scholarly journals Multi‐Omics Reveals Impact of Cysteine Feed Concentration and Resulting Redox Imbalance on Cellular Energy Metabolism and Specific Productivity in CHO Cell Bioprocessing

2020 ◽  
Vol 15 (8) ◽  
pp. 1900565
Author(s):  
Amr S. Ali ◽  
Rachel Chen ◽  
Ravali Raju ◽  
Rashmi Kshirsagar ◽  
Alan Gilbert ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Specific Productivity ◽  
Cho Cell ◽  
Feed Concentration ◽  
Redox Imbalance ◽  
Cellular Energy ◽  
Cellular Energy Metabolism

scholarly journals Glucose stimulates intestinal epithelial crypt proliferation by modulating cellular energy metabolism

2017 ◽  
Vol 233 (4) ◽  
pp. 3465-3475 ◽  
Author(s):  
Weinan Zhou ◽  
Deepti Ramachandran ◽  
Abdelhak Mansouri ◽  
Megan J. Dailey
Keyword(s):  
Energy Metabolism ◽  
Intestinal Epithelial ◽  
Cellular Energy ◽  
Cellular Energy Metabolism

scholarly journals Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis

2016 ◽  
Vol 5 (4) ◽  
pp. 283-295 ◽  
Author(s):  
Torsten Schröder ◽  
David Kucharczyk ◽  
Florian Bär ◽  
René Pagel ◽  
Stefanie Derer ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Gene Polymorphisms ◽  
Mitochondrial Gene ◽  
Cellular Energy ◽  
Cellular Energy Metabolism ◽  
Alcoholic Steatohepatitis

scholarly journals The dynamics of mitochondrial-linked gene expression among tissues and life stages in two contrasting strains of laying hens

PLoS ONE ◽  
2022 ◽  
Vol 17 (1) ◽  
pp. e0262613
Author(s):  
Clara Dreyling ◽  
Martin Hasselmann
Keyword(s):  
Gene Expression ◽  
Energy Metabolism ◽  
Life Span ◽  
Laying Hens ◽  
Mitochondrial Gene ◽  
Model Organisms ◽  
Life Stages ◽  
Mitochondrial Gene Expression ◽  
Cellular Energy ◽  
Cellular Energy Metabolism

The cellular energy metabolism is one of the most conserved processes, as it is present in all living organisms. Mitochondria are providing the eukaryotic cell with energy and thus their genome and gene expression has been of broad interest for a long time. Mitochondrial gene expression changes under different conditions and is regulated by genes encoded in the nucleus of the cell. In this context, little is known about non-model organisms and we provide the first large-scaled gene expression analysis of mitochondrial-linked genes in laying hens. We analysed 28 mitochondrial and nuclear genes in 100 individuals in the context of five life-stages and strain differences among five tissues. Our study showed that mitochondrial gene expression increases during the productive life span, and reacts tissue and strain specific. In addition, the strains react different to potential increased oxidative stress, resulting from the increase in mitochondrial gene expression. The results suggest that the cellular energy metabolism as part of a complex regulatory system is strongly affected by the productive life span in laying hens and thus partly comparable to model organisms. This study provides a starting point for further analyses in this field on non-model organisms, especially in laying-hens.

scholarly journals Simultaneous Multiparameter Cellular Energy Metabolism Profiling of Small Populations of Cells

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Laimonas Kelbauskas ◽  
Shashaanka P. Ashili ◽  
Kristen B. Lee ◽  
Haixin Zhu ◽  
Yanqing Tian ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Small Populations ◽  
Cellular Energy ◽  
Cellular Energy Metabolism

scholarly journals Atoms to Phenotypes: Molecular Design Principles of Cellular Energy Metabolism

Cell ◽  
2019 ◽  
Vol 179 (5) ◽  
pp. 1098-1111.e23 ◽  
Author(s):  
Abhishek Singharoy ◽  
Christopher Maffeo ◽  
Karelia H. Delgado-Magnero ◽  
David J.K. Swainsbury ◽  
Melih Sener ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Molecular Design ◽  
Design Principles ◽  
Cellular Energy ◽  
Cellular Energy Metabolism
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