Eukaryotes without oxygen? A review of “Mitochondria and anaerobic energy metabolism in eukaryotes” by William F. Martin, Aloysius G. M. Tielens and Marek Mentel

BioEssays ◽  
2021 ◽  
pp. 2100105
Author(s):  
Dave Speijer
Keyword(s):  
Energy Metabolism ◽  
Anaerobic Energy

Metabolomic profiling of anaerobic and aerobic energy metabolic pathways in chronic obstructive pulmonary disease

2021 ◽  
pp. 153537022110088
Author(s):  
Mingshan Xue ◽  
Yifeng Zeng ◽  
Runpei Lin ◽  
Hui-Qi Qu ◽  
Teng Zhang ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Energy Metabolism ◽  
Pulmonary Disease ◽  
Metabolic Pathways ◽  
Energy Supply ◽  
Stable Phase ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Anaerobic Energy

While there is no cure for chronic obstructive pulmonary disease (COPD), its progressive nature and the formidable challenge to manage its symptoms warrant a more extensive study of the pathogenesis and related mechanisms. A new emphasis on COPD study is the change of energy metabolism. For the first time, this study investigated the anaerobic and aerobic energy metabolic pathways in COPD using the metabolomic approach. Metabolomic analysis was used to investigate energy metabolites in 140 COPD patients. The significance of energy metabolism in COPD was comprehensively explored by the Global Initiative for Chronic Obstructive Lung Disease–GOLD grading, acute exacerbation vs. stable phase (either clinical stability or four-week stable phase), age group, smoking index, lung function, and COPD Assessment Test (CAT) score. Through comprehensive evaluation, we found that COPD patients have a significant imbalance in the aerobic and anaerobic energy metabolisms in resting state, and a high tendency of anaerobic energy supply mechanism that correlates positively with disease progression. This study highlighted the significance of anaerobic and low-efficiency energy supply pathways in lung injury and linked it to the energy-inflammation-lung ventilatory function and the motion limitation mechanism in COPD patients, which implies a novel therapeutic direction for this devastating disease.

Anaerobic energy metabolism of the European eel,Anguilla anguilla L.

1983 ◽  
Vol 149 (4) ◽  
pp. 469-475 ◽  
Author(s):  
Aren van Waarde ◽  
Guido van den Thillart ◽  
Fanja Kesbeke
Keyword(s):  
Energy Metabolism ◽  
Anguilla Anguilla ◽  
European Eel ◽  
Anaerobic Energy

scholarly journals Biochemistry and Evolution of Anaerobic Energy Metabolism in Eukaryotes

2012 ◽  
Vol 76 (2) ◽  
pp. 444-495 ◽  
Author(s):  
M. Muller ◽  
M. Mentel ◽  
J. J. van Hellemond ◽  
K. Henze ◽  
C. Woehle ◽  
...  
Keyword(s):  
Energy Metabolism ◽  
Anaerobic Energy

Anaerobic Energy Metabolism in Brain Tumors1

2015 ◽  
pp. 163-191 ◽  
Author(s):  
W. M. Kirsch ◽  
D. Schulz ◽  
J. Van Buskirk ◽  
P. Nakane
Keyword(s):  
Energy Metabolism ◽  
Anaerobic Energy

The facultative anaerobic energy metabolism of Schistosoma mansoni sporocysts

1992 ◽  
Vol 56 (1) ◽  
pp. 49-57 ◽  
Author(s):  
Aloysius G.M. Tielens ◽  
Anja M.C. Horemans ◽  
Ramon Dunnewijk ◽  
Pieter van der Meer ◽  
Simon G. van den Bergh
Keyword(s):  
Energy Metabolism ◽  
Schistosoma Mansoni ◽  
Anaerobic Energy ◽  
Facultative Anaerobic
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