scholarly journals Using predictions from a joint model for longitudinal and survival data to inform the optimal time of intervention in an abdominal aortic aneurysm screening programme

2017 ◽  
Vol 59 (6) ◽  
pp. 1247-1260 ◽  
Author(s):  
Michael J. Sweeting
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Survival Data ◽  
Screening Programme ◽  
Joint Model ◽  
Optimal Time ◽  
Abdominal Aortic ◽  
Longitudinal And Survival Data ◽  
Time Of Intervention

scholarly journals Outcomes in Men From the NHS Abdominal Aortic Aneurysm Screening Programme With a Large Aneurysm Referred for Intervention

2021 ◽  
Vol 73 (3) ◽  
pp. 1108
Author(s):  
L. Meecham ◽  
J. Jacomelli ◽  
M. Davis ◽  
A. Pherwani ◽  
T. Lees ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Screening Programme ◽  
Abdominal Aortic ◽  
Large Aneurysm

Abdominal aortic aneurysm screening programme

2019 ◽  
Vol 13 (9) ◽  
pp. 430-434
Author(s):  
Ian Peate
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Abdominal Aorta ◽  
Screening Programme ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Ultrasound Scan ◽  
Abdominal Aneurysm ◽  
Abdominal Aortic ◽  
The Uk

This is the second article in a series of articles regarding screening programmes. In this article, an overview of the abdominal aorta is provided. The article also considers the abdominal aortic aneurysm screening programme. Aortic abdominal aneurysm is described. The majority of abdominal aortic aneurysms are asymptomatic; however, if there are any symptoms, these are explained. All four UK countries offer men aged 65 years and over a screening opportunity using an ultrasound scan, the fundamental aspects of abdominal aortic aneurysm screening programmes is offered. It is emphasised that screening is not mandatory in the UK; the man has a right to decline the invitation to attend any screening programme.

OXFORD SCREENING PROGRAMME FOR ABDOMINAL AORTIC ANEURYSM IN MEN AGED 65 TO 74 YEARS

The Lancet ◽  
1988 ◽  
Vol 332 (8611) ◽  
pp. 613-615 ◽  
Author(s):  
Jack Collin ◽  
Jackie Walton ◽  
Leandro Araujo ◽  
David Lindsell
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Screening Programme ◽  
Abdominal Aortic

scholarly journals Retrospective review of abdominal aortic aneurysm deaths in New Zealand: what proportion of deaths is potentially preventable by a screening programme in the contemporary setting?

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e027291
Author(s):  
Wing Cheuk Chan ◽  
Dean Papaconstantinou ◽  
Doone Winnard ◽  
Gary Jackson
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
New Zealand ◽  
Aortic Aneurysm ◽  
Screening Programme ◽  
Population Based ◽  
Cross Sectional ◽  
The People ◽  
Abdominal Aortic ◽  
High Prevalence ◽  
History Of

ObjectivesTo describe the proportions of people dying from abdominal aortic aneurysm (AAA) who might have benefited from a formal screening programme for AAA.DesignRetrospective cross-sectional review of deaths.Setting and study populationsAll AAA deaths registered in New Zealand from 2010 to 2014 in the absence of a national AAA screening programme.Main outcome measuresKnown history of AAA prior to the acute event leading to AAA death, prognosis limiting comorbidities, history of prior abdominal imaging and a validated multimorbidity measure (M3-index scores).Results1094 AAA deaths were registered in the 5 years between 2010 and 2014 in New Zealand. Prior to the acute AAA event resulting in death, 31.3% of the cohort had a known AAA diagnosis, and 10.9% had a previous AAA procedure. On average, the AAA diagnosis was known 3.7 years prior to death. At least 77% of the people dying from AAA also had one or more other prognosis limiting diagnosis. The hazard of 1-year mortality associated with the non-AAA related comorbidities for the AAA cohort aged 65 or above were 1.5–2.6 times higher than to the age matched general population based on M3-index scores. In 2014, overall AAA deaths accounted for only 0.7% of total deaths, and 1.0% of deaths among men aged 65 or above in New Zealand. At most, 20% of people dying from AAA in New Zealand between 2010 and 2014 might have had the potential to derive full benefit from a screening programme. About 51% of cases would have derived no or very limited benefit from a screening programme.ConclusionFalling AAA mortality, and high prevalence of competing comorbidities and/or prior AAA diagnosis and procedure raises the question about the likely value of a national AAA screening programme in a country such as New Zealand.

Aortic Anatomic Severity Grade Correlates with Midterm Mortality in Patients Undergoing Abdominal Aortic Aneurysm Repair

2019 ◽  
Vol 53 (4) ◽  
pp. 292-296 ◽  
Author(s):  
Zane Z. Young ◽  
Mark D. Balceniuk ◽  
Khurram Rasheed ◽  
Doran Mix ◽  
Antoinette Esce ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Resource Utilization ◽  
Survival Data ◽  
Abdominal Aortic Aneurysm Repair ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Severity Grade ◽  
Abdominal Aortic ◽  
Receiver Operator Curve Analysis

Background: Anatomic severity grade (ASG) can be used to assess abdominal aortic aneurysm (AAA) anatomic complexity. High ASG is associated with complications following endovascular repair of AAAs and we have demonstrated that ASG correlates with resource utilization. The hypothesis of this study is that ASG is directly related to midterm mortality in patients undergoing AAA repair. Methods: Patients who underwent infrarenal AAA repairs between July 2007 and August 2014 were retrospectively reviewed and ASG scores were calculated using 3-dimensional computed tomography reconstructions. Perioperative mortalities (≤30 days) were excluded. The ASG value of 15 was chosen based on previous receiver–operator curve analysis, which showed that an ASG of 15 was predictive of postoperative complications and resource utilization. The 5-year survivors and mortalities were compared utilizing comorbidities, pharmacologic variables, and anatomic variables at or above the defined threshold. Results: A total of 402 patients (80% male and 96% Caucasian) with complete anatomic and survival data were included in the analysis. Mean ASG and age at the time of repair were 16 ± 0.15 and 73 ± 0.43 years old, respectively. The 5-year mortality was significantly associated with ASG >15 (hazard ratio [HR]: 1.504, confidence interval [CI]: 1.077-2.100, P < .017), hyperlipidemia (HR: 1.987, CI: 1.341-2.946, P < .001), coronary artery disease (HR: 1.432, CI: 1.037-1.978, P < .029), and chronic obstructive pulmonary disease (HR: 1.412, CI: 1.027-1.943, P < .034). Kaplan-Meier analysis demonstrated improved survival in the low score ASG ≤15 group at 1, 3, and 5 years (96% vs 93%, 81% vs 69%, and 53% vs 41%; P = .0182; Figure 1). Conclusions: Increasing aortic anatomic complexity as characterized by ASG >15 is an independent predictor of midterm mortality following elective infrarenal AAA repair. Therefore, it may be a useful tool for appropriate patient selection and risk stratification prior to elective infrarenal AAA repair.

Impact of the first 5 years of a national abdominal aortic aneurysm screening programme

2016 ◽  
Vol 103 (9) ◽  
pp. 1125-1131 ◽  
Author(s):  
J. Jacomelli ◽  
L. Summers ◽  
A. Stevenson ◽  
T. Lees ◽  
J. J. Earnshaw
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Screening Programme ◽  
Abdominal Aortic

Abdominal aortic aneurysm disease: health risks, management and screening

Clinical Risk ◽  
2008 ◽  
Vol 14 (6) ◽  
pp. 208-210
Author(s):  
Hany Hafez
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Health Risks ◽  
Screening Programme ◽  
Non Invasive ◽  
Invasive Test ◽  
Department Of Health ◽  
Abdominal Aortic ◽  
Reduction Of Mortality ◽  
The Impact

Abdominal aortic aneurysm (AAA) disease is a condition that affects mainly men over the age of 65 years. The majority of AAAs will remain asymptomatic and therefore undetected. These undetected aneurysms will invariably grow enough for their walls to rupture leading to death in nearly 75% of those affected. Ultrasound-based AAA screening has been shown to reduce the risk of dying of an AAA by half. This significant reduction of mortality offered by a simple and sensitive non-invasive test has prompted the Department of Health to introduce a national AAA screening programme for England and Wales. In this article, the public health risks of AAA disease together with details of the impact of the anticipated national AAA screening programme are discussed.

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