scholarly journals Electrostatic properties of cowpea chlorotic mottle virus and cucumber mosaic virus capsids

Biopolymers ◽  
2006 ◽  
Vol 82 (2) ◽  
pp. 106-120 ◽  
Author(s):  
Robert Konecny ◽  
Joanna Trylska ◽  
Florence Tama ◽  
Deqiang Zhang ◽  
Nathan A. Baker ◽  
...  
Keyword(s):  
Cucumber Mosaic Virus ◽  
Mosaic Virus ◽  
Mottle Virus ◽  
Cowpea Chlorotic Mottle Virus ◽  
Electrostatic Properties ◽  
Chlorotic Mottle Virus ◽  
Chlorotic Mottle ◽  
Virus Capsids

scholarly journals The Structure of Cucumber Mosaic Virus and Comparison to Cowpea Chlorotic Mottle Virus

2000 ◽  
Vol 74 (16) ◽  
pp. 7578-7586 ◽  
Author(s):  
Thomas J. Smith ◽  
Elaine Chase ◽  
Timothy Schmidt ◽  
Keith L. Perry
Keyword(s):  
Cucumber Mosaic Virus ◽  
Mosaic Virus ◽  
Aphid Transmission ◽  
Mottle Virus ◽  
Dependent Manner ◽  
Threefold Axis ◽  
Cowpea Chlorotic Mottle Virus ◽  
X Ray Crystallography ◽  
Chlorotic Mottle Virus ◽  
Chlorotic Mottle

ABSTRACT The structure of cucumber mosaic virus (CMV; strain Fny) has been determined to a 3.2-Å resolution using X-ray crystallography. Despite the fact that CMV has only 19% capsid protein sequence identity (34% similarity) to cowpea chlorotic mottle virus (CCMV), the core structures of these two members of the Bromoviridaefamily are highly homologous. As suggested by a previous low-resolution structural study, the 305-Å diameter (maximum) of CMV is ∼12 Å larger than that of CCMV. In CCMV, the structures of the A, B, and C subunits are nearly identical except in their N termini. In contrast, the structures of two loops in subunit A of CMV differ from those in B and C. These loops are 6 and 7 residues longer than the analogous regions in CCMV. Unlike that of CCMV, the capsid of CMV does not undergo swelling at pH 7.0 and is stable at pH 9.0. This may be partly due to the fact that the N termini of the B and C subunits form a unique bundle of six amphipathic helices oriented down into the virion core at the threefold axes. In addition, while CCMV has a cluster of aspartic acid residues at the quasi-threefold axis that are proposed to bind metal in a pH-dependent manner, this cluster is replaced by complementing acids and bases in CMV. Finally, this structure clearly demonstrates that the residues important for aphid transmission lie at the outermost portion of the βH-βI loop and yields details of the portions of the virus that are hypothesized to mediate binding to aphid mouthparts.

scholarly journals Synergistic Effects of Mutations and Nanoparticle Templating in the Self-Assembly of Cowpea Chlorotic Mottle Virus Capsids

Nano Letters ◽  
2009 ◽  
Vol 9 (1) ◽  
pp. 393-398 ◽  
Author(s):  
Stella E. Aniagyei ◽  
Chelsea J. Kennedy ◽  
Barry Stein ◽  
Deborah A. Willits ◽  
Trevor Douglas ◽  
...  
Keyword(s):  
Self Assembly ◽  
Synergistic Effects ◽  
The Self ◽  
Mottle Virus ◽  
Cowpea Chlorotic Mottle Virus ◽  
Chlorotic Mottle Virus ◽  
Chlorotic Mottle ◽  
Virus Capsids
Sign in / Sign up

Export Citation Format

Share Document