scholarly journals A58: Demographics, Clinical Features and Therapies of Patients with Juvenile Dermatomyositis Participating in a National Myositis Patient Registry

2014 ◽  
Vol 66 ◽  
pp. S86-S87 ◽  
Author(s):  
Lisa G Rider ◽  
Abdullah Faiq ◽  
Payam Noroozi Farhadi ◽  
Nastaran Bayat ◽  
Lukasz Itert ◽  
...  
Keyword(s):  
Clinical Features ◽  
Juvenile Dermatomyositis ◽  
Patient Registry ◽  
Myositis Patient

Clinical features, muscle biopsy scores, myositis specific antibody profiles and outcome in juvenile dermatomyositis

2021 ◽  
Vol 51 (1) ◽  
pp. 95-100
Author(s):  
Erdal Sag ◽  
Selcan Demir ◽  
Yelda Bilginer ◽  
Beril Talim ◽  
Goknur Haliloglu ◽  
...  
Keyword(s):  
Clinical Features ◽  
Muscle Biopsy ◽  
Specific Antibody ◽  
Juvenile Dermatomyositis

Inflammatory milieu of muscle biopsies and clinical features in juvenile dermatomyositis

2015 ◽  
Vol 25 ◽  
pp. S248
Author(s):  
E. Sag ◽  
S. Ozen ◽  
G. Kale ◽  
H. Topaloğlu ◽  
B. Talim
Keyword(s):  
Clinical Features ◽  
Juvenile Dermatomyositis ◽  
Inflammatory Milieu ◽  
Muscle Biopsies

scholarly journals Clinical features and disease course of patients with juvenile dermatomyositis

2013 ◽  
Vol 16 (5) ◽  
pp. 561-567 ◽  
Author(s):  
Peter J. Gowdie ◽  
Roger C. Allen ◽  
Andrew J. Kornberg ◽  
Jonathan D. Akikusa
Keyword(s):  
Clinical Features ◽  
Juvenile Dermatomyositis ◽  
Disease Course

scholarly journals Anti-Ro52 autoantibodies are associated with interstitial lung disease and more severe disease in patients with juvenile myositis

2019 ◽  
Vol 78 (7) ◽  
pp. 988-995 ◽  
Author(s):  
Sara Sabbagh ◽  
Iago Pinal-Fernandez ◽  
Takayuki Kishi ◽  
Ira N Targoff ◽  
Frederick W Miller ◽  
...  
Keyword(s):  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Lung Disease ◽  
Connective Tissue Disease ◽  
Clinical Features ◽  
Clinical Characteristics ◽  
Juvenile Dermatomyositis ◽  
Severe Disease ◽  
Trna Synthetase ◽  
Disease Course

ObjectivesAnti-Ro52 autoantibodies are associated with more severe interstitial lung disease (ILD) in adult myositis patients with antiaminoacyl transfer (t)RNA synthetase autoantibodies. However, few studies have examined anti-Ro52 autoantibodies in juvenile myositis. The purpose of this study was to define the prevalence and clinical features associated with anti-Ro52 autoantibodies in a large cohort of patients with juvenile myositis.MethodsWe screened sera from 302 patients with juvenile dermatomyositis (JDM), 25 patients with juvenile polymyositis (JPM) and 44 patients with juvenile connective tissue disease–myositis overlap (JCTM) for anti-Ro52 autoantibodies by ELISA. Clinical characteristics were compared between myositis patients with and without anti-Ro52 autoantibodies.ResultsAnti-Ro52 autoantibodies were found in 14% patients with JDM, 12% with JPM and 18% with JCTM. Anti-Ro52 autoantibodies were more frequent in patients with antiaminoacyl tRNA synthetase (64%, p<0.001) and anti-MDA5 (31%, p<0.05) autoantibodies. After controlling for the presence of myositis-specific autoantibodies, anti-Ro52 autoantibodies were associated with the presence of ILD (36% vs 4%, p<0.001). Disease course was more frequently chronic, remission was less common, and an increased number of medications was received in anti-Ro52 positive patients.ConclusionsAnti-Ro52 autoantibodies are present in 14% of patients with juvenile myositis and are strongly associated with anti-MDA5 and antiaminoacyl tRNA synthetase autoantibodies. In all patients with juvenile myositis, those with anti-Ro52 autoantibodies were more likely to have ILD. Furthermore, patients with anti-Ro52 autoantibodies have more severe disease and a poorer prognosis.

scholarly journals Association of Ultraviolet Radiation Exposure With Dermatomyositis in a National Myositis Patient Registry

2020 ◽  
Vol 72 (11) ◽  
pp. 1636-1644
Author(s):  
Christine G. Parks ◽  
Jesse Wilkerson ◽  
Kathryn M. Rose ◽  
Abdullah Faiq ◽  
Payam Noroozi Farhadi ◽  
...  
Keyword(s):  
Ultraviolet Radiation ◽  
Radiation Exposure ◽  
Patient Registry ◽  
Myositis Patient ◽  
Ultraviolet Radiation Exposure
Sign in / Sign up

Export Citation Format

Share Document