scholarly journals Diuretic use, increased serum urate levels, and risk of incident gout in a population-based study of adults with hypertension: The Atherosclerosis Risk in Communities cohort study

2011 ◽  
Vol 64 (1) ◽  
pp. 121-129 ◽  
Author(s):  
Mara A. McAdams DeMarco ◽  
Janet W. Maynard ◽  
Alan N. Baer ◽  
Allan C. Gelber ◽  
J. Hunter Young ◽  
...  
Keyword(s):  
Cohort Study ◽  
Serum Urate ◽  
Population Based ◽  
Population Based Study ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk

scholarly journals Prevalence, Awareness, Treatment, and Control of Hypertension in the PERSIAN Cohort Study: JNC7 Versus ACC/AHA Guidelines Short Title: The Impacts of Hypertension Definition in Iran

2021 ◽  
Author(s):  
Sadaf G. Sepanlou ◽  
Farid Najafi ◽  
Hossein Poustchi ◽  
Mahboubeh Parsaeian ◽  
Ali Ahmadi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Guideline Implementation ◽  
Population Based ◽  
Joint National Committee ◽  
National Committee ◽  
Newly Diagnosed ◽  
Cross Sectional ◽  
Population Based Study ◽  
And Control ◽  
Seventh Report

Abstract In this cross-sectional population-based study, we used the baseline data of the Prospective Epidemiologic Research Studies in IrAN (PERSIAN) cohort study collected in Iran from 2014 to 2020. The main outcomes were the prevalence of hypertension and proportion of awareness, treatment, and control based on the 2017 ACC/AHA guideline compared to the seventh report of the Joint National Committee (JNC7). Of the total of 163770 participants, aged 35 to 70 years, 55.2% were female. The sex-age standardized prevalence of hypertension was 22.3% (95% CI: 20.6-24.1) based on the JNC7 guideline and 36.5% (31.1-41.8) based on the ACC/AHA guideline. A total of 24312 participants [14.1% [10.1, 18.1)] were newly diagnosed based on the ACC/AHA guideline. Compared to adults diagnosed with hypertension based on the JNC7 guideline, the newly diagnosed participants were mainly young literate males who had low levels of risk factors and were free from conventional comorbidities of hypertension. About 30.7% (25.9, 35.4) of them (4.3% of the entire population) were eligible for pharmacologic intervention based on the ACC/AHA guideline. Implementation of the new guideline may impose additional burden on health systems. However, early detection and management of elevated blood pressure may reduce the ultimate burden of hypertension in Iran.

scholarly journals The risk factors of COVID-19 in a longitudinal population-based study

2021 ◽  
Author(s):  
Hozhabr Jamali Atergeleh ◽  
Mohammad Hassan Emamian ◽  
Shahrbanoo Goli ◽  
Marzieh Rohani-Rasaf ◽  
Hassan Hashemi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Electronic System ◽  
Population Based ◽  
Polymerase Chain Reaction Test ◽  
Diabetic Patients ◽  
Population Based Study ◽  
Relative Risks ◽  
Polymerase Chain ◽  
Chain Reaction Test

The present longitudinal study aims to investigate the risk factors for getting COVID-19 in a population aged 50 to 74 years. Data were collected from Shahroud Eye Cohort Study and the electronic system of COVID-19 in Shahroud, northeast Iran. Participants were followed for about 13 months and predisposing factors for COVID-19 infection were investigated using log binomial model and by calculation of relative risks. From the beginning of the COVID-19 outbreak in Shahroud (February 20, 2020) to March 26, 2021, out of 4394 participants in the Eye Cohort Study, 271 (6.1%) were diagnosed with COVID-19 with a positive Reverse Transcription Polymerase Chain Reaction test on two nasopharyngeal and oropharyngeal swabs. Risk factors for getting COVID-19 were included male gender (Relative Risk (RR) = 1.51; 95% Confidence Intervals (CI), 1.15-1.99), BMI over 25 (RR = 1.03; 95% CI, 1.01-1.05) and diabetes (RR = 1.31; 95% CI, 1.02-1.67). Also, smoking (RR = 0.51; 95% CI, 0.28-0.93) and education (RR = 0.95; 95% CI, 0.92-0.98) had reverse associations. In conclusion men and diabetic patients and those who have BMI over 25, should be more alert to follow the health protocols related to COVID-19 and priority should be given to them considering COVID-19 vaccination.

scholarly journals Serum Urate, Genetic Variation, and Prostate Cancer Risk: Atherosclerosis Risk in Communities (ARIC) Study

2019 ◽  
Vol 28 (7) ◽  
pp. 1259-1261
Author(s):  
Anqi Wang ◽  
John R. Barber ◽  
Adrienne Tin ◽  
Angelo M. De Marzo ◽  
Anna Kottgen ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Genetic Variation ◽  
Cancer Risk ◽  
Prostate Cancer Risk ◽  
Serum Urate ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk ◽  
Aric Study

scholarly journals Plasma phospholipid very-long-chain SFAs in midlife and 20-year cognitive change in the Atherosclerosis Risk in Communities (ARIC): a cohort study

2020 ◽  
Vol 111 (6) ◽  
pp. 1252-1258
Author(s):  
Danni Li ◽  
Jeffrey R Misialek ◽  
Ma Jing ◽  
Michael Y Tsai ◽  
John H Eckfeldt ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Cohort Study ◽  
Cognitive Decline ◽  
Plasma Phospholipid ◽  
Cognitive Change ◽  
Word Recall ◽  
Digit Symbol Substitution Test ◽  
Atherosclerosis Risk In Communities ◽  
Atherosclerosis Risk ◽  
Long Chain

Abstract Background Very-long-chain SFAs (VLSFAs) have recently gained considerable attention as having beneficial effects on health and aging. Objectives The objective of this study was to assess the associations of plasma phospholipid VLSFAs [arachidic acid (20:0), behenic acid (22:0), tricosanoic acid (23:0), and lignoceric acid (24:0)] with 20-y cognitive decline in the Atherosclerosis Risk in Communities (ARIC) participants. Furthermore, this study compared the associations of plasma phospholipid VLSFAs with 5 common groups of fatty acids [i.e., total SFAs, total MUFAs, total ω-3 (n–3) PUFAs, total marine-derived ω-3 PUFAs, total ω-6 PUFAs]. Methods This study used a cohort study design of 3229 ARIC participants enrolled at the Minnesota field center. Fatty acids were measured at visit 1 (1987–1989); and cognition was assessed at visits 2 (1990–1992), 4 (1996–1998), and 5 (2011–2013) using 3 tests: the Delayed Word Recall Test (DWRT), the Digit-Symbol Substitution Test (DSST), and the Word Fluency Test (WFT). Results Higher proportions of plasma phospholipid total VLSFAs and each individual VLSFA were associated with less decline in WFT, a test of verbal fluency. For example, 1 SD higher in total VLSFAs at baseline was associated with 0.057 SD (95% CI: 0.018, 0.096, P = 0.004) less cognitive decline over 20 y as measured by WFT score. None of the 5 common fatty acid groups were associated with change in WFT, but a higher proportion of plasma phospholipid total MUFAs was associated with greater decline in DWRT; higher total ω-6 PUFAs with less decline in DWRT; and higher total ω-3 and total marine-derived ω-3 PUFAs with less decline in DSST. Conclusions This study suggests that higher proportions of plasma phospholipid VLSFAs in midlife may be associated with less 20-y cognitive decline.

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