When special populations intersect with drug‐drug interactions: application of physiologically‐based pharmacokinetic modeling in pregnant populations

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2272 ◽

2021 ◽

Author(s):

Caroline Sychterz ◽

Aleksandra Galetin ◽

Kunal S. Taskar

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Special Populations ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug‐Drug Interactions or in Special Populations: An Example Using Tofacitinib

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1679 ◽

2020 ◽

Vol 60 (12) ◽

pp. 1617-1628

Author(s):

Susanna Tse ◽

Martin E. Dowty ◽

Sujatha Menon ◽

Pankaj Gupta ◽

Sriram Krishnaswami

Keyword(s):

Drug Interactions ◽

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Special Populations ◽

Potential Drug ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug‐Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1378 ◽

2019 ◽

Vol 59 (6) ◽

pp. 880-889 ◽

Cited By ~ 1

Author(s):

Phuong Thi Thu Nguyen ◽

Md Masud Parvez ◽

Min Jung Kim ◽

Sung Eun Yoo ◽

Sangzin Ahn ◽

...

Keyword(s):

Genetic Polymorphism ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically based pharmacokinetic modeling to predict complex drug-drug interactions: a case study of AZD2327 and its metabolite, competitive and time-dependent CYP3A inhibitors

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.1962 ◽

2015 ◽

Vol 36 (8) ◽

pp. 507-519 ◽

Cited By ~ 4

Author(s):

Jian Guo ◽

Diansong Zhou ◽

Yan Li ◽

Bui H. Khanh

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Time Dependent ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Complex Drug

Download Full-text

Pain Chemogenomics Knowledgebase (Pain-CKB) for Systems Pharmacology Target Mapping and Physiologically Based Pharmacokinetic Modeling Investigation of Opioid Drug–Drug Interactions

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.0c00372 ◽

2020 ◽

Vol 11 (20) ◽

pp. 3245-3258

Author(s):

Mingzhe Shen ◽

Maozi Chen ◽

Tianjian Liang ◽

Siyi Wang ◽

Ying Xue ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Systems Pharmacology ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics

Frontiers in Pharmacology ◽

10.3389/fphar.2019.01672 ◽

2020 ◽

Vol 10 ◽

Cited By ~ 2

Author(s):

Jeffry Adiwidjaja ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Potential Drug ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Optimal Dosing ◽

Physiologically Based ◽

Dosing Regimens

Download Full-text

Physiologically‐Based Pharmacokinetic Modeling for Predicting Drug Interactions of a Combination of Olanzapine and Samidorphan

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12488 ◽

2020 ◽

Vol 9 (2) ◽

pp. 106-114 ◽

Cited By ~ 2

Author(s):

Lei Sun ◽

Lisa Moltke ◽

Karen Rowland Yeo

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically based pharmacokinetic modeling of disposition and drug–drug interactions for atorvastatin and its metabolites

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2015.06.019 ◽

2015 ◽

Vol 77 ◽

pp. 216-229 ◽

Cited By ~ 18

Author(s):

Tao Zhang

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Prediction of Renal Transporter Mediated Drug-Drug Interactions for Pemetrexed Using Physiologically Based Pharmacokinetic Modeling

Drug Metabolism and Disposition ◽

10.1124/dmd.114.059618 ◽

2014 ◽

Vol 43 (3) ◽

pp. 325-334 ◽

Cited By ~ 36

Author(s):

Maria M. Posada ◽

James A. Bacon ◽

Karen B. Schneck ◽

Rommel G. Tirona ◽

Richard B. Kim ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Renal Transporter

Download Full-text

A physiologically based pharmacokinetic modeling approach to predict drug-drug interactions between domperidone and inhibitors of CYP3A4

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.1992 ◽

2016 ◽

Vol 37 (1) ◽

pp. 15-27 ◽

Cited By ~ 8

Author(s):

Ian Templeton ◽

Paulien Ravenstijn ◽

Carlo Sensenhauser ◽

Jan Snoeys

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Predicting Drug–Drug Interactions Between Rifampicin and Long-Acting Cabotegravir and Rilpivirine Using Physiologically Based Pharmacokinetic Modeling

The Journal of Infectious Diseases ◽

10.1093/infdis/jiy726 ◽

2018 ◽

Vol 219 (11) ◽

pp. 1735-1742 ◽

Cited By ~ 9

Author(s):

Rajith K R Rajoli ◽

Paul Curley ◽

Justin Chiong ◽

David Back ◽

Charles Flexner ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Long Acting

Download Full-text