scholarly journals Anti-citrullinated peptide antibody assays and their role in the diagnosis of rheumatoid arthritis

2009 ◽  
Vol 61 (11) ◽  
pp. 1472-1483 ◽  
Author(s):  
Rohit Aggarwal ◽  
Katherine Liao ◽  
Raj Nair ◽  
Sarah Ringold ◽  
Karen H. Costenbander
Keyword(s):  
Rheumatoid Arthritis ◽  
Peptide Antibody ◽  
Antibody Assays ◽  
Citrullinated Peptide

scholarly journals Comparison of nine second- and third-generation anti-cyclic citrullinated peptide antibody assays for the diagnosis of rheumatoid arthritis

2013 ◽  
Vol 36 (2) ◽  
pp. 104-114
Author(s):  
Nobuhide HAYASHI ◽  
Shunichi KUMAGAI ◽  
Kenichiro ONUMA ◽  
Kenichi UTO ◽  
Daisuke SUGIYAMA ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Third Generation ◽  
Cyclic Citrullinated Peptide ◽  
Peptide Antibody ◽  
Antibody Assays ◽  
Citrullinated Peptide

scholarly journals TO ASSESS THE SENSITIVITY AND SPECIFICITY OF SERUM ANTICYCLIC CITRULLINATED PEPTIDE ANTIBODY IN PATIENTS WITH RHEUMATOID ARTHRITIS IN A COMMUNITY HOSPITAL IN LAHORE, PAKISTAN

1969 ◽  
Vol 4 (2) ◽  
pp. 503-507
Author(s):  
BUSHRA GOHAR SHAH ◽  
HAMID JAVAID QURESHI ◽  
IZAZ UR REHMAN
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Sensitivity And Specificity ◽  
Cell Biology ◽  
Venous Blood ◽  
Research Work ◽  
Specific Marker ◽  
Cross Sectional ◽  
Peptide Antibody ◽  
Citrullinated Peptide

OBJECTIVES: To compare the sensitivity and specificity of serum anti-Cyclic Citrullinated Peptideantibody (anti-CCP) with serum rheumatoid factor in diagnosing rheumatoid arthritis (RA) in acommunity hospital in Lahore, Pakistan.DESIGN: Cross-sectional analytical study.PLACE & DURATION OF STUDY: Subjects were recruited from Fatima Memorial Hospital,Rheumatology Outpatient Department from January, 2010 to December, 2010. The research work wasconducted at Department of Physiology and Cell Biology of University of Health Sciences, Lahore.SUBJECTS & METHODS: Eighty diagnosed patients of rheumatoid arthritis and thirty normalhealthy controls were included in the study. After selection of subjects, written informed consent wasobtained. The venous blood sample was taken and secured in vacutainers. Serum was extracted bycentrifugation and stored at -20°C till analysis. Titers of anti-CCP and rheumatoid factor weredetermined by ELISA. The data obtained was analyzed by using SPSS version 16.0.RESULTS: The sensitivity and specificity of serum anti-CCP was found to be 58.6% and 86.7%respectively as compared to 47.5% and 83.3% for serum rheumatoid factor (RF) in diagnosingrheumatoid arthritis. Sensitivity of anti-CCP antibody in RF negative sub-group was 32.1%.CONCLUSION: Serum anti-CCP antibody is more sensitive and specific marker for diagnosis ofrheumatoid arthritis as compared to the rheumatoid factor.KEY WORDS: Rheumatoid Arthritis, Anti- Cyclic Citrullinated Peptide Antibody (ACCP), Rheumatoid Factor

scholarly journals Analysis of clinical significance of anti-cyclic citrullinated peptide antibody (anti-CCP antibody) in rheumatoid arthritis (RA).

2007 ◽  
Vol 30 (5) ◽  
pp. 408-413
Author(s):  
Kumiko SHIMOYAMA ◽  
Noriyoshi OGAWA ◽  
Tomoyuki SAKAI ◽  
Toshioki SAWAKI ◽  
Takafumi KAWANAMI ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Significance ◽  
Cyclic Citrullinated Peptide ◽  
Peptide Antibody ◽  
Citrullinated Peptide
Sign in / Sign up

Export Citation Format

Share Document