Highly Efficient Asymmetric Michael Addition of Diaryl Phosphine Oxides to α,β-Unsaturated N-Acylated Oxazolidin-2-ones

2012 ◽  
Vol 7 (5) ◽  
pp. 881-883 ◽  
Author(s):  
Depeng Zhao ◽  
Linqing Wang ◽  
Dongxu Yang ◽  
Yixin Zhang ◽  
Rui Wang
Keyword(s):  
Michael Addition ◽  
Phosphine Oxides ◽  
Highly Efficient ◽  
Asymmetric Michael Addition

ChemInform Abstract: Highly Efficient Amine Organocatalysts Based on Bispidine for the Asymmetric Michael Addition of Ketones to Nitroolefins.

ChemInform ◽  
2009 ◽  
Vol 40 (2) ◽  
Author(s):  
Zhigang Yang ◽  
Jie Liu ◽  
Xiaohua Liu ◽  
Zhen Wang ◽  
Xiaoming Feng ◽  
...  
Keyword(s):  
Michael Addition ◽  
Highly Efficient ◽  
Asymmetric Michael Addition

Highly Enantioselective Michael Addition of Dithiomalonates to Nitroolefins Catalyzed by New Bifunctional Chiral Thioureas

Synthesis ◽  
2018 ◽  
Vol 50 (13) ◽  
pp. 2577-2586 ◽  
Author(s):  
Jia-Ni Yuan ◽  
Hui-Xia Liu ◽  
Qin-Qin Tian ◽  
Nan Ji ◽  
Kuo Shen ◽  
...  
Keyword(s):  
Michael Addition ◽  
Mild Conditions ◽  
Highly Efficient ◽  
Michael Adducts ◽  
Asymmetric Michael Addition ◽  
High Yields

We report a highly efficient asymmetric Michael addition of dithiomalonates to trans-β-nitroolefins catalyzed by versatile cinchona-based bifunctional thioureas, which provides the corresponding adducts in high yields (up to 92%) and with excellent enantioselectivities (up to 99% ee) under mild conditions. Replacement of the catalyst with its pseudo-enantiomer gives the Michael adducts with opposite configuration in similar yields and enantioselectivities.

ChemInform Abstract: A Highly Efficient Asymmetric Michael Addition of α,α-Disubstituted Aldehydes to Maleimides Catalyzed by Primary Amine Thiourea Salt.

ChemInform ◽  
2011 ◽  
Vol 42 (7) ◽  
pp. no-no
Author(s):  
Feng Yu ◽  
Zhichao Jin ◽  
Huicai Huang ◽  
Tingting Ye ◽  
Xinmiao Liang ◽  
...  
Keyword(s):  
Michael Addition ◽  
Primary Amine ◽  
Highly Efficient ◽  
Asymmetric Michael Addition
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