scholarly journals A67: Factors That Contribute to Classification of Children as Having Undifferentiated Juvenile Idiopathic Arthritis

2014 ◽  
Vol 66 ◽  
pp. S98-S98 ◽  
Author(s):  
Mercedes O. Chan ◽  
Ross E. Petty ◽  
Kiem Oen ◽  
Ciarán M. Duffy ◽  
Lori B. Tucker ◽  
...  
2010 ◽  
Vol 63 (1) ◽  
pp. 267-275 ◽  
Author(s):  
Angelo Ravelli ◽  
Giulia C. Varnier ◽  
Sheila Oliveira ◽  
Esteban Castell ◽  
Olga Arguedas ◽  
...  

Genetics and JIA: HLA and non-HLA/MHC associations with subtypes of JIA 130Immunology and aetiology of JIA 137Classification of JIA 139JIA subtypes and their clinical presentations 141Prognostic indicators in JIA 146Uveitis screening in JIA: the approach to screening and guidelines 148...


2013 ◽  
Vol 40 (7) ◽  
pp. 1218-1225 ◽  
Author(s):  
Leslie R. Harrold ◽  
Craig Salman ◽  
Stanford Shoor ◽  
Jeffrey R. Curtis ◽  
Maryam M. Asgari ◽  
...  

Objective.Few studies based in well-defined North American populations have examined the occurrence of juvenile idiopathic arthritis (JIA), and none has been based in an ethnically diverse population. We used computerized healthcare information from the Kaiser Permanente Northern California membership to validate JIA diagnoses and estimate the incidence and prevalence of the disease in this well-characterized population.Methods.We identified children aged ≤ 15 years with ≥ 1 relevant International Classification of Diseases, 9th edition, diagnosis code of 696.0, 714, or 720 in computerized clinical encounter data during 1996–2009. In a random sample, we then reviewed the medical records to confirm the diagnosis and diagnosis date and to identify the best-performing case-finding algorithms. Finally, we used the case-finding algorithms to estimate the incidence rate and point prevalence of JIA.Results.A diagnosis of JIA was confirmed in 69% of individuals with at least 1 relevant code. Forty-five percent were newly diagnosed during the study period. The age- and sex-standardized incidence rate of JIA per 100,000 person-years was 11.9 (95% CI 10.9–12.9). It was 16.4 (95% CI 14.6–18.1) in girls and 7.7 (95% CI 6.5–8.9) in boys. The peak incidence rate occurred in children aged 11–15 years. The prevalence of JIA per 100,000 persons was 44.7 (95% CI 39.1–50.2) on December 31, 2009.Conclusion.The incidence rate of JIA observed in the Kaiser Permanente population, 1996–2009, was similar to that reported in Rochester, Minnesota, USA, but 2 to 3 times higher than Canadian estimates.


2009 ◽  
Vol 36 (8) ◽  
pp. 1725-1729 ◽  
Author(s):  
MADELEINE E. ROONEY ◽  
CATHERINE McALLISTER ◽  
JAMES F.T. BURNS

Objective.The ankle joint is frequently involved in juvenile idiopathic arthritis (JIA), but it is unclear whether this is predominantly due to synovitis, tenosynovitis, or both. We performed clinic-based ultrasound examination to assess the prevalence of synovitis and tenosynovitis in children with JIA felt clinically to have active inflammatory disease of the ankle.Methods.Thirty-four patients with 49 clinically swollen ankles were studied (19 polyarticular JIA, 13 oligoarticular JIA, 1 systemic JIA, 1 psoriatic JIA). All cases had at least one clinically swollen ankle joint. The children were assessed clinically and had ultrasound examination during routine clinic appointments.Results.We found 71% of ankles had tenosynovitis and 39% had tenosynovitis alone. Only 29% of swollen ankles had a tibiotalar effusion alone. We found 33% had both tenosynovitis and a tibiotalar effusion. When results were analyzed by JIA subtype, we found 81% of oligoarticular JIA ankles had medial ankle tenosynovitis but only 19% had tibiotalar effusion alone. There was a significant difference between JIA subgroups for the frequency of occurrence of medial ankle tenosynovitis (p = 0.048) and lateral ankle tenosynovitis (p = 0.001).Conclusion.The tibiotalar joint was not involved in 39% of the swollen ankles; and tenosynovitis, sometimes in isolation, was the dominant finding. This has implications for therapeutic intervention and also for an improved classification of children with JIA, especially with ankle involvement.


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