Concord grape juice supplementation reduces blood pressure in Korean hypertensive men: Double-blind, placebo controlled intervention trial

BioFactors ◽  
2004 ◽  
Vol 22 (1-4) ◽  
pp. 145-147 ◽  
Author(s):  
Yoo Kyoung Park ◽  
Jung-Shin Kim ◽  
Myung-Hee Kang
Keyword(s):  
Blood Pressure ◽  
Grape Juice ◽  
Intervention Trial ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Concord Grape

scholarly journals Correction to: A single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double-blind, placebo study

2020 ◽  
Author(s):  
Lydiane de Lima Tavares Toscano ◽  
Alexandre Sérgio Silva ◽  
Ana Carla Lima de França ◽  
Bruno Rafael Virgínio de Sousa ◽  
Eder Jackson Bezerra de Almeida Filho ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Single Dose ◽  
Physical Performance ◽  
Grape Juice ◽  
Double Blind ◽  
Double Blind Placebo

The article A single dose of purple grape juice improves physical performance and antioxidant activity in runners.

Effect of a low dose of midazolam on high blood pressure in dental patients: a randomised, double-blind, placebo-controlled, two-centre study

2016 ◽  
Vol 54 (4) ◽  
pp. 443-448 ◽  
Author(s):  
Yoshihisa Watanabe ◽  
Hitoshi Higuchi ◽  
Minako Ishii-Maruhama ◽  
Yuka Honda ◽  
Akiko Yabuki-Kawase ◽  
...  
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Low Dose ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Centre Study ◽  
Dental Patients

scholarly journals Oral nitrate supplementation to enhance pulmonary rehabilitation in COPD: ON-EPIC a multicentre, double-blind, placebo-controlled, randomised parallel group study

Thorax ◽  
2020 ◽  
Vol 75 (7) ◽  
pp. 547-555
Author(s):  
Matthew J Pavitt ◽  
Rebecca Jayne Tanner ◽  
Adam Lewis ◽  
Sara Buttery ◽  
Bhavin Mehta ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Active Treatment ◽  
Treatment Effect ◽  
Pulmonary Rehabilitation ◽  
Activity Level ◽  
Double Blind ◽  
Dietary Nitrate ◽  
Double Blind Placebo ◽  
Parallel Group ◽  
Nitrate Supplementation

RationaleDietary nitrate supplementation has been proposed as a strategy to improve exercise performance, both in healthy individuals and in people with COPD. We aimed to assess whether it could enhance the effect of pulmonary rehabilitation (PR) in COPD.MethodsThis double-blind, placebo-controlled, parallel group, randomised controlled study performed at four UK centres, enrolled adults with Global Initiative for Chronic Obstructive Lung Disease grade II–IV COPD and Medical Research Council dyspnoea score 3–5 or functional limitation to undertake a twice weekly 8-week PR programme. They were randomly assigned (1:1) to either 140 mL of nitrate-rich beetroot juice (BRJ) (12.9 mmol nitrate), or placebo nitrate-deplete BRJ, consumed 3 hours prior to undertaking each PR session. Allocation used computer-generated block randomisation.MeasurementsThe primary outcome was change in incremental shuttle walk test (ISWT) distance. Secondary outcomes included quality of life, physical activity level, endothelial function via flow-mediated dilatation, fat-free mass index and blood pressure parameters.Results165 participants were recruited, 78 randomised to nitrate-rich BRJ and 87 randomised to placebo. Exercise capacity increased more with active treatment (n=57) than placebo (n=65); median (IQR) change in ISWT distance +60 m (10, 85) vs +30 m (0, 70), estimated treatment effect 30 m (95% CI 10 to 40); p=0.027. Active treatment also impacted on systolic blood pressure: treatment group −5.0 mm Hg (−5.0, –3.0) versus control +6.0 mm Hg (−1.0, 15.5), estimated treatment effect −7 mm Hg (95% CI 7 to −20) (p<0.0005). No significant serious adverse events or side effects were reported.ConclusionsDietary nitrate supplementation appears to be a well-tolerated and effective strategy to augment the benefits of PR in COPD.Trial registration numberISRCTN27860457.

scholarly journals Blueberries Improve Endothelial Function, but Not Blood Pressure, in Adults with Metabolic Syndrome: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Nutrients ◽  
2015 ◽  
Vol 7 (6) ◽  
pp. 4107-4123 ◽  
Author(s):  
April Stull ◽  
Katherine Cash ◽  
Catherine Champagne ◽  
Alok Gupta ◽  
Raymond Boston ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Clinical Trial ◽  
Endothelial Function ◽  
Controlled Clinical Trial ◽  
Double Blind ◽  
Double Blind Placebo
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