scholarly journals Affinity Chromatography: An Enabling Technology for Large‐Scale Bioprocessing

2019 ◽  
Vol 15 (1) ◽  
pp. 1800397 ◽  
Author(s):  
Karol M. Łącki ◽  
Frank J. Riske
2021 ◽  
Vol 2 (7) ◽  
pp. 01-02
Author(s):  
Frank Riske ◽  
Brendan Riske

Affinity chromatography was initially used to describe chromatographic biological interactions such as lectin-glycoprotein, antibody -antigen and enzyme-inhibitor. This definition has expanded to include the specific interaction between a target and a ligand. The use of affinity chromatography has reached a zenith with the explosion of Mab therapeutics and the use of Protein-A chromatography for antibody capture. Now, affinity chromatography has moved to non Mab proteins. This can result in the same economic advantages as Mab, by enabling the standardization of process development and manufacturing processes in flexible multiproduct production sites. The output is improved product throughput, higher target recoveries, and potentially less expensive drugs. These advantages are available to the developed world but how do we make this technology available to the developing world?


SPIE Newsroom ◽  
2011 ◽  
Author(s):  
Hercules Avramopoulos ◽  
Maria Spyropoulou ◽  
Graeme Maxwell ◽  
Karl-Otto Velthaus ◽  
Katarina Boustedt ◽  
...  

1987 ◽  
Vol 5 (12) ◽  
pp. 1290-1293 ◽  
Author(s):  
Yannis D. Clonis

Membranes ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 25 ◽  
Author(s):  
Thijs Peters ◽  
Alessio Caravella

Palladium (Pd)-based membranes have received a lot of attention from both academia and industry thanks to their ability to selectively separate hydrogen from gas streams. Integration of such membranes with appropriate catalysts in membrane reactors allows for hydrogen production with CO2 capture that can be applied in smaller bioenergy or combined heat and power (CHP) plants, as well as in large-scale power plants. Pd-based membranes are, therefore, regarded as a Key Enabling Technology (KET) to facilitate the transition towards a knowledge-based, low carbon and resource-efficient economy. This Special Issue of the journal Membranes on “Pd-based Membranes: Overview and Perspectives” contains nine peer-reviewed articles. Topics include manufacturing techniques, understanding of material phenomena, module and reactor design, novel applications, and demonstration efforts and industrial exploitation.


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