Single-pulsed electromagnetic field therapy increases osteogenic differentiation through Wnt signaling pathway and sclerostin downregulation

2015 ◽  
Vol 36 (7) ◽  
pp. 494-505 ◽  
Author(s):  
Chih-Chun Lin ◽  
Ru-Wei Lin ◽  
Chih-Wei Chang ◽  
Gwo-Jaw Wang ◽  
Kuo-An Lai
Keyword(s):  
Electromagnetic Field ◽  
Wnt Signaling ◽  
Osteogenic Differentiation ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Pulsed Electromagnetic Field ◽  
Field Therapy ◽  
Pulsed Electromagnetic ◽  
Pulsed Electromagnetic Field Therapy

scholarly journals Effect of Pulsed Electromagnetic Field on Bone Formation and Lipid Metabolism of Glucocorticoid-Induced Osteoporosis Rats through Canonical Wnt Signaling Pathway

2016 ◽  
Vol 2016 ◽  
pp. 1-13 ◽  
Author(s):  
Yuan Jiang ◽  
Hui Gou ◽  
Sanrong Wang ◽  
Jiang Zhu ◽  
Si Tian ◽  
...  
Keyword(s):  
Electromagnetic Field ◽  
Lipid Metabolism ◽  
Bone Formation ◽  
Wnt Signaling ◽  
Signaling Pathway ◽  
Wnt Signaling Pathway ◽  
Pulsed Electromagnetic Field ◽  
Canonical Wnt Signaling ◽  
Pulsed Electromagnetic ◽  
Canonical Wnt

Pulsed electromagnetic field (PEMF) has been suggested as a promising method alternative to drug-based therapies for treating osteoporosis (OP), but the role of PEMF in GIOP animal models still remains unknown. This study was performed to investigate the effect of PEMF on bone formation and lipid metabolism and further explored the several important components and targets of canonical Wnt signaling pathway in GIOP rats. After 12 weeks of intervention, bone mineral density (BMD) level of the whole body increased significantly, serum lipid levels decreased significantly, and trabeculae were thicker in GIOP rats of PEMF group. PEMF stimulation upregulated the mRNA and protein expression of Wnt10b, LRP5,β-catenin, OPG, and Runx2 and downregulated Axin2, PPAR-γ, C/EBPα, FABP4, and Dkk-1. The results of this study suggested that PEMF stimulation can prevent bone loss and improve lipid metabolism disorders in GIOP rats. Canonical Wnt signaling pathway plays an important role in bone formation and lipid metabolism during PEMF stimulation.

Low-frequency Pulsed Electromagnetic Field Therapy in Fibromyalgia

2009 ◽  
Vol 25 (8) ◽  
pp. 722-728 ◽  
Author(s):  
Serap Tomruk Sutbeyaz ◽  
Nebahat Sezer ◽  
Fusun Koseoglu ◽  
Sibel Kibar
Keyword(s):  
Electromagnetic Field ◽  
Low Frequency ◽  
Pulsed Electromagnetic Field ◽  
Field Therapy ◽  
Pulsed Electromagnetic ◽  
Pulsed Electromagnetic Field Therapy

The Effect of Pulsed Electromagnetic Field on Patients with Endocrine Ophthalmopathy

1998 ◽  
Vol 8 (4) ◽  
pp. 253-257
Author(s):  
J. Jankauskienė ◽  
A. Paunksnis ◽  
A Blužienė ◽  
J. Saulgozis
Keyword(s):  
Electromagnetic Field ◽  
Optic Nerve ◽  
Soft Tissue ◽  
Nerve Function ◽  
Pulsed Electromagnetic Field ◽  
Ocular Movements ◽  
Endocrine Ophthalmopathy ◽  
Field Therapy ◽  
Pulsed Electromagnetic ◽  
Pulsed Electromagnetic Field Therapy

Purpose To evaluate eye signs, proptosis and ocular movements in patients with endocrine ophthalmopathy under the influence of pulsed electromagnetic field therapy. Methods We examined 14 patients (9 women, 5 men) with endocrine ophthalmopathy and evaluated eye signs, proptosis and ocular movements before and after the course of pulsed electromagnetic field therapy, and 12 controls. Their age ranged from 29 to 57 years. Visual sensitivity was investigated with a static automatic perimeter (Allergan Humphrey Field Analyzer). The score was calculated by rating the severity of involvement of soft tissue, proptosis, extraocular movements, corneal state and optic nerve function on a scale from 0 to 3. The pulsed electromagnetic field procedures were carried out with the help of electromagnetic spectacles. Results Pulsed electromagnetic field therapy reduced the score for soft tissue and proptosis in patients who suffered from endocrine ophthalmopathy. There was fall in the mean score for ocular movements, corneal and optic nerve function but it did not reach significance after treatment. Electromagnetic field therapy has no useful effect on visual signs and eye movements in two patients who had had the illness more than two years. Conclusions Localised pulsed electromagnetic field procedures can be recommended, together with other methods of conservative treatment of endocrine ophthalmopathy.

PULSED ELECTROMAGNETIC FIELD THERAPY OF PERSISTENT ROTATOR CUFF TENDINITIS

The Lancet ◽  
1984 ◽  
Vol 323 (8379) ◽  
pp. 695-698 ◽  
Author(s):  
Allan Binder ◽  
Graham Parr ◽  
Brian Hazleman ◽  
Sylvia Fitton-Jackson
Keyword(s):  
Electromagnetic Field ◽  
Rotator Cuff ◽  
Pulsed Electromagnetic Field ◽  
Rotator Cuff Tendinitis ◽  
Field Therapy ◽  
Pulsed Electromagnetic ◽  
Pulsed Electromagnetic Field Therapy
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