1097-0290(19970320)53:6<575::aid-bit5>3.0.co;2-j ◽

1997 ◽

Vol 53 (6) ◽

pp. 575-582 ◽

Cited By ~ 26

Author(s):

Steffen Ernst ◽

Oscar A. Garro ◽

Stefan Winkler ◽

Ganesh Venkataraman ◽

Robert Langer ◽

...

Keyword(s):

Sensitivity Analysis ◽

Recombinant Protein ◽

Process Simulation ◽

Cost Estimation ◽

Recombinant Protein Production ◽

Production Cost ◽

Protein Production ◽

Inescherichia Coli ◽

Heparinase I

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Toward an era of utilizing methionine overproducing hosts for recombinant protein production inEscherichia coli

Bioengineered ◽

10.1080/21655979.2015.1030544 ◽

2015 ◽

Vol 6 (3) ◽

pp. 132-135 ◽

Cited By ~ 2

Author(s):

Karthik Veeravalli ◽

Michael W Laird

Keyword(s):

Recombinant Protein ◽

Recombinant Protein Production ◽

Protein Production ◽

Inescherichia Coli

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Genetic manipulation of stationary-phase genes to enhance recombinant protein production inEscherichia coli

Biotechnology and Bioengineering ◽

10.1002/(sici)1097-0290(19960620)50:6<636::aid-bit4>3.0.co;2-l ◽

1996 ◽

Vol 50 (6) ◽

pp. 636-642 ◽

Cited By ~ 15

Author(s):

Chih-Hsiung Chou ◽

George N. Bennett ◽

Ka-Yiu San

Keyword(s):

Recombinant Protein ◽

Stationary Phase ◽

Recombinant Protein Production ◽

Protein Production ◽

Genetic Manipulation ◽

Inescherichia Coli

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Continuous bleed recycling significantly increases recombinant protein production yield in perfusion cell cultures

Biochemical Engineering Journal ◽

10.1016/j.bej.2021.107966 ◽

2021 ◽

Vol 169 ◽

pp. 107966

Author(s):

Jean-Marc Bielser ◽

Mathieu Aeby ◽

Stefania Caso ◽

Anaïs Roulet ◽

Hervé Broly ◽

...

Keyword(s):

Recombinant Protein ◽

Cell Cultures ◽

Recombinant Protein Production ◽

Protein Production ◽

Production Yield

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Transfection of miR-31* boosts oxidative phosphorylation metabolism in the mitochondria and enhances recombinant protein production in Chinese hamster ovary cells

Journal of Biotechnology ◽

10.1016/j.jbiotec.2021.04.012 ◽

2021 ◽

Author(s):

Jesus E. Martinez-Lopez ◽

Orla Coleman ◽

Paula Meleady ◽

Martin Clynes

Keyword(s):

Recombinant Protein ◽

Oxidative Phosphorylation ◽

Chinese Hamster Ovary ◽

Recombinant Protein Production ◽

Protein Production ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Ovary Cells

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Compartmentalized Proteomic Profiling Outlines the Crucial Role of the Classical Secretory Pathway during Recombinant Protein Production in Chinese Hamster Ovary Cells

ACS Omega ◽

10.1021/acsomega.0c06030 ◽

2021 ◽

Author(s):

Saumel Pérez-Rodriguez ◽

Tune Wulff ◽

Bjørn G. Voldborg ◽

Claudia Altamirano ◽

Mauricio A. Trujillo-Roldán ◽

...

Keyword(s):

Recombinant Protein ◽

Chinese Hamster Ovary ◽

Recombinant Protein Production ◽

Protein Production ◽

Secretory Pathway ◽

Chinese Hamster Ovary Cells ◽

Chinese Hamster ◽

Proteomic Profiling ◽

Ovary Cells

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