Quality and safety control of tumor-shrinking decoction (TSD): A Chinese herbal preparation for the treatment of uterine fibroids

2016 ◽  
Vol 64 (1) ◽  
pp. 126-133 ◽  
Author(s):  
Xiao-Xin Chen ◽  
Wai Ling Lin ◽  
Wing Fai Yeung ◽  
Tian-He Song ◽  
Li-Xing Lao ◽  
...  
Keyword(s):  
Uterine Fibroids ◽  
Quality And Safety ◽  
Herbal Preparation ◽  
Safety Control ◽  
Chinese Herbal

A randomized double blind, placebo controlled trial of a Chinese herbal preparation (CH100) in chronic Hepatitis C

2001 ◽  
Vol 120 (5) ◽  
pp. A384-A384
Author(s):  
L MOLLISON ◽  
L TOTTEN ◽  
C HOVELL ◽  
K THAYNE ◽  
C CONNELLY ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Controlled Trial ◽  
Herbal Preparation ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Chinese Herbal

System of quality and safety management in medical organization. Modern state

2019 ◽  
Vol 2019 (6) ◽  
pp. 15-23 ◽  
Author(s):  
Игорь Иванов ◽  
Igor' Ivanov
Keyword(s):  
Medical Care ◽  
Internal Control ◽  
Safety Management ◽  
Internal Quality ◽  
Modern State ◽  
Quality And Safety ◽  
Main Attention ◽  
Medical Organization ◽  
Safety Control

The article presents main approaches to provision of quality and safety of medical organization’s activities. The main attention is focused on the issues of implementation of the Suggestions (recommended practice) of Roszdravnadzor on organization of the internal quality and safety control of medical activities, as well as particular points of the Order of June 7, 2019 No. 381n “On Approval of Requirements for organization and conduction internal control of the quality and safety of medical care in hospitals”.

scholarly journals Hyperspectral Imaging Applications in Agriculture and Agro-Food Product Quality and Safety Control: A Review

2013 ◽  
Vol 48 (2) ◽  
pp. 142-159 ◽  
Author(s):  
Laura M. Dale ◽  
André Thewis ◽  
Christelle Boudry ◽  
Ioan Rotar ◽  
Pierre Dardenne ◽  
...  
Keyword(s):  
Product Quality ◽  
Hyperspectral Imaging ◽  
Food Product ◽  
Quality And Safety ◽  
Safety Control ◽  
Product Quality And Safety

scholarly journals Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway–Dependent Cerebral Microvascular Protection

2021 ◽  
Vol 12 ◽  
Author(s):  
Xiao-Di Fan ◽  
Ming-Jiang Yao ◽  
Bin Yang ◽  
Xiao Han ◽  
Ye-Hao Zhang ◽  
...  
Keyword(s):  
Brain Ischemia ◽  
Statistical Significance ◽  
Therapeutic Effects ◽  
Herbal Preparation ◽  
Model Group ◽  
Sod Activity ◽  
Nrf2 Pathway ◽  
Chinese Herbal ◽  
Therapeutic Mechanism

Stroke is one of the most devastating diseases worldwide. The Chinese herbal preparation SaiLuoTong (SLT) capsule showed outstanding therapeutic effects on stroke and its sequelae. The aim of this study was to further elucidate its therapeutic mechanism. We duplicated a permanent cerebral ischemia model in rats by MCAO and used SLT (33 and 16.5 mg/kg) to intervene. The results showed SLT dose dependently decreased infarction volumes, relieved neuron degeneration and loss, and ameliorated neurological functions, and the dose of 33 mg/kg had statistical significance (compared with the model group, p < 0.05); SLT of 33 mg/kg also significantly inhibited the elevation in brain water content and the loss in claudin-1 and occludin expressions; additionally, it significantly increased nucleus translocation of Nrf2, elevated the expression of HO-1, and raised the activity of SOD and content of GSH (compared with the model group, p < 0.05 or 0.01). These results testified SLT’s anti-brain ischemia effect and hint this effect may be related to the protection of brain microvascular endothelial cells (BMECs) that is dependent on the Nrf2 pathway. To further testify, we cultured hCMEC/D3 cells, duplicated OGD/R model to simulate ischemia, and used SLT (3.125, 6.25, and 12.5 mg/L) to treat. SLT dose dependently and significantly inhibited the drop in cell viabilities, and activated the Nrf2 pathway by facilitating Nrf2 nucleus translocation, and increasing HO-1 expression, SOD activity, and GSH content (compared with the model group, p < 0.05 or 0.01); last, the anti-OGD/R effects of SLT, including raising cell viabilities, inhibiting the elevation in dextran permeability, and preserving expressions of claudin-1 and occludin, were all abolished by Nrf2 siRNA interference. The in vitro experiment undoubtedly confirmed the direct protective effect of SLT on BMECs and the obligatory role of the Nrf2 pathway in it. Collectively, data of this study suggest that SLT’s therapeutic effect on brain ischemia is related to its Nrf2-dependent BMECs protection.

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