Apremilast in Patients With Active Rheumatoid Arthritis: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study

Mark C. Genovese; Katerina Jarosova; Dorota Cieślak; Jeffrey Alper; Alan Kivitz; Douglas R. Hough; Peter Maes; Lilia Pineda; Mindy Chen; Farrukh Zaidi

doi:10.1002/art.39120

Apremilast in Patients With Active Rheumatoid Arthritis: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study

Arthritis & Rheumatology ◽

10.1002/art.39120 ◽

2015 ◽

Vol 67 (7) ◽

pp. 1703-1710 ◽

Cited By ~ 22

Author(s):

Mark C. Genovese ◽

Katerina Jarosova ◽

Dorota Cieślak ◽

Jeffrey Alper ◽

Alan Kivitz ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Phase Ii ◽

Active Rheumatoid Arthritis ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: Findings of a fifty-two-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study

Arthritis & Rheumatism ◽

10.1002/art.23964 ◽

2008 ◽

Vol 58 (11) ◽

pp. 3319-3329 ◽

Cited By ~ 387

Author(s):

Edward Keystone ◽

Désireé Van Der Heijde ◽

David Mason ◽

Robert Landewé ◽

Ronald Van Vollenhoven ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Active Rheumatoid Arthritis ◽

Certolizumab Pegol ◽

Phase Iii ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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Faculty Opinions recommendation of Efficacy and safety of sirukumab in patients with active rheumatoid arthritis refractory to anti-TNF therapy (SIRROUND-T): a randomised, double-blind, placebo-controlled, parallel-group, multinational, phase 3 study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727328077.793564275 ◽

2019 ◽

Author(s):

Ladislav Senolt

Keyword(s):

Rheumatoid Arthritis ◽

Active Rheumatoid Arthritis ◽

Efficacy And Safety ◽

Phase 3 ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group

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A multicentre, randomised, double blind, placebo controlled phase II study of subcutaneous interferon beta-1a in the treatment of patients with active rheumatoid arthritis

Annals of the Rheumatic Diseases ◽

10.1136/ard.2003.020347 ◽

2005 ◽

Vol 64 (1) ◽

pp. 64-69 ◽

Cited By ~ 56

Author(s):

J van Holten

Keyword(s):

Rheumatoid Arthritis ◽

Phase Ii ◽

Active Rheumatoid Arthritis ◽

Interferon Beta ◽

Phase Ii Study ◽

Double Blind ◽

Double Blind Placebo

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A Novel Highly Bioavailable Curcumin Formulation Improves Symptoms and Diagnostic Indicators in Rheumatoid Arthritis Patients: A Randomized, Double-Blind, Placebo-Controlled, Two-Dose, Three-Arm, and Parallel-Group Study

Journal of Medicinal Food ◽

10.1089/jmf.2017.3930 ◽

2017 ◽

Vol 20 (10) ◽

pp. 1022-1030 ◽

Cited By ~ 39

Author(s):

Augustine Amalraj ◽

Karthik Varma ◽

Joby Jacob ◽

Chandradhara Divya ◽

Ajaikumar B. Kunnumakkara ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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A randomised, double-blind, parallel-group study to demonstrate equivalence in efficacy and safety of CT-P13 compared with innovator infliximab when coadministered with methotrexate in patients with active rheumatoid arthritis: the PLANETRA study

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2012-203090 ◽

2013 ◽

Vol 72 (10) ◽

pp. 1613-1620 ◽

Cited By ~ 421

Author(s):

Dae Hyun Yoo ◽

Pawel Hrycaj ◽

Pedro Miranda ◽

Edgar Ramiterre ◽

Mariusz Piotrowski ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Active Rheumatoid Arthritis ◽

Efficacy And Safety ◽

Double Blind ◽

Parallel Group Study ◽

Parallel Group

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Efficacy and safety of iguratimod compared with placebo and salazosulfapyridine in active rheumatoid arthritis: a controlled, multicenter, double-blind, parallel-group study

Modern Rheumatology ◽

10.3109/s10165-006-0542-y ◽

2007 ◽

Vol 17 (1) ◽

pp. 1-9 ◽

Cited By ~ 42

Author(s):

Masako Hara ◽

Tohru Abe ◽

Sachiko Sugawara ◽

Yutaka Mizushima ◽

Keiko Hoshi ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Active Rheumatoid Arthritis ◽

Efficacy And Safety ◽

Double Blind ◽

Parallel Group Study ◽

Parallel Group

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Sa2051 A Phase II, Randomized, Double-Blind, Placebo-Controlled, Multiple-Dose, Parallel-Group Study to Evaluate the Efficacy, Safety, and Pharmacodynamics of RM-131 in Patients With Chronic Constipation

Gastroenterology ◽

10.1016/s0016-5085(14)61318-4 ◽

2014 ◽

Vol 146 (5) ◽

pp. S-364 ◽

Cited By ~ 6

Author(s):

Andres Acosta ◽

Gururaj Kolar ◽

Johanna Iturrino ◽

Lawrence A. Szarka ◽

Amy Boldingh ◽

...

Keyword(s):

Phase Ii ◽

Chronic Constipation ◽

Multiple Dose ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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THU0133 Results from A Phase 2A, Randomized, Multicenter, Double-Blind, Placebo-Controlled, Parallel-Group Study of Jnj-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-Modifying Antirheumatic Drug Therapy

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2014-eular.2404 ◽

2014 ◽

Vol 73 (Suppl 2) ◽

pp. 224.3-225

Author(s):

M.C. Genovese ◽

E. Hsia ◽

S. Belkowski ◽

C. Chien ◽

T. Masterson ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Drug Therapy ◽

Active Rheumatoid Arthritis ◽

Antirheumatic Drug ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group ◽

Disease Modifying ◽

Antirheumatic Drug Therapy ◽

Disease Modifying Antirheumatic Drug

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Effects of Tolvaptan on Volume Overload in Japanese Patients with Heart Failure: Results of a Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study

Cardiovascular Drugs and Therapy ◽

10.1007/s10557-011-6303-y ◽

2011 ◽

Vol 25 (S1) ◽

pp. 19-31 ◽

Cited By ~ 29

Author(s):

Masunori Matsuzaki ◽

◽

Masatsugu Hori ◽

Tohru Izumi ◽

Hidetsugu Asanoi ◽

...

Keyword(s):

Heart Failure ◽

Phase Ii ◽

Volume Overload ◽

Japanese Patients ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group ◽

Patients With Heart Failure

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Efficacy and safety of sirukumab in patients with active rheumatoid arthritis refractory to anti-TNF therapy (SIRROUND-T): a randomised, double-blind, placebo-controlled, parallel-group, multinational, phase 3 study

The Lancet ◽

10.1016/s0140-6736(17)30401-4 ◽

2017 ◽

Vol 389 (10075) ◽

pp. 1206-1217 ◽

Cited By ~ 53

Author(s):

Daniel Aletaha ◽

Clifton O Bingham ◽

Yoshiya Tanaka ◽

Prasheen Agarwal ◽

Regina Kurrasch ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Active Rheumatoid Arthritis ◽

Efficacy And Safety ◽

Phase 3 ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group

Download Full-text