Asymmetric synthesis of aromatic β-amino acids using ω-transaminase: Optimizing the lipase concentration to obtain thermodynamically unstable β-keto acids

Sam Mathew; Seong-Su Jeong; Taeowan Chung; Sang-Hyeup Lee; Hyungdon Yun

doi:10.1002/biot.201500181

Asymmetric synthesis of aromatic β-amino acids using ω-transaminase: Optimizing the lipase concentration to obtain thermodynamically unstable β-keto acids

Biotechnology Journal ◽

10.1002/biot.201500181 ◽

2015 ◽

Vol 11 (1) ◽

pp. 185-190 ◽

Cited By ~ 23

Author(s):

Sam Mathew ◽

Seong-Su Jeong ◽

Taeowan Chung ◽

Sang-Hyeup Lee ◽

Hyungdon Yun

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Keto Acids

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ChemInform Abstract: STEREOSELECTIVITY IN REACTIONS OF METAL COMPLEXES. VIII. ASYMMETRIC SYNTHESIS S OF SOME AMINO ACIDS BY STEREOSELECTIVE TRANSAMINATION OF ALIPHATIC KETO ACIDS IN MIXED LIGAND COPPER(II)-SCHIFF-BASE COMPLEXES

Chemischer Informationsdienst ◽

10.1002/chin.198422296 ◽

1984 ◽

Vol 15 (22) ◽

Author(s):

R. DESCHENAUX ◽

K. BERNAUER

Keyword(s):

Amino Acids ◽

Schiff Base ◽

Metal Complexes ◽

Asymmetric Synthesis ◽

Mixed Ligand ◽

Schiff Base Complexes ◽

Keto Acids

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ChemInform Abstract: EFFICIENT ASYMMETRIC SYNTHESIS OF α-AMINO ACIDS FROM α-KETO ACIDS AND AMMONIA WITH CONSERVATION OF THE CHIRAL REAGENT

Chemischer Informationsdienst ◽

10.1002/chin.197615157 ◽

1976 ◽

Vol 7 (15) ◽

pp. no-no

Author(s):

B. W. BYCROFT ◽

G. R. LEE

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Chiral Reagent ◽

Keto Acids

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Biocatalytic Asymmetric Synthesis of Unnatural Amino Acids through the Cascade Transfer of Amino Groups from Primary Amines onto Keto Acids

ChemCatChem ◽

10.1002/cctc.201300571 ◽

2013 ◽

Vol 5 (12) ◽

pp. 3538-3542 ◽

Cited By ~ 24

Author(s):

Eul-Soo Park ◽

Joo-Young Dong ◽

Jong-Shik Shin

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Unnatural Amino Acids ◽

Primary Amines ◽

Amino Groups ◽

Keto Acids

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Stereoselectivity in reactions of metal complexes VIII. Asymmetric synthesis of some amino acids by stereoselective transamination of aliphatic keto acids in mixed ligand copper(II)-Schiff-base complexes

Helvetica Chimica Acta ◽

10.1002/hlca.19840670203 ◽

1984 ◽

Vol 67 (2) ◽

pp. 373-377 ◽

Cited By ~ 29

Author(s):

Robert Deschenaux ◽

Klaus Bernauer

Keyword(s):

Amino Acids ◽

Schiff Base ◽

Metal Complexes ◽

Asymmetric Synthesis ◽

Mixed Ligand ◽

Schiff Base Complexes ◽

Keto Acids

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ChemInform Abstract: Biocatalytic Asymmetric Synthesis of Unnatural Amino Acids Through the Cascade Transfer of Amino Groups from Primary Amines onto Keto Acids.

ChemInform ◽

10.1002/chin.201416036 ◽

2014 ◽

Vol 45 (16) ◽

pp. no-no

Author(s):

Eul-Soo Park ◽

Joo-Young Dong ◽

Jong-Shik Shin

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Unnatural Amino Acids ◽

Primary Amines ◽

Amino Groups ◽

Keto Acids

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Efficient asymmetric synthesis of α-amino acids from α-keto acids and ammonia with conservation of the chiral reagent

Journal of the Chemical Society Chemical Communications ◽

10.1039/c39750000988 ◽

1975 ◽

pp. 988-989 ◽

Cited By ~ 34

Author(s):

Barrie W. Bycroft ◽

Grahame R. Lee

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Chiral Reagent ◽

Keto Acids

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Total asymmetric synthesis of highly constrained amino acids β-isopropyl-2′,6′-dimethyl-tyrosines

Tetrahedron Letters ◽

10.1016/s0040-4039(97)01094-0 ◽

1997 ◽

Vol 38 (29) ◽

pp. 5135-5138 ◽

Cited By ~ 11

Author(s):

Yinglin Han ◽

Subo Liao ◽

Wei Qiu ◽

Chaozhong Cai ◽

Victor J. Hruby

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Constrained Amino Acids

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ChemInform Abstract: Asymmetric Synthesis of Unusual Amino Acids: Synthesis of the Optically Pure Isomers of Indole-Protected β-Methyltryptophan Suitable for Peptide Synthesis.

ChemInform ◽

10.1002/chin.199317235 ◽

2010 ◽

Vol 24 (17) ◽

pp. no-no

Author(s):

L. W. BOTEJU ◽

K. WEGNER ◽

V. J. HRUBY

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Peptide Synthesis ◽

Unusual Amino Acids ◽

Optically Pure

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Interaction of branched chain amino acids and keto acids upon pancreatic islet metabolism and insulin secretion.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(20)79709-7 ◽

1980 ◽

Vol 255 (15) ◽

pp. 7340-7346

Author(s):

J.C. Hutton ◽

A. Sener ◽

W.J. Malaisse

Keyword(s):

Amino Acids ◽

Insulin Secretion ◽

Pancreatic Islet ◽

Branched Chain Amino Acids ◽

Keto Acids ◽

Islet Metabolism ◽

Branched Chain

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Development of a Recyclable Fluorous Chiral Phase-Transfer Catalyst: Application to the Catalytic Asymmetric Synthesis of α-Amino Acids.

ChemInform ◽

10.1002/chin.200435186 ◽

2004 ◽

Vol 35 (35) ◽

Author(s):

Seiji Shirakawa ◽

Youhei Tanaka ◽

Keiji Maruoka

Keyword(s):

Amino Acids ◽

Asymmetric Synthesis ◽

Phase Transfer ◽

Phase Transfer Catalyst ◽

Chiral Phase ◽

Catalytic Asymmetric Synthesis ◽

Catalytic Asymmetric

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