scholarly journals Population-based case-control study of the association between weather-related extreme heat events and neural tube defects

2017 ◽  
Vol 109 (18) ◽  
pp. 1482-1493 ◽  
Author(s):  
Aida Soim ◽  
Shao Lin ◽  
Scott C. Sheridan ◽  
Syni-An Hwang ◽  
Wan-Hsiang Hsu ◽  
...  
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Extreme Heat ◽  
Extreme Heat Events ◽  
Heat Events ◽  
Control Study

A population-based case–control study of the association between weather-related extreme heat events and low birthweight

2020 ◽  
pp. 1-8
Author(s):  
Wayne R. Lawrence ◽  
Aida Soim ◽  
Wangjian Zhang ◽  
Ziqiang Lin ◽  
Yi Lu ◽  
...  
Keyword(s):  
Case Control Study ◽  
First Trimester ◽  
Population Based ◽  
Case Control ◽  
Extreme Heat ◽  
Maximum Temperature ◽  
Extreme Heat Events ◽  
The Impact ◽  
Heat Events ◽  
Control Study

Abstract Although prenatal exposure to high ambient temperatures were reported to be associated with preterm birth, limited research assessed the impact of weather-related extreme heat events (EHE) on birthweight, particularly by trimester. We, therefore, investigated the impact of prenatal EHE on birthweight among term babies (tLBW) by trimester and birthweight percentile. We conducted a population-based case–control study on singleton live births at 38–42 gestational weeks in New York State (NYS) by linking weather data with NYS birth certificates. A total of 22,615 cases were identified as birthweight <2500 gram, and a random sample of 139,168 normal birthweight controls was included. EHE was defined as three consecutive days with the maximum temperatures of ≥32.2 °C/90 °F (EHE90) and two consecutive days of temperatures ≥97th percentile (EHE97) based on the distribution of the maximum temperature for the season and region. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) with multivariable unconditional logistic regression, controlling for confounders. Overall exposure to EHE97 for 2 d was associated with tLBW (OR 1.05; 95% CI 1.02, 1.09); however, the strongest associations were only observed in the first trimester for both heat indicators, especially when exposure was ≥3 d (ORs ranged: 1.06–1.13). EHE in the first trimester was associated with significant reduction in mean birthweight from 26.78 gram (EHE90) to 36.25 gram (EHE97), which mainly affected the 40th and 60th birthweight percentiles. Findings revealed associations between multiple heat indicators and tLBW, where the impact was consistently strongest in the first trimester.

scholarly journals A population‐based case–control study of the association between weather‐related extreme heat events and orofacial clefts

2018 ◽  
Vol 110 (19) ◽  
pp. 1468-1477
Author(s):  
Aida Soim ◽  
Scott C. Sheridan ◽  
Syni‐An Hwang ◽  
Wan‐Hsiang Hsu ◽  
Sarah C. Fisher ◽  
...  
Keyword(s):  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Extreme Heat ◽  
Orofacial Clefts ◽  
Extreme Heat Events ◽  
Heat Events ◽  
Control Study

A population-based case-control study of risk factors for neural tube defects in Shenyang, China

2010 ◽  
Vol 27 (1) ◽  
pp. 149-154 ◽  
Author(s):  
Zhihua Yin ◽  
Wei Xu ◽  
Changying Xu ◽  
Shiqi Zhang ◽  
Yajun Zheng ◽  
...  
Keyword(s):  
Risk Factors ◽  
Neural Tube ◽  
Neural Tube Defects ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study

Maternal Flu, Fever, and the Risk of Neural Tube Defects: A Population-based Case-Control Study

1994 ◽  
Vol 140 (3) ◽  
pp. 244-255 ◽  
Author(s):  
Michele C. Lynberg ◽  
Muin J. Khoury ◽  
Xinpei Lu ◽  
Teofil Cocian
Keyword(s):  
Neural Tube ◽  
Neural Tube Defects ◽  
Case Control Study ◽  
Population Based ◽  
Case Control ◽  
Control Study
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