Statistical mechanics of protein folding with separable energy functions

Biopolymers ◽  
2004 ◽  
Vol 74 (3) ◽  
pp. 214-220 ◽  
Author(s):  
Jianyong Wang ◽  
Gordon M. Crippen
2009 ◽  
Author(s):  
Alexander Yakubovich ◽  
Andrey V. Solov’yov ◽  
Walter Greiner ◽  
Andrey Solov́yov ◽  
Eugene Surdutovich

1997 ◽  
Vol 73 (6) ◽  
pp. 3192-3210 ◽  
Author(s):  
V.S. Pande ◽  
A.Y. Grosberg ◽  
T. Tanaka

Author(s):  
Peter G. Wolynes

Energy–landscape theory has led to much progress in protein folding kinetics, protein structure prediction and protein design. Funnel landscapes describe protein folding and binding and explain how protein topology determines kinetics. Landscape–optimized energy functions based on bioinformatic input have been used to correctly predict low–resolution protein structures and also to design novel proteins automatically.


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