scholarly journals Association of Bone Morphogenetic Protein 6 With Exocrine Gland Dysfunction in Patients With Sjögren's Syndrome and in Mice

2013 ◽  
Vol 65 (12) ◽  
pp. 3228-3238 ◽  
Author(s):  
Hongen Yin ◽  
Javier Cabrera-Perez ◽  
Zhenan Lai ◽  
Drew Michael ◽  
Melodie Weller ◽  
...  
Keyword(s):  
Bone Morphogenetic Protein ◽  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Exocrine Gland ◽  
Morphogenetic Protein ◽  
Sjögren‘S Syndrome ◽  
Bone Morphogenetic Protein 6

Impact of Gender on Exocrine Gland Inflammation in Mouse Models of Sjögren's Syndrome

1999 ◽  
Vol 69 (4) ◽  
pp. 355-366 ◽  
Author(s):  
IKUKO TODA ◽  
BENJAMIN D SULLIVAN ◽  
EDUARDO M ROCHA ◽  
LILIA A DA SILVEIRA ◽  
L.ALEXANDRA WICKHAM ◽  
...  
Keyword(s):  
Sjögren’S Syndrome ◽  
Mouse Models ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Exocrine Gland ◽  
Sjögren‘S Syndrome

A severe form of sjogren's syndrome

1994 ◽  
Vol 108 (9) ◽  
pp. 806-807
Author(s):  
M. Puterman ◽  
D. M. Fliss ◽  
E. Ziskind ◽  
L. Laufer
Keyword(s):  
Autoimmune Disease ◽  
Parotid Gland ◽  
Sjögren’S Syndrome ◽  
Lacrimal Gland ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Severe Form ◽  
Exocrine Gland ◽  
Sjögren‘S Syndrome

AbstractSjogren's syndrome is an autoimmune disease characterized by exocrine gland destruction and manifested by parotid, submandibular and lacrimal gland infection. We report a case with recurrent severe parotid gland infections. The sialographic and CT findings are presented.

scholarly journals A link between interferon and augmented plasmin generation in exocrine gland damage in Sjögren's syndrome

2013 ◽  
Vol 40 ◽  
pp. 122-133 ◽  
Author(s):  
Maria Gliozzi ◽  
Teresa Greenwell-Wild ◽  
Wenwen Jin ◽  
Niki M. Moutsopoulos ◽  
Efstathia Kapsogeorgou ◽  
...  
Keyword(s):  
Sjögren’S Syndrome ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Exocrine Gland ◽  
Sjögren‘S Syndrome

The association of Raynaud’s phenomenon/syndrome with scleroderma and Sjögren’s syndrome – a meta-analysis

VASA ◽  
2008 ◽  
Vol 37 (Supplement 73) ◽  
pp. 26-32 ◽  
Author(s):  
Schlattmann ◽  
Höhne ◽  
Plümper ◽  
Heidrich
Keyword(s):  
Quantitative Analysis ◽  
Sjögren’S Syndrome ◽  
Mixture Model ◽  
Sjögren's Syndrome ◽  
Meta Analysis ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Raynaud’S Syndrome ◽  
Raynaud's Syndrome ◽  
Sjögren‘S Syndrome

Background: In order to analyze the prevalence of Raynaud’s syndrome in diseases such as scleroderma and Sjögren’s syndrom – a meta-analysis of published data was performed. Methods: The PubMed data base of the National Library of Medicine was used for studies dealing with Raynaud’s syndrome and scleroderma or Raynaud’s syndroem and Sjögren’s syndrom respectively. The studies found provided data sufficient to estimate the prevalence of Raynaud’s syndrome. The statistical analysis was based on methods for a fixed effects meta-analysis and finite mixture model for proportions. Results: For scleroderma a pooled prevalence of 80.9% and 95% CI (0.78, 0.83) was obtained. A mixture model analysis found four latent classes. We identified a class with a very low prevalence of 11%, weighted with 0.15. On the other hand there is a class with a very high prevalence of 96%. Analysing the association with Sjögren’s syndrome, the pooled analysis leads to a prevalence of Raynaud’s syndrome of 32%, 95% CI(26.7%, 37.7%). A mixture model finds a solution with two latent classes. Here, 38% of the studies show a prevalence of 18.8% whereas 62% observe a prevalence of 38.3%. Conclusion: There is strong variability of studies reporting the prevalence of Raynaud’s syndrome in patients suffering from scleroderma or Sjögren’s syndrome. The available data are insufficient to perform a proper quantitative analysis of the association of Raynaud’s phenomenon with scleroderma or Sjögren’s syndrome. Properly planned and reported epidemiological studies are needed in order to perform a thorough quantitative analysis of risk factors for Raynaud’s syndrome.

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