scholarly journals Joint modeling of interval counts of recurrent events and death

2020 ◽  
Author(s):  
Marie Böhnstedt ◽  
Hein Putter ◽  
Aleksandra Dańko ◽  
Maciej J. Dańko ◽  
Jutta Gampe
Biostatistics ◽  
2018 ◽  
Author(s):  
Giorgio Paulon ◽  
Maria De Iorio ◽  
Alessandra Guglielmi ◽  
Francesca Ieva

Biometrics ◽  
2017 ◽  
Vol 73 (4) ◽  
pp. 1150-1160 ◽  
Author(s):  
Qing Cai ◽  
Mei‐Cheng Wang ◽  
Kwun Chuen Gary Chan

2020 ◽  
pp. 004912412091492
Author(s):  
Grace Li ◽  
Mary Lesperance ◽  
Zheng Wu

The Cox proportional hazards model has been pervasively used in many social science areas to examine the effects of covariates on timing to an event. The standard Cox model is intended to study univariate survival data where there is a singular event of interest, which can only be experienced once. However, we may additionally wish to explore a number of other complexities that are prevalent in survival data. For example, an individual may experience events of the same type more than once or may experience multiple types of events. This study introduces innovations in recurrent (repeatable) event analysis, jointly modeling several endogenous survival processes. As an example and an application, we simultaneously model two types of recurrent events in the presence of a dependent terminal event. This model not only correctly handles different types of recurrent events but also explicitly estimates the direction and magnitude of relationships between recurrences and survival. This article concludes with an example of the model to examine how the timing of retirement is associated with the risks of multiple spells of employment and childbearing. The theoretical discussions and empirical analyses suggest that the multivariate joint models have much to offer to a wide variety of substantive research areas.


2020 ◽  
Vol 91 (4) ◽  
pp. 352-357
Author(s):  
Jessica Tedford ◽  
Valerie Skaggs ◽  
Ann Norris ◽  
Farhad Sahiar ◽  
Charles Mathers

INTRODUCTION: Atrial fibrillation (AF) is one of the most common cardiac arrhythmias in the general population and is considered disqualifying aeromedically. This study is a unique examination of significant outcomes in aviators with previous history of both AF and stroke.METHODS: Pilots examined by the FAA between 2002 and 2012 who had had AF at some point during his or her medical history were reviewed, and those with an initial stroke or transient ischemic attack (TIA) during that time period were included in this study. All records were individually reviewed to determine stroke and AF history, medical certification history, and recurrent events. Variables collected included medical and behavior history, stroke type, gender, BMI, medication use, and any cardiovascular or neurological outcomes of interest. Major recurrent events included stroke, TIA, cerebrovascular accident, death, or other major events. These factors were used to calculate CHA2DS2-VASc scores.RESULTS: Of the 141 pilots selected for the study, 17.7% experienced a recurrent event. At 6 mo, the recurrent event rate was 5.0%; at 1 yr, 5.8%; at 3 yr 6.9%; and at 5 yr the recurrent event rate was 17.3%. No statistical difference between CHA2DS2-VASc scores was found as it pertained to number of recurrent events.DISCUSSION: We found no significant factors predicting risk of recurrent event and lower recurrence rates in pilots than the general population. This suggests CHA2DS2-VASc scores are not appropriate risk stratification tools in an aviation population and more research is necessary to determine risk of recurrent events in aviators with atrial fibrillation.Tedford J, Skaggs V, Norris A, Sahiar F, Mathers C. Recurrent stroke risk in pilots with atrial fibrillation. Aerosp Med Hum Perform. 2020; 91(4):352–357.


2010 ◽  
Vol 4 (1) ◽  
pp. 70-82 ◽  
Author(s):  
Arno Böhler

Nietzsche's model of eternal return triggers a drama of affirmation, the overcoming of a simple miming of our ancestors in favour of an active participation in the counter-actualisation of hidden potentials in recurrent events. Based on a close study of Zarathustra's struggle to free himself from a suffocating nihilism, the paper focuses on the revelatory caesura that ushers in what Deleuze calls the third synthesis of time, a time of ‘doing’ rather than reflection.


2015 ◽  
Vol 1 (1) ◽  
pp. 127-132
Author(s):  
Stephen Hugh-Jones

The previous paper was first published in 1982, when ethnoastronomy was still in its infancy. It appeared in Ethnoastronomy and Archaeoastronomy in the American Tropics, Tony Aveni and Gary Urton’s edited proceedings of an international conference held at the American Museum of Natural History’s Hayden Planetarium in New York under the auspices of the New York Academy of Sciences. Aveni and Urton were true pioneers who opened up a new interdisciplinary field of research that brought together astronomers, anthropologists, archaeologists, historians and others, all interested in astronomical knowledge amongst contemporary indigenous societies, in how buildings, settlements and archaeological monuments were aligned with recurrent events in the sky, and in how such alignments matched up with astronomical information contained in ancient codices and other historical documents and in contemporary ethnographic accounts.


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