Pulsed electromagnetic field stimulation of bone marrow cells derived from ovariectomized rats affects osteoclast formation and local factor production

2004 ◽  
Vol 25 (2) ◽  
pp. 134-141 ◽  
Author(s):  
Kyle Chang ◽  
Walter Hong-Shong Chang ◽  
Yen-Hsin Yu ◽  
Chung Shih
Keyword(s):  
Bone Marrow ◽  
Electromagnetic Field ◽  
Bone Marrow Cells ◽  
Osteoclast Formation ◽  
Ovariectomized Rats ◽  
Field Stimulation ◽  
Pulsed Electromagnetic Field ◽  
Local Factor ◽  
Pulsed Electromagnetic ◽  
Stimulation Of

scholarly journals Alterations of Hematologic and Hematopoietic Parameters in Mice Exposed to Pulsed Electromagnetic Field

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Kangchu Li ◽  
Zenghui Teng ◽  
Zhaohui Liu ◽  
Yuxing Zhang ◽  
Kaiping Long ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Electromagnetic Field ◽  
Blood Cells ◽  
Bone Marrow Cells ◽  
Exposed Group ◽  
Control Group ◽  
Pulsed Electromagnetic Field ◽  
Gm Csf ◽  
Pulsed Electromagnetic ◽  
Marrow Cells

Effects of pulsed electromagnetic field (PEMF) on hematology and hematopoiesis might vary with different PEMF parameters. The purpose of this study was to evaluate the possible effects of PEMF exposure at different pulses on hematologic and hematopoietic parameters in mice. Groups of male BALB/c mice were whole body exposed or were sham exposed (control) to PEMF at 100, 1000, and 10000 pulses. After PEMF exposure, blood samples and bone marrow cells of mice were collected for hematologic examinations, bone marrow nucleated cell counting, colony-forming units of granulocyte-macrophage (CFU-GM) colony assay, and serum granulocyte-macrophage colony-stimulating factor (GM-CSF) assay. Compared with the control group, white blood cells (WBC) and lymphocytes (LYM) in the 100 and 1000 pulses exposed groups were significantly increased but not changed in the 10000 pulses exposed group. Red blood cells (RBC), hemoglobin (HGB), and platelets (PLT) were not changed in all exposed groups. There was no significant difference in mouse bone marrow nucleated cell number between the control group and each exposed group 7 days after PEMF exposure. The CFU-GM clone number of bone marrow cells and serum GM-CSF level were significantly increased in the 100 and 1000 pulses exposed group but not changed in the 10000 pulses exposed group. Our results indicated that the PEMF exposure at fewer pulses may induce statistically significant alterations in some hematologic and hematopoietic parameters of mice but no changes can be found in the more pulses PEMF-exposed groups.

Pulsed Electromagnetic Field Stimulation of Intervertebral Disc Cells

2014 ◽  
Vol 4 (1_suppl) ◽  
pp. s-0034-1376767-s-0034-1376767
Author(s):  
Stephen J. Ferguson ◽  
Alfredo Franco-Obregón ◽  
Karin Wuertz
Keyword(s):  
Electromagnetic Field ◽  
Intervertebral Disc ◽  
Field Stimulation ◽  
Pulsed Electromagnetic Field ◽  
Disc Cells ◽  
Pulsed Electromagnetic ◽  
Stimulation Of

Magnetic Field Visualization in Applications to Pulsed Electromagnetic Field Stimulation of Tissues

2003 ◽  
Vol 31 (2) ◽  
pp. 195-206 ◽  
Author(s):  
Maciej Zborowski ◽  
Ronald J. Midura ◽  
Alan Wolfman ◽  
Thomas Patterson ◽  
Michael Ibiwoye ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Electromagnetic Field ◽  
Field Stimulation ◽  
Pulsed Electromagnetic Field ◽  
Pulsed Electromagnetic ◽  
Stimulation Of

scholarly journals Pulsed electromagnetic field stimulation may improve fusion rates in cervical arthrodesis in high-risk populations

2018 ◽  
Vol 7 (2) ◽  
pp. 124-130 ◽  
Author(s):  
D. Coric ◽  
D. E. Bullard ◽  
V. V. Patel ◽  
J. T. Ryaby ◽  
B. L. Atkinson ◽  
...  
Keyword(s):  
Electromagnetic Field ◽  
Risk Factor ◽  
High Risk ◽  
Clinical Risk Factor ◽  
Field Stimulation ◽  
Pulsed Electromagnetic Field ◽  
Exact Test ◽  
High Risk Populations ◽  
Pulsed Electromagnetic ◽  
Pemf Treatment

Objectives Pulsed electromagnetic field (PEMF) stimulation was evaluated after anterior cervical discectomy and fusion (ACDF) procedures in a randomized, controlled clinical study performed for United States Food and Drug Administration (FDA) approval. PEMF significantly increased fusion rates at six months, but 12-month fusion outcomes for subjects at elevated risk for pseudoarthrosis were not thoroughly reported. The objective of the current study was to evaluate the effect of PEMF treatment on subjects at increased risk for pseudoarthrosis after ACDF procedures. Methods Two evaluations were performed that compared fusion rates between PEMF stimulation and a historical control (160 subjects) from the FDA investigational device exemption (IDE) study: a post hoc (PH) analysis of high-risk subjects from the FDA study (PH PEMF); and a multicentre, open-label (OL) study consisting of 274 subjects treated with PEMF (OL PEMF). Fisher’s exact test and multivariate logistic regression was used to compare fusion rates between PEMF-treated subjects and historical controls. Results In separate comparisons of PH PEMF and OL PEMF groups to the historical control group, PEMF treatment significantly (p < 0.05, Fisher’s exact test) increased the fusion rate at six and 12 months for certain high-risk subjects who had at least one clinical risk factor of being elderly, a nicotine user, osteoporotic, or diabetic; and for those with at least one clinical risk factor and who received at least a two- or three-level arthrodesis. Conclusion Adjunctive PEMF treatment can be recommended for patients who are at high risk for pseudoarthrosis. Cite this article: D. Coric, D. E. Bullard, V. V. Patel, J. T. Ryaby, B. L. Atkinson, D. He, R. D. Guyer. Pulsed electromagnetic field stimulation may improve fusion rates in cervical arthrodesis in high-risk populations. Bone Joint Res 2018;7:124–130. DOI: 10.1302/2046-3758.72.BJR-2017-0221.R1.

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