S38.4: Helicobacter pylori acquisition in infancy: first results of a prospective birth cohort study from Germany

2004 ◽  
Vol 46 (S1) ◽  
pp. 82-82
Author(s):  
Dietrich Rothenbacher ◽  
Maria Weyermann ◽  
Günter Bode ◽  
Murrat Kulaksiz ◽  
Guido Adler ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Cohort Study ◽  
Birth Cohort ◽  
Birth Cohort Study ◽  
First Results ◽  
Prospective Birth Cohort ◽  
Prospective Birth Cohort Study

scholarly journals Daycare attendance and respiratory tract infections: a prospective birth cohort study

BMJ Open ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. e014635 ◽  
Author(s):  
Linnea Schuez-Havupalo ◽  
Laura Toivonen ◽  
Sinikka Karppinen ◽  
Anne Kaljonen ◽  
Ville Peltola
Keyword(s):  
Cohort Study ◽  
Respiratory Tract ◽  
Birth Cohort ◽  
Day Care ◽  
Repeated Measures ◽  
Respiratory Tract Infections ◽  
Birth Cohort Study ◽  
Tract Infections ◽  
Prospective Birth Cohort ◽  
Prospective Birth Cohort Study

ObjectiveWe explored the burden of respiratory tract infections (RTIs) in young children with regard to day-care initiation.DesignLongitudinal prospective birth cohort study.Setting and methodsWe recruited 1827 children for follow-up until the age of 24 months collecting diary data on RTIs and daycare. Children with continuous daycare type and complete data were divided into groups of centre-based daycare (n=299), family day care (FDC) (n=245) and home care (n=350). Using repeated measures variance analyses, we analysed days per month with symptoms of respiratory tract infection, antibiotic treatments and parental absence from work for a period of 6 months prior to and 9 months after the start of daycare.ResultsWe documented a significant effect of time and type of daycare, as well as a significant interaction between them for all outcome measures. There was a rise in mean days with symptoms from 3.79 (95% CI 3.04 to 4.53) during the month preceding centre-based daycare to 10.57 (95% CI 9.35 to 11.79) at 2 months after the start of centre-based daycare, with a subsequent decrease within the following 9 months. Similar patterns with a rise and decline were observed in the use of antibiotics and parental absences. The start of FDC had weaker effects. Our findings were not changed when taking into account confounding factors.ConclusionsOur study shows the rapid increase in respiratory infections after start of daycare and a relatively fast decline in the course of time with continued daycare. It is important to support families around the beginning of daycare.

scholarly journals Association between breast feeding and asthma in 6 year old children: findings of a prospective birth cohort study

BMJ ◽  
1999 ◽  
Vol 319 (7213) ◽  
pp. 815-819 ◽  
Author(s):  
W H Oddy ◽  
P G Holt ◽  
P D Sly ◽  
A W Read ◽  
L I Landau ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Breast Feeding ◽  
Birth Cohort Study ◽  
Prospective Birth Cohort ◽  
Prospective Birth Cohort Study

Early Predictors of Eating Problems in Preadolescence—A Prospective Birth Cohort Study

2016 ◽  
Vol 58 (5) ◽  
pp. 533-542 ◽  
Author(s):  
Anja Munkholm ◽  
Else Marie Olsen ◽  
Charlotte Ulrikka Rask ◽  
Lars Clemmensen ◽  
Martin K. Rimvall ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Birth Cohort Study ◽  
Eating Problems ◽  
Early Predictors ◽  
Prospective Birth Cohort ◽  
Prospective Birth Cohort Study

Maternal Glycemia during pregnancy and Early Offspring Development: A Prospective Birth Cohort Study

2021 ◽  
Author(s):  
Peng Wang ◽  
Jun Xie ◽  
Xue-chun Jiao ◽  
Shuang-shuang Ma ◽  
Yang Liu ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Plasma Glucose ◽  
Birth Cohort Study ◽  
Neurodevelopmental Outcomes ◽  
Glucose Levels ◽  
Maternal Glucose Levels ◽  
Prospective Birth Cohort ◽  
Maternal Glucose ◽  
Prospective Birth Cohort Study

Abstract Context The association of maternal gestational diabetes mellitus (GDM) with neurodevelopmental outcomes remains controversial and evidence that maternal increasing levels of glucose during pregnancy associated with the risk for impaired neurodevelopment were limited. Objective To identify the continuous association of increasing maternal glucose levels with neurodevelopmental disorders in offspring and explore the potential contribution of cord metabolites to this association. Methods The prospective birth cohort study included 1036 mother-child pairs. Primary predictors were maternal exposure GDM and maternal glucose values at a 75-g oral-glucose-tolerance test (OGTT) at 24–28 weeks during pregnancy. Primary neurodevelopmental outcomes at 12 mo in offspring were assessed by the ASQ-3. Results Maternal GDM was associated with failing the communication domain in offspring in the adjusted models [RR with 95% CI: 1.97(1.11, 3.52)]. Increasing levels of fasting plasma glucose (FPG), 1 h plasma glucose (1-h PG) and 2 h plasma glucose (2-h PG) with one SD change were at higher risks in failing the personal social domain of ASQ [RRs with 95% CI for FPG: 1.49(1.09, 2.04); for 1-h PG: 1.70(1.27, 2.29); for 2-h PG: 1.36(1.01, 1.84)]. The linear association was also demonstrated. Compared with girls, boys exposed to higher maternal glucose levels were inclined to the failure of the personal social domain. Mediation analysis showed the contribution of maternal GDM to failure of communication domain mediated by C-peptide. Conclusions Maternal glucose levels below those diagnostic of diabetes are continuously associated with impaired neurodevelopment in offspring at 12 mo.

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