KRN633, an Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinase, Induces Intrauterine Growth Restriction in Mice

Naomichi Abe; Tsutomu Nakahara; Akane Morita; Yoshiko Wada; Asami Mori; Kenji Sakamoto; Tohru Nagamitsu; Kunio Ishii

doi:10.1002/bdrb.21064

KRN633, an Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinase, Induces Intrauterine Growth Restriction in Mice

Birth Defects Research Part B Developmental and Reproductive Toxicology ◽

10.1002/bdrb.21064 ◽

2013 ◽

Vol 98 (4) ◽

pp. 297-303 ◽

Cited By ~ 5

Author(s):

Naomichi Abe ◽

Tsutomu Nakahara ◽

Akane Morita ◽

Yoshiko Wada ◽

Asami Mori ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Intrauterine Growth Restriction ◽

Growth Factor Receptor ◽

Growth Restriction ◽

Vascular Endothelial ◽

Intrauterine Growth ◽

Endothelial Growth Factor

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Treatment of Mid-Pregnant Mice with KRN633, an Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinase, Induces Abnormal Retinal Vascular Patterning in Their Newborn Pups

Birth Defects Research Part B Developmental and Reproductive Toxicology ◽

10.1002/bdrb.21112 ◽

2014 ◽

Vol 101 (4) ◽

pp. 293-299 ◽

Cited By ~ 4

Author(s):

Akane Morita ◽

Tsutomu Nakahara ◽

Naomichi Abe ◽

Yuki Kurauchi ◽

Asami Mori ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Vascular Patterning ◽

Pregnant Mice ◽

Endothelial Growth Factor

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Everolimus zur Behandlung des metastasierten Nierenzellkarzinoms nach Versagen der ersten VEGFr-TKI(Vascular Endothelial Growth Factor Receptor-Tyrosine Kinase Inhibitor)-Therapie: Ergebnisse einer Interimsanalyse einer nichtinterventionellen Studie

Karger Kompass Onkologie ◽

10.1159/000356898 ◽

2014 ◽

Vol 1 (1) ◽

pp. 28-29

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Receptor Tyrosine Kinase Inhibitor ◽

Endothelial Growth Factor

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Placental expression of vascular endothelial growth factor in placentae from pregnancies complicated by pre-eclampsia and intrauterine growth restriction does not support placental hypoxia at delivery

Placenta ◽

10.1016/s0143-4004(97)80061-6 ◽

1997 ◽

Vol 18 (4) ◽

pp. 269-276 ◽

Cited By ~ 114

Author(s):

F. Lyall ◽

A. Young ◽

F. Boswell ◽

J.C.P. Kingdom ◽

I.A. Greer

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Intrauterine Growth Restriction ◽

Growth Restriction ◽

Vascular Endothelial ◽

Intrauterine Growth ◽

Endothelial Growth Factor

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Hepatotoxicity of vascular endothelial growth factor receptor tyrosine kinase inhibitors: clinical practice and evidence

Drugs & Therapy Perspectives ◽

10.1007/s40267-017-0416-8 ◽

2017 ◽

Vol 33 (8) ◽

pp. 395-402

Author(s):

Bulent Cetin ◽

Irem Bilgetekin ◽

Mustafa Cengiz ◽

Ahmet Ozet

Keyword(s):

Vascular Endothelial Growth Factor ◽

Clinical Practice ◽

Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Endothelial Growth Factor ◽

Receptor Tyrosine Kinase Inhibitors

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Inhibition of choroidal neovascularization by blocking vascular endothelial growth factor receptor tyrosine kinase

Japanese Journal of Ophthalmology ◽

10.1007/s10384-007-0506-6 ◽

2008 ◽

Vol 52 (2) ◽

pp. 91-98 ◽

Cited By ~ 25

Author(s):

Junko Kami ◽

Kimimasa Muranaka ◽

Yasuo Yanagi ◽

Ryo Obata ◽

Yasuhiro Tamaki ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Choroidal Neovascularization ◽

Receptor Tyrosine Kinase ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Endothelial Growth Factor

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Inhibition of Chronic and Acute Skin Inflammation by Treatment with a Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor

American Journal Of Pathology ◽

10.2353/ajpath.2008.071074 ◽

2008 ◽

Vol 173 (1) ◽

pp. 265-277 ◽

Cited By ~ 59

Author(s):

Cornelia Halin ◽

Hermann Fahrngruber ◽

Josef G. Meingassner ◽

Guido Bold ◽

Amanda Littlewood-Evans ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Skin Inflammation ◽

Vascular Endothelial ◽

Endothelial Growth Factor

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Naphthamides as Novel and Potent Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors: Design, Synthesis, and Evaluation¶

Journal of Medicinal Chemistry ◽

10.1021/jm701097z ◽

2008 ◽

Vol 51 (6) ◽

pp. 1649-1667 ◽

Cited By ~ 43

Author(s):

Jean-Christophe Harmange ◽

Matthew M. Weiss ◽

Julie Germain ◽

Anthony J. Polverino ◽

George Borg ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Kinase Inhibitors ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Design Synthesis ◽

Endothelial Growth Factor ◽

Receptor Tyrosine Kinase Inhibitors

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AB0168 Therapeutic effects of sunitinib, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, in a murine arthritis model

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2012-eular.168 ◽

2013 ◽

Vol 71 (Suppl 3) ◽

pp. 647.5-647

Author(s):

K. Furuya ◽

Y. Kaku ◽

K. Yoshida ◽

K. Joh ◽

D. Kurosaka

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Growth Factor Receptor ◽

Therapeutic Effects ◽

Vascular Endothelial ◽

Arthritis Model ◽

Endothelial Growth Factor

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Enhanced Susceptibility of Irradiated Tumor Vessels to Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibition

Cancer Research ◽

10.1158/0008-5472.can-04-3379 ◽

2005 ◽

Vol 65 (12) ◽

pp. 5374-5379 ◽

Cited By ~ 38

Author(s):

Daniel Zips ◽

Wolfgang Eicheler ◽

Peter Geyer ◽

Franziska Hessel ◽

Annegret Dörfler ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Receptor Tyrosine Kinase ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Kinase Inhibition ◽

Tumor Vessels ◽

Tyrosine Kinase Inhibition ◽

Endothelial Growth Factor

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Antiangiogenic Effects of Axitinib, an Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinase, on Laser-Induced Choroidal Neovascularization in Mice

Current Eye Research ◽

10.3109/02713683.2012.727520 ◽

2012 ◽

Vol 38 (1) ◽

pp. 119-127 ◽

Cited By ~ 8

Author(s):

Seungbum Kang ◽

Chang Rae Roh ◽

Won-Kyung Cho ◽

Ki Cheol Park ◽

Keum-Jin Yang ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Tyrosine Kinase ◽

Choroidal Neovascularization ◽

Receptor Tyrosine Kinase ◽

Growth Factor Receptor ◽

Vascular Endothelial ◽

Endothelial Growth Factor

Download Full-text