Synthesis of Peptidoglycan Fragments fromEnterococcus faecaliswith Fmoc-Strategy for Glycan Elongation

2016 ◽  
Vol 12 (1) ◽  
pp. 27-30 ◽  
Author(s):  
Ning Wang ◽  
Hiroki Hasegawa ◽  
Cheng-yuan Huang ◽  
Koichi Fukase ◽  
Yukari Fujimoto
Keyword(s):  
Fmoc Strategy

Synthesis of MUC1 Peptide and Glycopeptide Dendrimers

2009 ◽  
Vol 62 (10) ◽  
pp. 1339 ◽  
Author(s):  
Candy K. Y. Chun ◽  
Richard J. Payne
Keyword(s):  
Peptide Synthesis ◽  
Tandem Repeat ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis ◽  
Cycloaddition Reaction ◽  
Repeat Sequence ◽  
Tandem Repeat Sequence ◽  
Multiple Copies ◽  
Fmoc Strategy

Several dendrimers possessing multiple copies of peptides and glycopeptides belonging to the MUC1 eicosapeptide tandem repeat sequence have been prepared. Fmoc-strategy solid-phase peptide synthesis was used to construct the peptides and glycopeptides, which were conjugated to suitably functionalized dendrimer cores using the copper-catalyzed azide-alkyne cycloaddition reaction to produce multivalent peptide and glycopeptide dendrimers.

One-pot Deprotection and Coupling of Peptides by the Fmoc Strategy

1993 ◽  
Vol 22 (4) ◽  
pp. 721-724 ◽  
Author(s):  
Masaaki Ueki ◽  
Naohiko Nishigaki ◽  
Hiroko Aoki ◽  
Takeshi Tsurusaki ◽  
Tsuyoshi Katoh
Keyword(s):  
One Pot ◽  
Fmoc Strategy

Solid phase synthesis of insulin A-chain and analogues via Fmoc-strategy

Peptides 1994 ◽  
1995 ◽  
pp. 297-298
Author(s):  
S. G. Zakhariev ◽  
C. Guarnaccia ◽  
H.-G. Gattner ◽  
S. Pongor ◽  
D. Brandenburg
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
A Chain ◽  
Fmoc Strategy

Novel cysteine protecting groups for the Nα-9-fluorenylmethyloxycarbonyl (Fmoc) strategy of peptide synthesis

Peptides ◽  
1992 ◽  
pp. 605-606 ◽  
Author(s):  
Mark C. Munson ◽  
Carlos García-Echeverría ◽  
Fernando Albericio ◽  
George Barany
Keyword(s):  
Peptide Synthesis ◽  
Protecting Groups ◽  
Fmoc Strategy

Synthesis of Nanotubule-Forming Cyclic Octapeptides via an Fmoc Strategy

1998 ◽  
Vol 51 (7) ◽  
pp. 535 ◽  
Author(s):  
Martina E. Polaskova ◽  
John N. Lambert ◽  
Nicholas J. Ede
Keyword(s):  
Aqueous Solutions ◽  
Infrared Absorption ◽  
Structural Studies ◽  
Protection Strategy ◽  
Fmoc Chemistry ◽  
Orthogonal Protection ◽  
Fmoc Strategy ◽  
Cyclic Octapeptide ◽  
Head To Tail Cyclization ◽  
Hydrogen Bonded

New syndiotactic cyclic octapeptides, namely cyclo(–D-Phe-L-Asp–D-Phe–L-Asn–D-Phe–L-Asp–D-Phe–L-Asn–) (1) and cyclo(–D-N-MeAla–L-Asp–D-N-MeAla–L-Asn–D-N-MeAla–L-Asp–D-N-MeAla–L-Asn–) (2), have been prepared, and preliminary structural studies have been conducted. The synthesis of the linear peptides was performed by using Fmoc chemistry, and head-to-tail cyclization was accomplished by using an orthogonal protection strategy and a support-bound cyclization step. Acidification of aqueous solutions of cyclic octapeptide (1) initiated formation of needlelike crystals whose morphology and infrared absorption behaviour suggested that they were hydrogen-bonded nanotubular aggregates of (1).

Aqueous Microwave-Assisted Solid-Phase Peptide Synthesis Using Fmoc Strategy: In-Water Synthesis of "Difficult Sequences"

2012 ◽  
Vol 19 (11) ◽  
pp. 1231-1236 ◽  
Author(s):  
Keiko Hojo ◽  
Hideki Ichikawa ◽  
Asaki Hara ◽  
Mare Onishi ◽  
Koichi Kawasaki ◽  
...  
Keyword(s):  
Peptide Synthesis ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis ◽  
Microwave Assisted ◽  
Difficult Sequences ◽  
Fmoc Strategy

Synthesis of Peptides Influencing Growth Hormone Release

1994 ◽  
Vol 59 (3) ◽  
pp. 707-717 ◽  
Author(s):  
Jan Hlaváček ◽  
Otto Smékal ◽  
Jan Pospíšek ◽  
Tomislav Barth
Keyword(s):  
Growth Hormone ◽  
Cyclic Peptides ◽  
Solid Phase ◽  
Solid Phase Peptide Synthesis ◽  
Benzyl Ester ◽  
Linear Peptide ◽  
Alkaline Conditions ◽  
Merrifield Resin ◽  
Fmoc Strategy ◽  
By Products

A solid phase peptide synthesis of 17 growth hormone (GH) releasing peptide analogues Ia - IIIc for their use in a pharmacological assay on GH release is described. While the linear peptide amides Ia - Ij were synthesized on p-methylbenzhydrylamine resin using Boc strategy, and cleaved by HF in the presence of scavengers the linear peptide amides Ik and Il were prepared on Merrifield benzyl ester type resin using Fmoc strategy and cleaved by ammonolysis. The deleted peptide amides IIa and IIb were obtained as by-products during HPLC purification of analogues Ic and Id. The linear precursors of cyclic peptides IIIa - IIIc were also prepared on Merrifield resin and cleaved under mild alkaline conditions. Their cyclization was performed in solution by diphenylphosphoryl azide.

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