Selective incorporation of asialofetuin into hepatocyte of rat

1985 ◽  
Vol 6 (4) ◽  
pp. 389-400 ◽  
Author(s):  
Yukihiko Aramaki ◽  
Asaichi Inaba ◽  
Seishi Tsuchiya
Keyword(s):  
Selective Incorporation

scholarly journals Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC

2007 ◽  
Vol 35 (15) ◽  
pp. 5154-5164 ◽  
Author(s):  
Daniela Castanotto ◽  
Kumi Sakurai ◽  
Robert Lingeman ◽  
Haitang Li ◽  
Louise Shively ◽  
...  
Keyword(s):  
Small Interfering Rnas ◽  
Selective Incorporation

scholarly journals A Tyrosine Motif in the Cytoplasmic Domain of Mason-Pfizer Monkey Virus Is Essential for the Incorporation of Glycoprotein into Virions

2003 ◽  
Vol 77 (9) ◽  
pp. 5192-5200 ◽  
Author(s):  
Chisu Song ◽  
Susan R. Dubay ◽  
Eric Hunter
Keyword(s):  
Amino Acid ◽  
Cytoplasmic Domain ◽  
Virus Infectivity ◽  
Fusion Activity ◽  
Tyrosine Residues ◽  
Glycoprotein Complex ◽  
Selective Incorporation ◽  
Uptake Studies ◽  
And Function ◽  
Immature Virus

ABSTRACT Mason-Pfizer monkey virus (M-PMV) encodes a transmembrane (TM) glycoprotein with a 38-amino-acid-long cytoplasmic domain. After the release of the immature virus, a viral protease-mediated cleavage occurs within the cytoplasmic domain, resulting in the loss of 17 amino acids from the carboxy terminus. This maturational cleavage occurs between a histidine at position 21 and a tyrosine at position 22 in the cytoplasmic domain of the TM protein. We have demonstrated previously that a truncated TM glycoprotein with a 21-amino-acid-long cytoplasmic tail showed enhanced fusogenicity but could not be incorporated into virions. These results suggest that postassembly cleavage of the cytoplasmic domain removes a necessary incorporation signal and activates fusion activity. To investigate the contribution of tyrosine residues to the function of the glycoprotein complex and virus replication, we have introduced amino acid substitutions into two tyrosine residues found in the cytoplasmic domain. The effects of these mutations on glycoprotein biosynthesis and function, as well as on virus infectivity, have been examined. Mutation of tyrosine 34 to alanine had little effect on glycoprotein function. In contrast, substitutions at tyrosine 22 modulated fusion activity in either a positive or negative manner, depending on the substituting amino acid. Moreover, any nonaromatic substitution at this position blocked glycoprotein incorporation into virions and abolished infectivity. These results demonstrate that M-PMV employs a tyrosine signal for the selective incorporation of glycoprotein into budding virions. Antibody uptake studies show that tyrosine 22 is part of an efficient internalization signal in the cytoplasmic domain of the M-PMV glycoprotein that can also be positively and negatively influenced by changes at this site.

Formation of vacancy point-defects in hydroxyapatite nanobelts by selective incorporation of Fe3+ ions in Ca(II) sites. A CL and XPS study

2021 ◽  
Vol 271 ◽  
pp. 115308
Author(s):  
K. Carrera ◽  
V. Huerta ◽  
V. Orozco ◽  
J. Matutes ◽  
P. Fernández ◽  
...  
Keyword(s):  
Point Defects ◽  
Selective Incorporation ◽  
Xps Study

Carbon Monoxide Bond Cleavage Mediated by an Intramolecular Frustrated Lewis Pair: Access to New B/N Heterocycles via Selective Incorporation of Single Carbon Atoms

2021 ◽  
Author(s):  
Clemens Krempner ◽  
Chamila Manankandayalage ◽  
Daniel K Unruh
Keyword(s):  
Carbon Monoxide ◽  
Bond Cleavage ◽  
Frustrated Lewis Pair ◽  
Selective Incorporation

Utilizing an intramolecular frustrated Lewis pair (FLP) decorated with a strongly donating guanidino moiety enabled the formation of a thermally remarkably stable FLP-CO adduct, which at 120°C underwent CO migration...

Selective Incorporation of Hetes into Epidermal Phospholipids

1991 ◽  
pp. 409-419 ◽  
Author(s):  
Craig C. Miller ◽  
Wilson Tang ◽  
Yunhi Cho ◽  
Vincent A. Ziboh
Keyword(s):  
Selective Incorporation

scholarly journals Selective incorporation of dissolved organic matter (DOM) during sea ice formation

2013 ◽  
Vol 155 ◽  
pp. 148-157 ◽  
Author(s):  
Susann Müller ◽  
Anssi V. Vähätalo ◽  
Colin A. Stedmon ◽  
Mats A. Granskog ◽  
Louiza Norman ◽  
...  
Keyword(s):  
Organic Matter ◽  
Dissolved Organic Matter ◽  
Sea Ice ◽  
Ice Formation ◽  
Selective Incorporation

Current-confining structure of InGaN hexagonal microfacet lasers by selective incorporation of Mg during selective-area MOVPE

2003 ◽  
Vol 248 ◽  
pp. 537-541 ◽  
Author(s):  
Tetsuya Akasaka ◽  
Seigo Ando ◽  
Toshio Nishida ◽  
Tadashi Saitoh ◽  
Naoki Kobayashi
Keyword(s):  
Selective Area ◽  
Selective Incorporation

Proteome analysis using selective incorporation of isotopically labeled amino acids

2000 ◽  
Vol 11 (1) ◽  
pp. 78-82 ◽  
Author(s):  
Timothy D. Veenstra ◽  
Suzana Martinović ◽  
Gordon A. Anderson ◽  
Ljiljana Paša-Tolić ◽  
Richard D. Smith
Keyword(s):  
Amino Acids ◽  
Proteome Analysis ◽  
Selective Incorporation

scholarly journals Cover Picture: A Facile Strategy for Selective Incorporation of Phosphoserine into Histones (Angew. Chem. Int. Ed. 22/2013)

2013 ◽  
Vol 52 (22) ◽  
pp. 5651-5651
Author(s):  
Sangsik Lee ◽  
Seunghee Oh ◽  
Aerin Yang ◽  
Jihyo Kim ◽  
Dieter Söll ◽  
...  
Keyword(s):  
Selective Incorporation
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