Pyrrolidinyl peptide nucleic acids bearing hydroxy‐modified cyclobutane building blocks: Synthesis and binding properties

Biopolymers ◽  
2021 ◽  
Author(s):  
Boonsong Ditmangklo ◽  
Wantanee Sittiwong ◽  
Thomas Boddaert ◽  
Tirayut Vilaivan ◽  
David J. Aitken
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Building Blocks ◽  
Binding Properties

Synthesis of new building blocks for peptide nucleic acids containing monomers with variations in the backbone

1997 ◽  
Vol 7 (6) ◽  
pp. 681-686 ◽  
Author(s):  
Stephan Jordan ◽  
Christoph Schwemler ◽  
Winfried Kosch ◽  
Axel Kretschmer ◽  
Eckhardt Schwenner ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Building Blocks

Microwave Assisted Synthesis of N-(ethoxycarbonylmethyl)-nucleobases: Building Blocks for PNAs

2005 ◽  
Vol 2005 (3) ◽  
pp. 167-168 ◽  
Author(s):  
Gui-Rong Qu ◽  
Yong Li ◽  
Su-Hui Han
Keyword(s):  
Microwave Irradiation ◽  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Building Blocks ◽  
Microwave Assisted Synthesis ◽  
Ethyl Bromoacetate ◽  
Microwave Assisted

The synthesis of N1/N9- (Ethoxycarbonylmethyl)pyrimidine/purine using as synthons for peptide nucleic acids has been described. Microwave irradiation provided the desired products by alkylation of the appropriately protected natural and substituted nucleobases with ethyl bromoacetate within 4–7 min in 48–85% yields.

scholarly journals Protected Maleimide Building Blocks for the Decoration of Peptides, Peptoids, and Peptide Nucleic Acids

2013 ◽  
Vol 24 (5) ◽  
pp. 832-839 ◽  
Author(s):  
Xavier Elduque ◽  
Albert Sánchez ◽  
Kapil Sharma ◽  
Enrique Pedroso ◽  
Anna Grandas
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Building Blocks

Synthesis and DNA binding properties of dioxime–peptide nucleic acids

2004 ◽  
Vol 14 (11) ◽  
pp. 2927-2930 ◽  
Author(s):  
Andriy Mokhir ◽  
Roland Krämer ◽  
Yan Z. Voloshin ◽  
Oleg A. Varzatskii
Keyword(s):  
Dna Binding ◽  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Binding Properties ◽  
Dna Binding Properties

Synthesis of New Chiral Building Blocks for Novel Peptide Nucleic Acids

2010 ◽  
Vol 21 (5) ◽  
pp. 566-573
Author(s):  
Wu Jie ◽  
Xu Xiao-Yu ◽  
Liu Ke-Liang
Keyword(s):  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Building Blocks

Synthesis and RNA-Binding Properties of Extended Nucleobases for Triplex-Forming Peptide Nucleic Acids

2019 ◽  
Vol 84 (21) ◽  
pp. 13276-13298
Author(s):  
Ilze Kumpina ◽  
Nikita Brodyagin ◽  
James A. MacKay ◽  
Scott D. Kennedy ◽  
Martins Katkevics ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Rna Binding ◽  
Peptide Nucleic Acids ◽  
Binding Properties

Synthesis and DNA binding properties of terminally modified peptide nucleic acids

2003 ◽  
Vol 13 (15) ◽  
pp. 2489-2492 ◽  
Author(s):  
Andriy Mokhir ◽  
Burkhard Zohm ◽  
Andreas Fuessl ◽  
Roland Kraemer
Keyword(s):  
Dna Binding ◽  
Nucleic Acids ◽  
Peptide Nucleic Acids ◽  
Binding Properties ◽  
Dna Binding Properties
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