A Reactive Oxygen Species-Mediated Loop Maintains Increased Expression of NADPH Oxidases 2 and 4 in Skin Fibroblasts From Patients With Systemic Sclerosis

2015 ◽  
Vol 67 (6) ◽  
pp. 1611-1622 ◽  
Author(s):  
Tatiana Spadoni ◽  
Silvia Svegliati Baroni ◽  
Donatella Amico ◽  
Lisa Albani ◽  
Gianluca Moroncini ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Systemic Sclerosis ◽  
Reactive Oxygen ◽  
Skin Fibroblasts ◽  
Oxygen Species ◽  
Nadph Oxidases

scholarly journals Correction: Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis

2014 ◽  
Vol 16 (2) ◽  
pp. 406
Author(s):  
Gianluca Bagnato ◽  
Alessandra Bitto ◽  
Natasha Irrera ◽  
Gabriele Pizzino ◽  
Donatella Sangari ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Systemic Sclerosis ◽  
Pulmonary Fibrosis ◽  
Murine Model ◽  
Reactive Oxygen ◽  
Oxygen Species

Redox signalling involving NADPH oxidase-derived reactive oxygen species

2006 ◽  
Vol 34 (5) ◽  
pp. 960-964 ◽  
Author(s):  
R. Dworakowski ◽  
N. Anilkumar ◽  
M. Zhang ◽  
A.M. Shah
Keyword(s):  
Reactive Oxygen Species ◽  
Nadph Oxidase ◽  
Second Messengers ◽  
Reactive Oxygen ◽  
Signalling Pathways ◽  
Cell Phenotype ◽  
Oxygen Species ◽  
Mechanical Stimuli ◽  
Nadph Oxidases ◽  
Redox Signalling

Increased oxidative stress plays an important role in the pathophysiology of many diseases such as atherosclerosis, diabetes mellitus, myocardial infarction and heart failure. In addition to the well-known damaging effects of oxygen-free radicals, ROS (reactive oxygen species) also have signalling roles, acting as second messengers that modulate the activity of diverse intracellular signalling pathways and transcription factors, thereby inducing changes in cell phenotype. NADPH oxidases appear to be especially important sources of ROS involved in redox signalling. Seven NADPH oxidase isoforms, known as Noxs (NAPDH oxidases), are expressed in a cell- and tissue-specific fashion. These oxidases are thought to subserve distinct functions as a result of their tightly regulated activation (e.g. by neurohormonal and growth factors and mechanical stimuli) and their specific coupling with distinct downstream signalling pathways. In the present paper, we review the structure and mechanisms of activation of NADPH oxidases and consider their involvement in redox signalling, focusing mainly on the cardiovascular system.

3,3′-Dihydroxyisorenieratene prevents UV-induced formation of reactive oxygen species and the release of protein-bound zinc ions in human skin fibroblasts

2009 ◽  
Vol 54 (2) ◽  
pp. 285-291 ◽  
Author(s):  
Kaya Lutter ◽  
Silke De Spirt ◽  
Sebastian Kock ◽  
Klaus-Dietrich Kröncke ◽  
Hans-Dieter Martin ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Human Skin ◽  
Reactive Oxygen ◽  
Skin Fibroblasts ◽  
Zinc Ions ◽  
Oxygen Species ◽  
Human Skin Fibroblasts

scholarly journals A Role for Reactive Oxygen Species Produced by NADPH Oxidases in the Embryo and Aleurone Cells in Barley Seed Germination

PLoS ONE ◽  
2015 ◽  
Vol 10 (11) ◽  
pp. e0143173 ◽  
Author(s):  
Yushi Ishibashi ◽  
Shinsuke Kasa ◽  
Masatsugu Sakamoto ◽  
Nozomi Aoki ◽  
Kyohei Kai ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Seed Germination ◽  
Reactive Oxygen ◽  
Barley Seed ◽  
Oxygen Species ◽  
Nadph Oxidases ◽  
Aleurone Cells

scholarly journals SUMO1 Negatively Regulates Reactive Oxygen Species Production From NADPH Oxidases

2011 ◽  
Vol 31 (7) ◽  
pp. 1634-1642 ◽  
Author(s):  
Deepesh Pandey ◽  
Feng Chen ◽  
Anand Patel ◽  
Cong-Yi Wang ◽  
Christiana Dimitropoulou ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen Species Production ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Nadph Oxidases ◽  
Species Production
Sign in / Sign up

Export Citation Format

Share Document