Optimized procedure for renaturation of recombinant human bone morphogenetic protein-2 at high protein concentration

Luis Felipe Vallejo; Ursula Rinas

doi:10.1002/bit.10906

Optimized procedure for renaturation of recombinant human bone morphogenetic protein-2 at high protein concentration

Biotechnology and Bioengineering ◽

10.1002/bit.10906 ◽

2004 ◽

Vol 85 (6) ◽

pp. 601-609 ◽

Cited By ~ 66

Author(s):

Luis Felipe Vallejo ◽

Ursula Rinas

Keyword(s):

Bone Morphogenetic Protein ◽

Protein Concentration ◽

High Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

High Protein Concentration ◽

Human Bone Morphogenetic Protein ◽

Recombinant Human Bone

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Optimized procedure for expression and renaturation of recombinant human bone morphogenetic protein-2 at high protein concentrations

Molecular Biology Reports ◽

10.1007/s11033-009-9883-x ◽

2009 ◽

Vol 37 (7) ◽

pp. 3089-3095 ◽

Cited By ~ 13

Author(s):

Hongbin Zhang ◽

Jie Wu ◽

Yu Zhang ◽

Na Fu ◽

Jie Wang ◽

...

Keyword(s):

Bone Morphogenetic Protein ◽

High Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Recombinant Human Bone

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Faculty Opinions recommendation of Routine use of recombinant human bone morphogenetic protein-2 in posterior fusions of the pediatric spine: safety profile and efficacy in the early postoperative period.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.7129956.7361054 ◽

2010 ◽

Author(s):

Thomas Milhorat ◽

Misao Nishikawa

Keyword(s):

Bone Morphogenetic Protein ◽

Postoperative Period ◽

Safety Profile ◽

Early Postoperative Period ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Pediatric Spine ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Recombinant Human Bone

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Faculty Opinions recommendation of Safety and effectiveness of recombinant human bone morphogenetic protein-2 for spinal fusion: a meta-analysis of individual-participant data.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718026356.793479779 ◽

2013 ◽

Author(s):

Dan Gazit ◽

Gadi Pelled

Keyword(s):

Spinal Fusion ◽

Bone Morphogenetic Protein ◽

Meta Analysis ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Individual Participant Data ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Individual Participant ◽

Recombinant Human Bone

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Faculty Opinions recommendation of Short-Term Teriparatide and Recombinant Human Bone Morphogenetic Protein-2 for Regenerative Approach to Medication-Related Osteonecrosis of the Jaw: A Preliminary Study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.728769606.793542319 ◽

2018 ◽

Author(s):

Mark Johnson

Keyword(s):

Bone Morphogenetic Protein ◽

Osteonecrosis Of The Jaw ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Short Term ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Regenerative Approach ◽

Preliminary Study ◽

Recombinant Human Bone

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Bisphosphonate incadronate inhibits maturation of ectopic bone induced by recombinant human bone morphogenetic protein 2

Journal of Bone and Mineral Metabolism ◽

10.1007/s007740300001 ◽

2003 ◽

Vol 21 (1) ◽

pp. 5-11 ◽

Cited By ~ 12

Author(s):

Lin Gong ◽

Kazuto Hoshi ◽

Sadakazu Ejiri ◽

Tamio Nakajima ◽

Susumu Shingaki ◽

...

Keyword(s):

Bone Morphogenetic Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

Ectopic Bone ◽

Human Bone Morphogenetic Protein ◽

Recombinant Human Bone

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The osteogenic potential of recombinant human bone morphogenetic protein-9 compared to recombinant human bone morphogenetic protein-2 for bone regeneration

International Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.ijom.2017.02.1167 ◽

2017 ◽

Vol 46 ◽

pp. 346

Author(s):

M. Kobayashi ◽

E. Kobayashi ◽

N. Saulacic ◽

B. Schaller ◽

T. Iizuka ◽

...

Keyword(s):

Bone Regeneration ◽

Bone Morphogenetic Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Osteogenic Potential ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Bone Morphogenetic Protein 9 ◽

Recombinant Human Bone

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Recombinant Human Bone Morphogenetic Protein-2 Promotes Wound Healing in Rat Periodontal Fenestration Defects

Journal of Dental Research ◽

10.1177/00220345970760080801 ◽

1997 ◽

Vol 76 (8) ◽

pp. 1460-1470 ◽

Cited By ~ 163

Author(s):

G.N. King ◽

N. King ◽

A.T. Cruchley ◽

J.M. Wozney ◽

F.J. Hughes

Keyword(s):

Wound Healing ◽

Bone Morphogenetic Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Recombinant Human Bone

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Preparation and Biological Characteristics of Recombinant Human Bone Morphogenetic Protein-2-Loaded Dextran-co-Gelatin Hydrogel Microspheres, in vitro and in vivo Studies

Pharmacology ◽

10.1159/000088212 ◽

2005 ◽

Vol 75 (3) ◽

pp. 133-144 ◽

Cited By ~ 25

Author(s):

Faming Chen ◽

Zhifen Wu ◽

Qintao Wang ◽

Hong Wu ◽

Yongjie Zhang ◽

...

Keyword(s):

Bone Morphogenetic Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

In Vivo Studies ◽

Gelatin Hydrogel ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Recombinant Human Bone

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Enhanced osteoinductivity of recombinant human bone morphogenetic protein-2 in combination with epidermal growth factor in a rabbit tibial defect model

Growth Factors ◽

10.3109/08977194.2014.957759 ◽

2014 ◽

Vol 33 (1) ◽

pp. 31-39 ◽

Cited By ~ 3

Author(s):

Jae Hyup Lee ◽

Hae-Ri Baek ◽

Kyung Mee Lee ◽

Dong-Yeon Lee ◽

A-Young Lee

Keyword(s):

Growth Factor ◽

Epidermal Growth Factor ◽

Bone Morphogenetic Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Defect Model ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Epidermal Growth ◽

Recombinant Human Bone

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Use of recombinant human bone morphogenetic protein-2 (rhBMP-2) as an adjunct for instrumented posterior arthrodesis in the occipital cervical region: An analysis of safety, efficacy and dosing

Journal of Craniovertebral Junction and Spine ◽

10.4103/0974-8237.100079 ◽

2011 ◽

Vol 2 (2) ◽

pp. 103 ◽

Cited By ~ 1

Author(s):

DK Hamilton ◽

JS Smith ◽

DL Reames ◽

BJ Williams ◽

CI Shaffrey

Keyword(s):

Bone Morphogenetic Protein ◽

Human Bone ◽

Bone Morphogenetic Protein 2 ◽

Cervical Region ◽

Morphogenetic Protein ◽

Human Bone Morphogenetic Protein ◽

Posterior Arthrodesis ◽

Recombinant Human Bone

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