scholarly journals Validity in the Diagnosis of Reactive Hemophagocytic Syndrome: Comment on the Article by Fardet et al

2015 ◽  
Vol 67 (2) ◽  
pp. 587-588
Author(s):  
Shunichi Kumakura
Keyword(s):  
Hemophagocytic Syndrome ◽  
Reactive Hemophagocytic Syndrome

Reactive Hemophagocytic Syndrome Caused by Rickettsial Infection: Report of a Case

2012 ◽  
Vol 18 (2) ◽  
pp. 14-16 ◽  
Author(s):  
S. Anoun ◽  
Y. Traoue ◽  
A. Ouled Lahcen ◽  
K. Gamraoui ◽  
S. Faez ◽  
...  
Keyword(s):  
Hemophagocytic Syndrome ◽  
Rickettsial Infection ◽  
Reactive Hemophagocytic Syndrome

Development and Validation of the HScore, a Score for the Diagnosis of Reactive Hemophagocytic Syndrome

2014 ◽  
Vol 66 (9) ◽  
pp. 2613-2620 ◽  
Author(s):  
Laurence Fardet ◽  
Lionel Galicier ◽  
Olivier Lambotte ◽  
Christophe Marzac ◽  
Cedric Aumont ◽  
...  
Keyword(s):  
Hemophagocytic Syndrome ◽  
Reactive Hemophagocytic Syndrome ◽  
Development And Validation

Fulminant and rapidly fatal hemophagocytic lymphohistiocytosis in patients with HIV infection: A report of five cases and a review

2019 ◽  
Vol 30 (12) ◽  
pp. 1224-1228
Author(s):  
Paul Lam ◽  
Zeb Khan ◽  
Isha Bhatt ◽  
John Quale
Keyword(s):  
Hiv Infection ◽  
Hemophagocytic Lymphohistiocytosis ◽  
Hemophagocytic Syndrome ◽  
Ferritin Level ◽  
Survival Rates ◽  
Epstein Barr Virus Infection ◽  
Pneumocystis Jiroveci ◽  
Barr Virus ◽  
Reactive Hemophagocytic Syndrome ◽  
Cell Counts

Hemophagocytic lymphohistiocytosis is a rare entity and diagnosis can be elusive. Commonly recognized inciting causes include autoimmune disorders, malignancies, and a wide variety of infections. With prompt recognition and treatment, survival rates approach 50%. Five cases of reactive hemophagocytic syndrome in patients with underlying HIV infection are reported. All of the patients had CD3/CD4 cell counts of <200 cells/µL. All cases presented with fever and all had marked cytopenias, with platelet counts falling to 10–15,000/µL. Ferritin levels were >5000 ng/mL in all cases. Concomitant inciting conditions included Epstein–Barr virus infection, Pneumocystis jiroveci, multiple myeloma, and Hodgkin’s lymphoma; in one case, no inciting condition was identified. Despite broad-spectrum antimicrobial and immunosuppressive therapy, all five patients died within one month of presentation. The finding of fever and cytopenia in a patient with underlying HIV infection should prompt the clinician to determine a ferritin level. If markedly elevated, an aggressive work-up for hemophagocytic syndrome should be conducted. However, even with prompt recognition, mortality rates may be high in patients with underlying HIV infection.

Reactive Hemophagocytic Syndrome in Adults: A Retrospective Analysis of 162 Patients

2014 ◽  
Vol 127 (11) ◽  
pp. 1118-1125 ◽  
Author(s):  
Sébastien Rivière ◽  
Lionel Galicier ◽  
Paul Coppo ◽  
Christophe Marzac ◽  
Cedric Aumont ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Hemophagocytic Syndrome ◽  
Reactive Hemophagocytic Syndrome

Reactive Hemophagocytic Syndrome: A Report of Two Cases from Kuwait

1994 ◽  
Vol 14 (3) ◽  
pp. 257-259
Author(s):  
Soad Al-Bahar ◽  
Ramesh Pandita ◽  
Boman N. Dhabar ◽  
Ramesh Kumar
Keyword(s):  
Hemophagocytic Syndrome ◽  
Reactive Hemophagocytic Syndrome

Marked histiocytosis in the portal tract in a patient with reactive hemophagocytic syndrome: An autopsy case

1999 ◽  
Vol 49 (7) ◽  
pp. 672-675 ◽  
Author(s):  
Tadashi Terada ◽  
Hiroyuki Maeta ◽  
Kanenori Endo ◽  
Satoshi Horie ◽  
Yoshiko Matsunaga ◽  
...  
Keyword(s):  
Hemophagocytic Syndrome ◽  
Portal Tract ◽  
Autopsy Case ◽  
Reactive Hemophagocytic Syndrome

Reactive hemophagocytic syndrome as a presenting feature of Hodgkin's disease

2000 ◽  
Vol 79 (6) ◽  
pp. 322-326 ◽  
Author(s):  
L. Dawson ◽  
G. J. den Ottolander ◽  
P. M. Kluin ◽  
O. Leeksma
Keyword(s):  
Hodgkin's Disease ◽  
Hemophagocytic Syndrome ◽  
Hodgkin’S Disease ◽  
Reactive Hemophagocytic Syndrome

Reactive Hemophagocytic Syndrome

1985 ◽  
Vol 3 (2-4) ◽  
pp. 129-141 ◽  
Author(s):  
Sunita Arya ◽  
Richard Hong ◽  
Enid F. Gilbert
Keyword(s):  
Hemophagocytic Syndrome ◽  
Reactive Hemophagocytic Syndrome
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