scholarly journals Collective cell migration driven by filopodia—New insights from the social behavior of myotubes

BioEssays ◽  
2021 ◽  
pp. 2100124
Author(s):  
Maik C. Bischoff ◽  
Sven Bogdan
Keyword(s):  
Cell Migration ◽  
Social Behavior ◽  
Collective Cell Migration ◽  
The Social

Collective Cell Migration: A Mechanistic Perspective

Physiology ◽  
2013 ◽  
Vol 28 (6) ◽  
pp. 370-379 ◽  
Author(s):  
Sri Ram Krishna Vedula ◽  
Andrea Ravasio ◽  
Chwee Teck Lim ◽  
Benoit Ladoux
Keyword(s):  
Wound Healing ◽  
Cell Migration ◽  
Social Behavior ◽  
Cancer Metastasis ◽  
Collective Cell Migration ◽  
Biological Processes ◽  
The Social ◽  
Holistic Understanding ◽  
Broad Overview

Collective cell migration is fundamental to gaining insights into various important biological processes such as wound healing and cancer metastasis. In particular, recent in vitro studies and in silico simulations suggest that mechanics can explain the social behavior of multicellular clusters to a large extent with minimal knowledge of various cellular signaling pathways. These results suggest that a mechanistic perspective is necessary for a comprehensive and holistic understanding of collective cell migration, and this review aims to provide a broad overview of such a perspective.

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